112 research outputs found
Nouvelles données sur le Miocène moyen marin ("Sallomacien") de Gironde (Bassin d'Aquitaine-France) Approche des paléoenvironnements New data about the maine Middle Miocene ("Sallomacian") of Gironde (Aquitaine Basin); paleoecological outline
The Mid Miocene marine formations of Salles area (former "Sallomacian" stage) have been studied again from numerous outcrops
and cores. The deep structural framework influences notably of the characteristics and distribution of the deposits, which are
neritic. The stratigraphy is stated precisely thanks to the planktonic fauna and floradetailed examination (probably Serravallian zones NN6 - N12). Several paleobiofacies are reconstituted from the rich invertebrate faunas, which give also paleoclimatic data
Macrocyclic lactone resistance on new grass leys — the putative role of accidental ‘dose-and-move’ strategies due to use of persistent macrocyclic lactone products
Breed differences in the pharmacokinetics of ivermectin administered subcutaneously to Holstein and Belgian Blue calves
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The relative plasma availabilities of ivermectin in reindeer (Rangifer tarandus tarandus) following subcutaneous and two different oral formulation applications
Profile of the urinary excretion of prednisolone and its metabolites in finishing bulls and cows treated with a therapeutic schedule
Administration of ivermectin to peridomestic cattle: a promising approach to target the residual transmission of human malaria
Antiparasitic Macrolides: General Pharmacological Properties and Usage Instructions in the African Veterinary Context
Antiparasitic macrolides (or endectocides) represent the most recent class of antiparasitic drugs. This class is homogeneous because of its unique and specific, glutaminergic, mode of action, and its pharmacological properties. These drugs have a spectrum of action directed against many nematodes, as well as many insects and mites. Their structures and associated galenic formulations also enable them to have a high remanent potential. Unfortunately, endectocides are generally used in African countries without any recording procedure. Moreover, the introduction of generic formulations facilitated massive and repetitive uses that have led to therapeutic failures. These drugs should be given a good set-up to be effective in an African tropical environment, in particular by taking into account the characteristics of local breeds and environmental constraints. The first element to consider is the choice of the most potent route of administration. At the same time, the differences observed between animal species targets as well as physiological peculiarities must lead to a better adapted use
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