Mucinous carcinoma of rectum in an 11 year old child

The rarity of rectal carcinoma in children has prompted us to report this patient who presented with bleeding per rectum and constipation. Histopathological examination of biopsy revealed the growth to be a mucinous carcinoma of rectum and which was inoperable on exploratory laparotomy

Neonatal tooth with bilateral cleft lip and palate: A case report with review of literature

Natal and neonatal teeth are present in the oral cavity at birth and during the first 30 days of life, respectively. Management of such teeth is a treatment challenge. The incidence of such natal and neonatal teeth is reported to be 1 in every 1125-30,000 births, respectively. Cleft lip and palate (CLP) is a common dentofacial congenital anomaly of the oral cavity and may be present unilaterally or bilaterally. The occurrence of association of such teeth with unilateral and bilateral CLP cases is reported to be 2% and 10%, respectively. The presence of natal/neonatal teeth in the cleft area complicates the child’s health only in few cases. There is a paucity of information in the literature regarding the simultaneous occurrence of neonatal teeth in bilateral CLP cases. The present paper reported the management of a neonatal tooth present in association with complete bilateral CLP in a 12-day-old male child with review of literature

A complicated case of Plasmodium falciparum malaria with symmetrical peripheral gangrene with a review of literature

Malaria causes nearly one million deaths each year and with its recent re-emergence, several fatal complications are seen such as cerebral malaria, hypotension or shock, renal failure, pulmonary oedema/adult respiratory distress syndrome, and hypoglycaemia. Symmetric peripheral gangrene (SPG) is a severe but extremely rare complication of malaria. It has a rapid and sudden onset leading to necrosis which cannot be reversed. A 26 year old male was admitted and treated for complicated malaria and developed SPG. He was given intravenous artesunate, doxycyline, clopidogrel and acetyl salicyclic acid for the gangrene; however, he went into multiple organ dysfunction syndrome and septic shock and thus could not be resuscitated. We report this case to highlight that physicians treating malaria should always look for these signs for timely correction and to improve the patient outcome

Diagnostic implications of salivary biomarkers in COVID-19: A systematic review and meta-analysis

Background: The gold standard for COVID-19 diagnosis is RT-qPCR. Nevertheless, collecting nasopharyngeal swabs can lead to patient discomfort and pose significant risks to healthcare workers. Salivary glands are hosting SARS-COV2 due to angiotensin-converting enzyme-2, and salivary high viral load detection plays a vital role in virus transmission. Salivary diagnostics offers self-collection and non-invasive options. Objective: This study's objective is to validate the diagnostic accuracy of various salivary biomarkers in patients diagnosed with COVID-19 in comparison with PCR diagnosis. Methodology: According to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) declaration, this systematic review was carried out (PROSPERO registration number: CRD42020215011). A comprehensive electronic search was conducted for studies published before October 15, 2020, using the following databases: PubMed, Google Scholar, Cochrane, EMBASE, LILACS, and MEDLINE. Results: The meta-analysis includes the studies' diagnostic accuracy (sensitivity, specificity, and 95 percent confidence interval). The sensitivities for the different selected studies ranged from 76% to 92%, while the specificities ranged from 16% to 100%. Conclusion: The use of IgA salivary biomarkers could provide a promising non-invasive diagnostic adjunct for COVID-19 diagnosis

VOICE CONTROL ROBOT USING ARDUINO PICK AND PLACE OBJECT

vvvvA rescue robot is a robot that has been designed for the purpose of aiding in most rescueworkforces.Inmostofcommoncircumstancesthatskillrescuerobotsaremining fortunes, urban ruins, and imprisoned situations and blasts. This robot will help us in thesesituationsbyhelpinghumans.Themajorobjectiveofthisprojectistocontrolthe robot by using voice commands and to use in disaster regions. It is aimed for theusers to control a pick and place device through voice commands. Here the user can control all the movements of robot through voice commands to remove the objects in disaster regions.Itusesamicrophonetoconvertthegivenvoicecommandstoelectricalsignals andthissignalisrecognizedusingvoicerecognizerbymeansofavoicesensor.Thissensor is known as the VR Module. It will produce an output which is used by a controller to produce a control output. This output will drive the motor, thus robotic action takes place. It consists of L293D IC which will as a driving mechanism of the pick and place robot. Also, it has servomotor that helps for movement of arms. The two micro servos areusedingrippingtheobjectsatadistance.TheVRmoduleisusedheretorecognize the voice and give the output to microcontroller. If the signal is same with that of the trainedsignalinkeypad,theservoswillworkaccordingtoit.A rescue robot is a robot that has been designed for the purpose of aiding in most rescueworkforces.Inmostofcommoncircumstancesthatskillrescuerobotsaremining fortunes, urban ruins, and imprisoned situations and blasts. This robot will help us in thesesituationsbyhelpinghumans.Themajorobjectiveofthisprojectistocontrolthe robot by using voice commands and to use in disaster regions. It is aimed for theusers to control a pick and place device through voice commands. Here the user can control all the movements of robot through voice commands to remove the objects in disaster regions.Itusesamicrophonetoconvertthegivenvoicecommandstoelectricalsignals andthissignalisrecognizedusingvoicerecognizerbymeansofavoicesensor.Thissensor is known as the VR Module. It will produce an output which is used by a controller to produce a control output. This output will drive the motor, thus robotic action takes place. It consists of L293D IC which will as a driving mechanism of the pick and place robot. Also, it has servomotor that helps for movement of arms. The two micro servos areusedingrippingtheobjectsatadistance.TheVRmoduleisusedheretorecognize the voice and give the output to microcontroller. If the signal is same with that of the trainedsignalinkeypad,theservoswillworkaccordingtoit.

