Radio continuum observations of local star-forming galaxies using the Caltech Continuum Backend on the Green Bank Telescope

We observed radio continuum emission in 27 local (D < 70 Mpc) star-forming galaxies with the Robert C. Byrd Green Bank Telescope between 26 GHz and 40 GHz using the Caltech Continuum Backend. We obtained detections for 22 of these galaxies at all four sub-bands and four more marginal detections by taking the average flux across the entire bandwidth. This is the first detection (full or marginal) at these frequencies for 22 of these galaxies. We fit spectral energy distributions (SEDs) for all of the four-sub-band detections. For 14 of the galaxies, SEDs were best fit by a combination of thermal free-free and nonthermal synchrotron components. Eight galaxies with four-sub-band detections had steep spectra that were only fit by a single nonthermal component. Using these fits, we calculated supernova rates, total number of equivalent O stars, and star formation rates within each ~23 arcsecond beam. For unresolved galaxies, these physical properties characterize the galaxies' recent star formation on a global scale. We confirm that the radio-far-infrared correlation holds for the unresolved galaxies' total 33 GHz flux regardless of their thermal fractions, though the scatter on this correlation is larger than that at 1.4 GHz. In addition, we found that for the unresolved galaxies, there is an inverse relationship between the ratio of 33 GHz flux to total far-infrared flux and the steepness of the galaxy's spectral index between 1.4 GHz and 33 GHz. This relationship could be an indicator of the timescale of the observed episode of star formation.Comment: 36 pages, 9 figures; accepted for publication in ApJ. First and second author affiliation updated to reflect departmental name chang

Global Properties of Neutral Hydrogen in Compact Groups

Compact groups of galaxies provide a unique environment to study the evolution of galaxies amid frequent gravitational encounters. These nearby groups have conditions similar to those in the earlier universe when galaxies were assembled and give us the opportunity to witness hierarchical formation in progress. To understand how the compact group environment affects galaxy evolution, we examine the gas and dust in these groups. We present new single-dish GBT neutral hydrogen (HI) observations of 30 compact groups and define a new way to quantify the group HI content as the HI-to-stellar mass ratio of the group as a whole. We compare the HI content with mid-IR indicators of star formation and optical [g-r] color to search for correlations between group gas content and star formation activity of individual group members. Quiescent galaxies tend to live in HI-poor groups, and galaxies with active star formation are more commonly found in HI-rich groups. Intriguingly, we also find "rogue" galaxies whose star formation does not correlate with group HI content. In particular, we identify three galaxies (NGC 2968 in RSCG 34, KUG 1131+202A in RSCG 42, and NGC 4613 in RSCG 64) whose mid-IR activity is discrepant with the HI. We speculate that this mismatch between mid-IR activity and HI content is a consequence of strong interactions in this environment that can strip HI from galaxies and abruptly affect star-formation. Ultimately, characterizing how and on what timescales the gas is processed in compact groups will help us understand the interstellar medium in complex, dense environments similar to the earlier Universe.Comment: Accepted to A

Unveiling Extragalactic Star Formation Using Radio Recombination Lines: An Expanded Very Large Array Pilot Study With Ngc 253

Radio recombination lines (RRLs) are powerful, extinction-free diagnostics of the ionized gas in young, star-forming regions. Unfortunately, these lines are difficult to detect in external galaxies. We present the results of Expanded Very Large Array (EVLA) observations of the RRL and radio continuum emission at 33 GHz from NGC 253, a nearby nuclear starburst galaxy. We detect the previously unobserved H58{alpha} and H59{alpha} RRLs and make simultaneous sensitive measurements of the continuum. We measure integrated line fluxes of 44.3 {+-} 0.7 W m{sup -2} and 39.9 {+-} 0.8 W m{sup -2} for the H58{alpha} and H59{alpha} lines, respectively. The thermal gas in NGC 253 is kinematically complex with multiple velocity components. We constrain the density of the thermal gas to (1.4-4) x 10{sup 4} cm{sup -3} and estimate an ionizing photon flux of 1 x 10{sup 53} s{sup -1}. We use the RRL kinematics and the derived ionizing photon flux to show that the nuclear region of NGC 253 is not gravitationally bound, which is consistent with the outflow of gas inferred from the X-ray and H{alpha} measurements. The line profiles, fluxes, and kinematics of the H58{alpha} and H59{alpha} lines agree with those of RRLs at different frequencies confirming themore » accuracy of the previous, more difficult, high-frequency observations. We find that the EVLA is an order of magnitude more efficient for extragalactic RRL observations than the Very Large Array. These observations demonstrate both the power of the EVLA and the future potential of extragalactic RRL studies with the EVLA.« les

Unveiling Extragalactic Star Formation Using Radio Recombination Lines: An EVLA Pilot Study with NGC 253

