Skills, Standards, and Sapp Nelson\u27s Matrix: Evaluating Research Data Management Workshop Offerings

Objective: To evaluate library workshops on their coverage of data management topics. Methods: We used a modified version of Sapp Nelson’s Competency Matrix for Data Management Skills, a matrix of learning goals organized by data management competency and complexity level, against which we compared our educational materials: slide decks and worksheets. We examined each of the educational materials against the 333 learning objectives in our modified version of the Matrix to determine which of the learning objectives applied. Conclusions: We found it necessary to change certain elements of the Matrix’s structure to increase its clarity and functionality: reinterpreting the “behaviors,” shifting the organization from the three domains of Bloom’s taxonomy to increasing complexity solely within the cognitive domain, as well as creating a comprehensive identifier schema. We appreciated the Matrix for its specificity of learning objectives, its organizational structure, the comprehensive range of competencies included, and its ease of use. On the whole, the Matrix is a useful instrument for the assessment of data management programming

Requirements for a successful full inclusion program

This research paper titled Requirements For A Successful Inclusion· Program , is a study of full inclusion programs. The introduction covers the history and early laws involving special education. The purpose of the study was to determine the requirements for a successful full inclusion program. There were four questions asked in the study. 1.What are teachers attitudes about full inclusion? 2. What types of children are most effectively included in a full inclusion program? 3. What are the benefits and concerns of parents whose children are in regular and special education classrooms involving a full inclusion program? 4. What types of resources do teachers, parents, or students need for full inclusion to be successful? The need for the study, the limitations of the study, and definitions of the study are included. Chapter II involves a review of the literature, starting with advantages of full inclusion. This section includes the benefits for teachers, students, and parents. Chapter Ill states the reasons against full inclusion. It lists teachers negative attitudes, student concerns, and parent concerns. This chapter also gives resources for teachers, students and parents. Summary, conclusions and recommendations are found in Chapter IV. This touches on the basic questions asked at the beginning of the paper and is followed by answers: What are the teachers\u27 attitudes about full inclusion? What types of children are best included in a full inclusion program? What do parents think and feel about their children being in a full inclusion program? What types of resources do teachers, parents, or students need for full inclusion to be successful? There are four conclusions drawn by the researcher from the literature reviewed in the paper

Small Finds, Space, and Social Context: Exploring Agency in Historical Archaeology

The George Washington Foundation Department of Archaeology has combined a number of excavation and artifact-recovery techniques with a deliberate approach to artifact research and analysis in the laboratory to enhance interpretations of past behaviors. This article describes the elements of this approach and provides a case study involving the numerous 18th-century wig hair curler fragments found at the boyhood home of George Washington. The historical record together with the material culture assemblage allow us to demonstrate that the Washington family engaged in a home-based system of wig maintenance, allowing the economically struggling Washington boys to don wigs, an essential element of male gentry attire. This approach illustrates that conscientious recovery and analysis of small finds, such as wig curlers, can provide data used to reveal a great deal about the agency and consumer motivations of their owners

Monitoring stream stage, channel profile, and aqueous conductivity with time domain reflectometry (TDR).

Time domain reflectometry (TDR) operates by propagating a radar frequency electromagnetic pulse down a transmission line while monitoring the reflected signal. As the electromagnetic pulse propagates along the transmission line, it is subject to impedance by the dielectric properties of the media along the transmission line (e.g., air, water, sediment), reflection at dielectric discontinuities (e.g., air-water or water-sediment interface), and attenuation by electrically conductive materials (e.g., salts, clays). Taken together, these characteristics provide a basis for integrated stream monitoring; specifically, concurrent measurement of stream stage, channel profile and aqueous conductivity. Here, we make novel application of TDR within the context of stream monitoring. Efforts toward this goal followed three critical phases. First, a means of extracting the desired stream parameters from measured TDR traces was required. Analysis was complicated by the fact that interface location and aqueous conductivity vary concurrently and multiple interfaces may be present at any time. For this reason a physically based multisection model employing the S11 scatter function and Cole-Cole parameters for dielectric dispersion and loss was developed to analyze acquired TDR traces. Second, we explored the capability of this multisection modeling approach for interpreting TDR data acquired from complex environments, such as encountered in stream monitoring. A series of laboratory tank experiments were performed in which the depth of water, depth of sediment, and conductivity were varied systematically. Comparisons between modeled and independently measured data indicate that TDR measurements can be made with an accuracy of {+-}3.4x10{sup -3} m for sensing the location of an air/water or water/sediment interface and {+-}7.4% of actual for the aqueous conductivity. Third, monitoring stations were sited on the Rio Grande and Paria rivers to evaluate performance of the TDR system under normal field conditions. At the Rio Grande site (near Central Bridge in Albuquerque, New Mexico) continuous monitoring of stream stage and aqueous conductivity was performed for 6 months. Additionally, channel profile measurements were acquired at 7 locations across the river. At the Paria site (near Lee's Ferry, Arizona) stream stage and aqueous conductivity data were collected over a 4-month period. Comparisons drawn between our TDR measurements and USGS gage data indicate that the stream stage is accurate within {+-}0.88 cm, conductivity is accurate within {+-}11% of actual, and channel profile measurements agree within {+-}1.2 cm

