Isolated granulocytic sarcoma of the pancreas: A tricky diagnostic for primary pancreatic extramedullary acute myeloid leukemia

We report two clinical cases of primary granulocytic sarcoma of the pancreas that were diagnosed on the surgical specimen. Atypical clinical and morphological presentations may have lead to pretherapeutic biopsies of the pancreatic mass in order to indicate primary chemotherapy. Literature review of this rare clinical presentation may help physicians to anticipate diagnostic and therapeutic strategies

Flow Induced Pulsations (FLIP) in 6-inch rough bore gas flexible pipes Test

International audienceSince the beginning of the 21 st century FLow-Induced Pulsations (FLIP) has been more and more experienced. The phenomenon is characterized by an acoustic wave that is created inside of the flexible pipe and that may lead to significant fatigue failure of the adjacent equipment. Flexible pipe integrity is not called into question regarding this phenomenon. In this context, a FLIP joint test involving an Oil Company, a Flexible Pipe supplier and a French research center was conducted end of 2016 at French laboratory in Poitiers. The test was performed in a 6'' internal diameter and 18-meter-long flexible pipe. Both flow directions were tested to assess the influence of the rounded edges of the carcass. On the one hand, this paper presents the experimental test setup and the main results that came out of the test. On the other hand, this paper also presents the comparison between tests results and analytical model outcome. Moreover, combining experiments and theoretical point of view enabled reproducing the phenomenon. A better understanding of the phenomenon will allow flexible pipes suppliers to propose mitigations or cancellation of FLIP to companies

Experimental analysis of the whistling of an industrial riser

International audienceThe acoustic field induced by a flow in a corrugated pipe has been studied for a long time. There has been renewed interest in the development of offshore gas exploitation using long riser lengths for gas transport. On such installations, the phenomenon can lead to a failure of the equipment adjacent to the risers. In this context, a Flow-Induced Pulsations (FLIP) test was performed in a 6" internal diameter and 18-meter-long flexible pipe. This riser was equipped with upstream and downstream measuring couplers on which were fixed hot wire velocity sensors, pressure sensors and microphones. A series of tests was conducted for various internal pressures and flow rates. We present a time-frequency analysis of the signals resulting from these tests as well as a correlation study between the various sensors. We observed that the signals measured in the whistling condition showed significant temporal and frequency fluctuations. We were able to show that the frequency fluctuations were related to the geometry of the riser. In addition, these analyses made it possible to show that the whistling exists at transverse acoustic frequencies of the riser while propagating at the convective velocity of the flow

INSTRUMENTED FLIP TEST AND STATIC PRESSURE INFLUENCE ON THE ONSET VELOCITY AND FREQUENCY ON AN INDUSTRIAL SCALE

International audienceSince the early 2000, Flow Induced Pulsations (FLIP) has been more and more encountered on platforms. This phenomenon generates high acoustic pressure pulsations that may cause noises up to one hundred and ten dB and significant fatigue stress levels in small piping either at topside or subsea equipment. The source of the phenomenon is inside of the flexible pipe but FLIP has no effect on it. Nevertheless, in case of FLIP experience companies may have to reduce their flow rate. Therefore, FLIP must be understood in order for the companies to avoid this constraint. In this frame, a FLIP test was performed with protagonists who are involved in the understanding of this phenomenon. The test was done in 2016 at CESAME Poitiers (France) in an eighteen meter-long and six-inch flexible pipe on an air open loop. The prototype was fully instrumented and pressures up to forty bars were tested and mass flow rates up to 6 kg.s-1 to reproduce the FLIP phenomenon. The test setup and signals analysis are presented in this paper. Moreover, FLIP onset velocities and frequencies are compared with TechnipFMC models. As a conclusion of this paper pressure influence for the six-inch tested on the FLIP initiation will be presented

Le contingent majoritaire de cellules indépendantes a-t-il un impact sur le pronostic des adénocarcinomes oesogastriques ? (étude cas témoins)

LILLE2-BU Santé-Recherche (593502101) / SudocSudocFranceF

INSTRUMENTED FLIP TEST AND STATIC PRESSURE INFLUENCE ON THE ONSET VELOCITY AND FREQUENCY ON AN INDUSTRIAL SCALE

International audienceSince the early 2000, Flow Induced Pulsations (FLIP) has been more and more encountered on platforms. This phenomenon generates high acoustic pressure pulsations that may cause noises up to one hundred and ten dB and significant fatigue stress levels in small piping either at topside or subsea equipment. The source of the phenomenon is inside of the flexible pipe but FLIP has no effect on it. Nevertheless, in case of FLIP experience companies may have to reduce their flow rate. Therefore, FLIP must be understood in order for the companies to avoid this constraint. In this frame, a FLIP test was performed with protagonists who are involved in the understanding of this phenomenon. The test was done in 2016 at CESAME Poitiers (France) in an eighteen meter-long and six-inch flexible pipe on an air open loop. The prototype was fully instrumented and pressures up to forty bars were tested and mass flow rates up to 6 kg.s-1 to reproduce the FLIP phenomenon. The test setup and signals analysis are presented in this paper. Moreover, FLIP onset velocities and frequencies are compared with TechnipFMC models. As a conclusion of this paper pressure influence for the six-inch tested on the FLIP initiation will be presented

Experimental analysis of the whistling of an industrial riser

International audienceThe acoustic field induced by a flow in a corrugated pipe has been studied for a long time. There has been renewed interest in the development of offshore gas exploitation using long riser lengths for gas transport. On such installations, the phenomenon can lead to a failure of the equipment adjacent to the risers. In this context, a Flow-Induced Pulsations (FLIP) test was performed in a 6" internal diameter and 18-meter-long flexible pipe. This riser was equipped with upstream and downstream measuring couplers on which were fixed hot wire velocity sensors, pressure sensors and microphones. A series of tests was conducted for various internal pressures and flow rates. We present a time-frequency analysis of the signals resulting from these tests as well as a correlation study between the various sensors. We observed that the signals measured in the whistling condition showed significant temporal and frequency fluctuations. We were able to show that the frequency fluctuations were related to the geometry of the riser. In addition, these analyses made it possible to show that the whistling exists at transverse acoustic frequencies of the riser while propagating at the convective velocity of the flow