Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review

Evidence shows that metabolic syndrome (MS) is associated with a greater risk of developing Parkinson’s disease (PD) because of the increase in oxidative stress levels along with other factors such as neuroinflammation and mitochondrial dysfunction. However, because some studies have reported that MS is associated with a lower risk of PD, the relationship between MS and PD should be investigated. This study aimed to investigate the effect of MS on PD. Two authors searched five electronic databases, namely, MEDLINE, PubMed, Scopus, PsycINFO, Web of Science, and Science Direct, for relevant articles between September and October 2020. After screening the title and abstract of all articles, 34 articles were selected for full-text review. Finally, 11 articles meeting the eligibility criteria were included in the study. The quality of articles was critically evaluated using the Joanna Briggs Institute. Overall, we evaluated data from 23,586,349 individuals (including healthy individuals, with MS and PD) aged 30 years or more. In cohort studies, the follow-up period varied between 2 and 30 years. MS contributed considerably to the increase in the incidence of PD. In addition, obesity, a component of MS, alone can increase the probability of developing neurodegenerative diseases. However, despite few studies on MS and PD, changes in cognitive function and more rapid progression of PD disease has been documented in patients with MS using methods commonly used in research

Relationship between vitamin D deficiency and psychophysiological variables: a systematic review of the literature

Vitamin D is a fat-soluble vitamin that plays a role not only in calcium homeostasis, but also in several other functions, including cell growth and immune functions, and is considered a neurosteroid. Vitamin D deficiency is highly prevalent worldwide and has been suggested to be associated with an increased risk of emotional disorders. Therefore, the association between vitamin D levels and psychophysiological disorders, such as depression, anxiety, and mood, has been investigated. To list these variables, a bibliographical literature research was conducted in the MEDLINE/PubMed, Web of Science, Scopus, Science Direct and PsycINFO databases, between November and December 2020, with no year limits of publication. The studies involved humans aged between 18 and 59 years without associated diseases. This review presents evidence of the main variables involved in this association, main tools used to verify these variables, and methods used to verify circulating vitamin D levels in populations. Most studies have indicated that the main psychophysiological variables involved with vitamin D levels are depression and anxiety followed by mood, and an association has been observed between increased serum vitamin D levels and reduction in symptoms of depression, anxiety, and mood, and there is a heterogeneity of methods for assessing vitamin D. More studies are clearly needed to improve our understanding of their role in modulating the psychophysiological aspects of vitamin D levels

Perception of the level of physical activity of university professors during the isolation of COVID-19 / Percepção do nível de atividade física dos professores universitários durante o isolamento da COVID-19

COVID-19 is characterized by a severe acute respiratory syndrome (SARS), caused by the SARS-CoV-2 coronavirus, which started in China, in Wuhan, spreading throughout the world in an advanced way and has become a global health emergency, affecting 216 countries. The most recent number of confirmed cases of COVID- 19 is> 23.3 million worldwide, including> 806.4 confirmed deaths, as well as having forced> 4 billion people to be confined to their homes. In Brazil, more than 3.5 million people have been infected, with a total of more than 114,250 confirmed deaths today. On January 30, 2020, WHO notified COVID-19 as the sixth international public health emergency. The uncertainty of not knowing when the pandemic will end can affect people's physical health and can lead to other associated symptoms. The objective of the study was to investigate the consequences that social isolation can cause in aspects of physical activity in teachers of all undergraduate courses at the Centro Universitário Escritor Osman da Costa Lins - UNIFACOL, in Vitória de Santo Antão-PE. A cross-sectional study was carried out. Data collection took place through online questionnaires containing sociodemographic information and levels of physical activity. There were 115 participants, of which 57.4% were male and 42.6% female. Regarding the level of physical activity, there was a statistically significant difference between the sexes in moderate-intensity and walking. And during the pandemic, there were more active women and more sedentary men