Detection of Nonnucleoside Reverse‐Transcriptase Inhibitor–Resistant HIV‐1 after Discontinuation of Virologically Suppressive Antiretroviral Therapy

Using standard and ultrasensitive techniques, we detected nonnucleoside reverse-transcriptase inhibitor–associated resistance mutations in 11 (20%) of 54 subjects who discontinued virologically suppressive nonnucleoside reverse-transcriptase inhibitor–containing antiretroviral therapy. Resistance was detected in 45% and 14% of subjects with a baseline human immunodeficiency virus type 1 RNA level of 51–400 copies/mL and ≤50 copies/mL, respectively. Mutations remained detectable for at least 48 weeks in some subjects

Food Insecurity Prevalence Across Diverse Sites During COVID-19: A Year of Comprehensive Data

Key Findings NFACT includes 18 study sites in 15 states as well as a national poll, collectively representing a sample size of more than 26,000 people. Some sites have implemented multiple survey rounds, here we report results from 22 separate surveys conducted during the year since the COVID-19 pandemic began in March 2020. 18 out of 19 surveys in 14 sites with data for before and since the pandemic began found an increase in food insecurity since the start of the COVID-19 pandemic as compared to before the pandemic. In nearly all surveys (18/19) that measured food insecurity both before and during the pandemic, more Black, Indigenous, and People of Color (BIPOC) were classified as food insecure during the pandemic as compared to before it began. Prevalence of food insecurity for BIPOC respondents was higher than the overall population in the majority of surveys (19/20) sampling a general population. In almost all surveys (21/22), the prevalence of food insecurity for households with children was higher than the overall prevalence of food insecurity. Food insecurity prevalence was higher for households experiencing a negative job impact during the pandemic (i.e. job loss, furlough, reduction in hours) in nearly all surveys and study sites (21/22). Food insecurity prevalence in most sites was significantly higher before COVID-19 than estimates from that time period. Reporting a percent change between pre and during COVID-19 prevalence may provide additional information about the rate of change in food insecurity since the start of the pandemic, which absolute prevalence of food insecurity may not capture. Results highlight consistent trends in food insecurity outcomes since the start of the COVID-19 pandemic, across diverse study sites, methodological approaches, and time

A Phase 2a clinical trial of Molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

Molnupiravir (800 mg dose) accelerated SARS-CoV-2 RNA clearance in patients with COVID-19 compared to placebo

Infectious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Virus in Symptomatic Coronavirus Disease 2019 (COVID-19) Outpatients: Host, Disease, and Viral Correlates

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectious virus isolation in outpatients with coronavirus disease 2019 (COVID-19) has been associated with viral RNA levels and symptom duration, little is known about the host, disease, and viral determinants of infectious virus detection.COVID-19 adult outpatients were enrolled within 7 days of symptom onset. Clinical symptoms were recorded via patient diary. Nasopharyngeal swabs were collected to quantitate SARS-CoV-2 RNA by reverse transcriptase polymerase chain reaction and for infectious virus isolation in Vero E6-cells. SARS-CoV-2 antibodies were measured in serum using a validated ELISA assay.Among 204 participants with mild-to-moderate symptomatic COVID-19, the median nasopharyngeal viral RNA was 6.5 (interquartile range [IQR] 4.7–7.6 log10 copies/mL), and 26% had detectable SARS-CoV-2 antibodies (immunoglobulin (Ig)A, IgM, IgG, and/or total Ig) at baseline. Infectious virus was recovered in 7% of participants with SARS-CoV-2 antibodies compared to 58% of participants without antibodies (prevalence ratio [PR] = 0.12, 95% confidence interval [CI]: .04, .36; P = .00016). Infectious virus isolation was also associated with higher levels of viral RNA (mean RNA difference +2.6 log10, 95% CI: 2.2, 3.0; P < .0001) and fewer days since symptom onset (PR = 0.79, 95% CI: .71, .88 per day; P < .0001).The presence of SARS-CoV-2 antibodies is strongly associated with clearance of infectious virus. Seropositivity and viral RNA levels are likely more reliable markers of infectious virus clearance than subjective measure of COVID-19 symptom duration. Virus-targeted treatment and prevention strategies should be administered as early as possible and ideally before seroconversion.NCT04405570