Effect of radial, concentric scratches on a steady state heat transfer through a fin of aluminum alloy 6061

The steady state heat transfer performance of the engine cylinder fin is investigated using ANSYS’s Workbench for understanding the effect of micro-scratches. The investigation was carried to incorporate new kinds of manufacturing techniques that will help for improving the performance and save the cost. The performance was improved with number of radial or concentric scratches due to the increase in surface area exposed for convective heat transfer. The tip temperature was decreased from 791.86 °C to 728.26 °C for 480 radial scratches, while the heat flux was increased from 4.5697 × 106 to 5.0317 × 106 W/m2. In the case of concentric scratches, the tip temperature was reduced to 589.47 °C and the heat flux was enhanced to 9.8531 × 106 W/m2 for 150 concentric scratches. The concentric pattern reduced temperature drastically, while the maximum heat flux is uplifted due to the high exposure of the fresh convective surface area upon the scratching normal to the direction of heat flow. For maintaining the safety temperature and improved heat dissipation, the non-conventional manufacturing process can be adopted to reduce the cost of fin and, most importantly, the fin length

BMTVDS2: a novel hybrid bioinspired model for task-and-VM-dependency and deadline aware scheduling via dual service level agreements

Abstract This paper discusses the design of a novel hybrid bioinspired model for task-and-VM-dependency and deadline aware scheduling via dual service level agreements. The model uses a combination of grey wolf optimization with the league championship algorithm, to perform efficient scheduling operations. These optimization techniques model a fitness function that incorporates task make-span, task deadline, mutual dependencies with other tasks, the capacity of VMs, and energy needed for scheduling operations. This assists in improving its scheduling performance for multiple use cases. To perform these tasks, the model initially deploys a task-based service level agreement (SLA) method, which assists in enhancing task and requesting-user diversity. This is followed by the design of a VM-based SLA model, which reconfigures the VM's internal characteristics to incorporate multiple task types. The model also integrates deadline awareness along with task-level and VM-level dependency awareness, which assists in improving its scheduling performance under real-time task and cloud scenarios. The proposed model is able to improve cloud utilization by 8.5%, increase task diversity by 8.3%, reduce the delay needed for resource provisioning by 16.5%, and reduce energy consumption by 9.1%, making for a wide variety of real-time cloud deployments

Laser-assisted multidisciplinary approach for closure and prevention of relapse of midline diastema

Midline diastema, which occurs as spacing between the upper central incisors, is a common occurrence seen in the pediatric population. In the ugly duckling stage of development; no treatment is generally advocated as the diastema is a transient one. When diastemas occur due to other pathologies, they pose several problems in relation to esthetics and speech in a growing child. With the advent of time, patient's demand for esthetics has greatly increased. Along with this, a less time-consuming treatment option is a favorite. Proper diagnosis of the diastema, unfolding its etiology, helps in devising an adequate treatment plan. This eventually will lead to stability of the final result. The present case report presents a different and unique approach for the esthetic closure of midline diastema following frenectomy procedure. The approach proves to be a quick and simple option for closure of midline diastemas in cases with concomitant incisal edge irregularities

A rare case of schizencephaly in an adult with late presentation

Schizencephaly, i.e., split brain, is a rare, congenital cerebral malformation. Magnetic resonance imaging is the best neuroimaging modality for its diagnosis. In literature, only few cases have been reported causing symptoms in adults. Symptomatic patients present as hemiparesis, developmental deficits to seizures. This condition is usually found at birth and presents during early years. Appropriate diagnosis of the disease is necessary to avoid incorrect treatment. Here, we present a rare case of left, unilateral, open lip schizencephaly in an adult patient presenting with partial seizures but with an asymptomatic childhood