POEMS syndrome manifested as systemic capillary leak syndrome a case report

The authors report a case of an old woman who presented with a history of repetitive dyspnea and inferior limbs edema episodes, up to the point she showed extreme anasarca, hypotension, hypoalbuminemia, hemoconcentration and cachexia, developing unexplained respiratory insufficiency until death, in spite of all interventions. A diagnosis was obtained by autopsia: multicentric Castleman’s disease manifested as capillary leak syndrome and possible POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes), all conditions of rare incidence and of an intriguing association

Smoke inhalation injury during enclosed-space fires: an update

In view of the tragic fire at a nightclub in the city of Santa Maria, Brazil, which culminated in the sudden death of 232 young people, we decided to review the literature regarding smoke inhalation injury caused by enclosed-space fires, which can be divided into direct thermal damage, carbon monoxide poisoning, and cyanide poisoning. Such injuries often call for immediate orotracheal intubation, either due to acute airway obstruction or due to a reduced level of consciousness. The diagnosis and the severity of the thermal injury can be determined by fiberoptic bronchoscopy. The levels of gases and gas by-products in the bloodstream should be assessed as rapidly as possible, even while still at the scene of the incident. First responders can also treat carbon monoxide poisoning, with immediate administration of oxygen at 100%, as well as cyanide poisoning, with oxygen therapy and hydroxocobalamin injectio

POEMS syndrome manifested as systemic capillary leak syndrome a case report

The authors report a case of an old woman who presented with a history of repetitive dyspnea and inferior limbs edema episodes, up to the point she showed extreme anasarca, hypotension, hypoalbuminemia, hemoconcentration and cachexia, developing unexplained respiratory insufficiency until death, in spite of all interventions. A diagnosis was obtained by autopsia: multicentric Castleman’s disease manifested as capillary leak syndrome and possible POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes), all conditions of rare incidence and of an intriguing association