110 research outputs found

    Ambulatory blood pressure monitoring and renal functions in children with a solitary kidney

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    The aim of this study is to investigate the blood pressure (BP) profile, microalbuminuria, renal functions, and relations with remaining normal kidney size in children with unilateral functioning solitary kidney (UFSK). Sixty-six children with UFSK were equally divided into three groups: unilateral renal agenesis (URA), unilateral atrophic kidney (UAK), and unilateral nephrectomy (UNP). Twenty-two age-, weight-, and height-matched healthy children were considered as a control group. The serum creatinine level and first-morning urine microalbumin and creatinine concentrations were determined by the standard methods. Also, the BP profile was determined by ambulatory blood pressure monitoring (ABPM). We found that the serum creatinine level was higher and creatinine clearance was lower in each patient groups compared to those of the control group (p < 0.05). Compared with the controls, each group of patients had mean office, 24-h, daytime, and night-time systolic and diastolic BP values similar to those of the controls (p > 0.05). An inverse correlation was found between the renal size standard deviation scores (SDS) of normal kidneys and 24-h systolic and diastolic BP load SDS in all of the patients (p < 0.05; r = −0.372, r = −0.295, respectively). The observed relationship between renal size SDS and 24-h mean arterial pressure (MAP), systolic and diastolic BP load SDS suggests that children with UFSK should be evaluated by using ABPM for the risk of hypertension

    The role of hyperosmolality and hemodynamic alterations in radiocontrast nephropathy

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    In the present study we determined the hemodynamic parameters that are formed in rats with reduced renal mass (70-75 %) when radiocontrast material, hypertonic and isotonic solutions are infused. The rats from all three groups had statistically the same indirect blood pressures prior to nephrectomy and. after the nephrectomy the indirect blood pressure levels increased to the same level in all three groups. For all three groups the pulse rates exhibited no change after the nephrectomy. The direct blood pressure values obtained from the transducer in the A. Femoralis were same for all three groups. During the infusion the direct systolic and diastolic blood pressures of the rats that received radiocontrast material and 4.5 % NaCl exhibited statistically significant drops and lasts for three to five minutes. After the infusion, the BUN and serum creatinine levels of group that received radiocontrast material were significantly higher than that of the other groups. Consequently we can emphasize that hyperosmolality and the associated hemodynamic changes are not directly responsible for contrast associated nephropathy.In the present study we determined the hemodynamic parameters that are formed in rats with reduced renal mass (70-75 %) when radiocontrast material, hypertonic and isotonic solutions are infused. The rats from all three groups had statistically the same indirect blood pressures prior to nephrectomy and. after the nephrectomy the indirect blood pressure levels increased to the same level in all three groups. For all three groups the pulse rates exhibited no change after the nephrectomy. The direct blood pressure values obtained from the transducer in the A. Femoralis were same for all three groups. During the infusion the direct systolic and diastolic blood pressures of the rats that received radiocontrast material and 4.5 % NaCl exhibited statistically significant drops and lasts for three to five minutes. After the infusion, the BUN and serum creatinine levels of group that received radiocontrast material were significantly higher than that of the other groups. Consequently we can emphasize that hyperosmolality and the associated hemodynamic changes are not directly responsible for contrast associated nephropathy

    Etiological evaluation of chronic renal failure in children

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    Çukurova Üniversitesi Çocuk Nefroloji Bilim Dalında, 1986-1996 yılları arasında kronik böbrek hastalığı (KBH) olan 286 çocuk (178 erkek, 108 kız) takip edildi. Ortalama KBH başlangıç yaşı 99.01 ±51.42 ay ve primer böbrek hastalıkları sırasıyla; glomerulopatiler %40.5, herediter renal hastalıklar %4.5, üropatiler %27, renal agenezildisplazil hipoplazi %3, diğer renal hastalıklar %7 idi. KBH'lı %18 hastanın primer renal bozukluğu bilinmiyordu.: From 1986 to 1996, 286 children (178 boy s, 108 girls) with chronic renal failure (CRF) were followed in Çukurova University School of Medicine Department of Pediatric Nephrology. Their mean age at onset of CRF was 99.01 ± 51.42 months and primary renal disorders were as follows; glomerulopathies 40.5%, uropathies 27%, hereditary renal disorders 4.5 %, renal agenesisldysplasialhypoplasia 3%, other renal disorders 7%. Additionally, in 18% of patients with chronic renal failure, primary renal disorder was unknown

    Unilateral multicystic dysplastic kidney: Cukurova experience

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    WOS: 000293248800464

    Nephrocalcinosis associated with Schimke immuno-osseous dysplasia

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    WOS: 000293248800255

    CRP, PROCALCITONIN and IL-18 LEVELS IN REFLUX NEPHROPATHY

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    WOS: 000307274100384
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