Radio recombination lines (RRLs) are powerful, extinction-free diagnostics of the ionized gas in young, star-forming regions. Unfortunately, these lines are difficult to detect in external galaxies. We present the results of EVLA observations of the RRL and radio continuum emission at 33 GHz from NGC 253, a nearby nuclear starburst galaxy. We detect the previously unobserved H58a and H59a RRLs and make simultaneous sensitive measurements of the continuum. We measure integrated line fluxes of $44.3 \pm 0.7$ W m$^{-2}$ and $39.9 \pm 0.8$ W m$^{-2}$ for the H58a and H59a lines, respectively. The thermal gas in NGC 253 is kinematically complex with multiple velocity components. We constrain the density of the thermal gas to $1.4 - 4 \times 10^4$ cm$^{-3}$ and estimate an ionizing photon flux of $1 \times 10^{53}$ s$^{-1}$. We use the RRL kinematics and the derived ionizing photon flux to show that the nuclear region of NGC 253 is not gravitationally bound, which is consistent with the outflow of gas inferred from the X-ray and Halpha measurements. The line profiles, fluxes, and kinematics of the H58a and H59a lines agree with those of RRLs at different frequencies confirming the accuracy of the previous, more difficult, high frequency observations. We find that the EVLA is an order of magnitude more efficient for extragalactic RRL observations than the VLA. These observations demonstrate both the power of the EVLA and the future potential of extragalactic RRL studies with the EVLA.Comment: Accepted for publication in the ApJL EVLA Special Issue. Version with high resolution figures at http://www.astro.virginia.edu/~aak8t/data/rrl/ms.p

Mixed Candida albicans strain populations in colonized and infected mucosal tissues

Multilocus sequence typing of six Candida albicans colonies from primary isolation plates revealed instances of colony-to-colony microvariation and carriage of two strain types in single oropharyngeal and vaginal samples. Higher rates of colony variation in commensal samples suggest selection of types from mixed populations either in the shift to pathogenicity or the response to antifungal treatment

Characterization of herpes simplex virus clinical isolate Y3369 as a glycoprotein G variant and its bearing on virus typing

<p>Abstract</p> <p>Background</p> <p>Herpes simplex viruses exist as two major serotypes, type 1 (HSV-1) and type 2 (HSV-2). Determination of type, either HSV-1 or HSV-2, is important in accurate diagnosis and clinical control of transmission. Several tests are available for typing HSV, including a monoclonal antibody specific for glycoprotein G and several PCR assays.</p> <p>Findings</p> <p>A clinical isolate was identified as herpes simplex virus, but tested negative for both HSV-1 and HSV-2 antigens using type-specific monoclonal antibody assays. The isolate was determined to be HSV-1 by PCR analysis. A mutation which likely caused the monoclonal antibody non-reactivity was found in glycoprotein G. Phylogenetic analysis revealed two groups of HSV, one with the mutation and one without. Three population studies examining mutations in HSV-1 glycoprotein G were analyzed by chi-squared test. To this point, the epitope which the monoclonal antibody recognizes was only found in HSV-1 isolates from human European populations (<it>p </it>< 0.0001).</p> <p>Conclusions</p> <p>These findings suggest that the PCR-based methods for HSV typing may be more useful than the standard monoclonal antibody test in areas of the world where the variant in glycoprotein G is more prevalent.</p

A survey of UK medical schools' arrangements for early patient contact

Background: Many U.K. medical schools have patient contact in the first two years of the undergraduate course. Aim: To compare the purposes and organization of early patient contact in UK medical schools and to relate these arrangements to the schools' curricular objectives. Methods: A telephone survey of lead educators in UK medicals schools. Categories of contact were plotted against phases of the course to discern patterns of organisation. Results: The quantity of contact varies considerably (four to 65 days). There is a pattern, with learning objectives around the social context of health and illness preceding skills based work and integrated clinical knowledge for practice coming later. Schools fall into three categories: close adherence to the preclinical/clinical split, with limited early contact acting as an introduction to social aspects of health; provision of substantial patient contact to maximize the integration of knowledge and skills; and transitional, with limited clinical goals. General practice provides between one third and one half of early patient contact. Conclusions: Arrangements meet the objectives set by each school and reflect differing educational philosophies. Change is toward more early contact. There appears to be no national guidance which supports a minimum quantity of patient contact or specific educational purpose in the early years of U.K. basic medical training

Gauge Theory and the Excision of Repulson Singularities

We study brane configurations that give rise to large-N gauge theories with eight supersymmetries and no hypermultiplets. These configurations include a variety of wrapped, fractional, and stretched branes or strings. The corresponding spacetime geometries which we study have a distinct kind of singularity known as a repulson. We find that this singularity is removed by a distinctive mechanism, leaving a smooth geometry with a core having an enhanced gauge symmetry. The spacetime geometry can be related to large-N Seiberg-Witten theory.Comment: 31 pages LaTeX, 2 figures (v3: references added

Nurse-Initiated Treatment Reduces Costs for Acute Asthma in a Pediatric Emergency Department

Standardized emergency department (ED) pathways can improve care delivery to children with acute asthma, though their impact on hospitalization and costs is unclear. An Acute Asthma Care Pathway (AACP) that facilitates nurse initiation of treatment was implemented at a tertiary care pediatric ED using standard quality improvement methodology. The impact of implementation was assessed using process control methodology and multivariable time series analyses between pre- and post-implementation periods. Provision of a steroid within 30 minutes and 60 minutes of arrival increased by 21 and 22 percentage points respectively, IV magnesium sulfate administration increased by 30 percentage points, the proportion hospitalized decreased from 44.8% to 32.2%, and mean direct costs per patient decreased from $2,663 to$2,303 (13.5%). In multivariable analysis, these improvements remained significant. Implementation of the AACP improved timeliness of treatment, hospitalization, and direct costs of children receiving ED treatment for acute asthma