Supporting research and development in ambulance services: research for better healthcare in prehospital settings

Background This paper discusses recent developments in research support for ambulance trusts in England and Wales and how this could be designed to lead to better implementation, collaboration in and initiation of high-quality research to support a truly evidence-based service. Method The National Ambulance Research Steering Group was set up in 2007 to establish the strategic direction for involvement of regional ambulance services in developing relevant and well-designed research for improving the quality of services to patients. Results Ambulance services have been working together and with academic partners to implement research and to participate, collaborate and lead the design of research that is relevant for patients and ambulance services. Conclusion New structures to support the strategic development of ambulance and prehospital research will help address gaps in the evidence for health interventions and service delivery in prehospital and ambulance care and ensure that ambulance services can increase their capacity and capability for high-quality research

PCA and K-Means decipher genome

In this paper, we aim to give a tutorial for undergraduate students studying statistical methods and/or bioinformatics. The students will learn how data visualization can help in genomic sequence analysis. Students start with a fragment of genetic text of a bacterial genome and analyze its structure. By means of principal component analysis they ``discover'' that the information in the genome is encoded by non-overlapping triplets. Next, they learn how to find gene positions. This exercise on PCA and K-Means clustering enables active study of the basic bioinformatics notions. Appendix 1 contains program listings that go along with this exercise. Appendix 2 includes 2D PCA plots of triplet usage in moving frame for a series of bacterial genomes from GC-poor to GC-rich ones. Animated 3D PCA plots are attached as separate gif files. Topology (cluster structure) and geometry (mutual positions of clusters) of these plots depends clearly on GC-content.Comment: 18 pages, with program listings for MatLab, PCA analysis of genomes and additional animated 3D PCA plot

Constraining Right-Handed Scale Through Kaon Mixing in SUSY Left-Right Model

We study flavor-changing neutral current and CP violations in the minimal supersymmetric left-right model. We calculate the beyond-standard-model contributions to the neutral kaon mixing $\Delta M_K$ and $\epsilon$, and find possible to have a numerical cancelation between the contributions from the right-handed gauge boson and supersymmetric box diagram. With the cancelation, the right-handed $W$-boson mass scale can be lowered to about 2 TeV, well within the search limit of LHC.Comment: 12 pages, new figures adde

Forms of capital and career benefits of the MBA in china and the UK

This paper sets out the results of a research project which compares benefits from the MBA in China and the UK. Drawing on and modifying Bourdieu’s forms of capital theory, it highlights areas of commonality and difference. In particular it demonstrates that some forms of capital (e.g. institutional, social) transcend national boundaries and are equally valued in both contexts. Significant differences emerge within categories of cultural capital with Chinese respondents placing a higher value on more technical and UK respondents placing a higher value on personal and interpersonal skill components. Implications for the transferability of Western based management education to China are evaluated and discussed

GRB 060218/SN 2006aj: A Gamma-Ray Burst and Prompt Supernova at z=0.0335

We report the imaging and spectroscopic localization of GRB 060218 to a low-metallicity dwarf starburst galaxy at z = 0.03345 +/- 0.00006. In addition to making it the second nearest gamma-ray burst known, optical spectroscopy reveals the earliest detection of weak, supernova-like Si II near 5720 Angstroms (0.1c), starting 1.95 days after the burst trigger. UBVRI photometry obtained between 1 and 26 days post-burst confirms the early rise of supernova light, and suggests a short time delay between the gamma-ray burst and the onset of SN 2006aj if the early appearance of a soft component in the X-ray spectrum is understood as a ``shock breakout''. Together, these results verify the long-hypothesized origin of soft gamma-ray bursts in the deaths of massive stars.Comment: 5 pages, 2 figure

Sea flavor content of octet baryons and intrinsic five-quark Fock states

Sea quark contents of the octet baryons are investigated by employing an extended chiral constituent quark approach, which embodies higher Fock five-quark components in the baryons wave-functions. The well-known flavor asymmetry of the nucleon sea $\bar{d}-\bar{u}$, is used as input to predict the probabilities of $\bar{u}$, $\bar{d}$ and $\bar{s}$ in the nucleon, $\Lambda$, $\Sigma$ and $\Xi$ baryons, due to the intrinsic five-quark components in the baryons wave functions.Comment: 22 page

Improving dialysis adherence for high risk patients using automated messaging: Proof of concept

AbstractComorbidities and socioeconomic barriers often limit patient adherence and self-management with hemodialysis. Missed sessions, often associated with communication barriers, can result in emergency dialysis and avoidable hospitalizations. This proof of concept study explored using a novel digital-messaging platform, EpxDialysis, to improve patient-to-dialysis center communication via widely available text messaging and telephone technology. A randomized controlled trial was conducted through Washington University-affiliated hemodialysis centers involving ESRD patients with poor attendance, defined as missing 2–6 sessions over the preceding 12 weeks. A cross-over study design evaluated appointment adherence between intervention and control groups. Comparing nonadherence rates eight weeks prior to enrollment, median appointment adherence after using the system increased by 75%, and median number of unintended hospitalization days fell by 31%. A conservative cost-benefit analysis of EpxDialysis demonstrates a 1:36 savings ratio from appointment adherence. EpxDialysis is a low-risk, cost-effective, intervention for increasing hemodialysis adherence in high-risk patients, especially at centers caring for vulnerable and low-income patients.</jats:p

An open systems approach to calculating time dependent spectra

A new method to calculate the spectrum using cascaded open systems and master equations is presented. The method uses two state analyzer atoms which are coupled to the system of interest, whose spectrum of radiation is read from the excitation of these analyzer atoms. The ordinary definitions of a spectrum uses two-time averages and Fourier-transforms. The present method uses only one-time averages. The method can be used to calculate time dependent as well as stationary spectra.Comment: 8 pages, revtex, 18 figures, to be published in J.Mod.Op

Critical Temperature Tc and Charging Energy Ec between B-B layers of Superconducting diboride materials MgB2 in 3D JJA model

The diboride materials MB2 (M = Mg, Be, Pb, etc.) are discussed on the basis of the 3D Josephson junction array (JJA) model due to Kawabata-Shenoy-Bishop, in terms of the B-B layers in the diborides analogous to the Cu-O ones in the cuprates. We propose a possibility of superconducting materials with the MgB2-type structure which exhibit higher critical temperature Tc over 39K of MgB2. We point out a role of interstitial ionic atoms (e.g., Mg in MgB2) as capacitors between the B-B layers, which reduce the charging coupling energy in JJA.Comment: 3 pages, 1 figure included; to be published in J. Phys. Soc. Jpn. 70, No.10 (2001