Sermons and Discourses Delivered by Rev. H. B. Altmeyer Principally on the Gospels, Feasts of the Church and the Lives of the Saints During the Last Ten Years

Altmeyer published his first collection, Sermons Delivered Before Mixed Congregations, in 1911. In the Preface to this volume, Henry A. Brann, Rector of St. Agnes\u27 Church in New York, notes that this one had been printed at the request of many of his fellow clergy. Brann goes on to describe the sermons as correct...clear, terse, and plain, effectively combining the study of the dogmatic with the ethical teaching of the church.https://mds.marshall.edu/altmeyer_henryb/1001/thumbnail.jp

The spin content of the proton in full QCD

We present preliminary results on the proton spin structure function in full QCD. The measurement has been done using 4 flavours of staggered fermions and an improved definition of the lattice topological charge density.Comment: 3 pages, 3 figures, contribution to Lattice-97. Latex file including espcrc2.sty. The colour of a line in the first figure has been changed to avoid problems on some printer

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles

Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress. The minimal requirement for the assembly of VLPs for the coronavirus responsible for severe acute respiratory syndrome in humans (SARS-CoV) is still controversial. Recent studies have shown that SARS-CoV VLP formation depends on either M and E proteins or M and N proteins. Here we show that both E and N proteins must be coexpressed with M protein for the efficient production and release of VLPs by transfected Vero E6 cells. This suggests that the mechanism of SARS-CoV assembly differs from that of other studied coronaviruses, which only require M and E proteins for VLP formation. When coexpressed, the native envelope trimeric S glycoprotein is incorporated onto VLPs. Interestingly, when a fluorescent protein tag is added to the C-terminal end of N or S protein, but not M protein, the chimeric viral proteins can be assembled within VLPs and allow visualization of VLP production and trafficking in living cells by state-of-the-art imaging technologies. Fluorescent VLPs will be used further to investigate the role of cellular machineries during SARS-CoV egress.The University of Hong Kong and the French Ministry of Health

The spin content of the proton in quenched QCD

We present preliminary results on the proton spin structure function at zero momentum, in the quenched approximation. Our calculation makes use of a nonperturbative means of determining the multiplicative renormalization of the topological charge density.Comment: REVTEX, 6 pages, 1 PS figure attached. Pisa preprint IFUP-TH-14/9

Recursiveness, Switching, and Fluctuations in a Replicating Catalytic Network

A protocell model consisting of mutually catalyzing molecules is studied in order to investigate how chemical compositions are transferred recursively through cell divisions under replication errors. Depending on the path rate, the numbers of molecules and species, three phases are found: fast switching state without recursive production, recursive production, and itinerancy between the above two states. The number distributions of the molecules in the recursive states are shown to be log-normal except for those species that form a core hypercycle, and are explained with the help of a heuristic argument.Comment: 4 pages (with 7 figures (6 color)), submitted to PR

SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement

1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2. Antibody-mediated enhancement of SARS-CoV infection with anti-SARS-CoV Spike immune-serum was observed in vitro. 3. Antibody-mediated infection of SARS-CoV triggers entry into human haematopoietic cells via an FcγR-dependent and ACE2-, pH-, cysteine-protease-independent pathways. 4. The antibody-mediated enhancement phenomenon is not a mandatory component of the humoral immune response elicited by SARS vaccines, as pure neutralising antibody only could be obtained. 5. Occurrence of immune-mediated enhancement of SARS-CoV infection raises safety concerns regarding the use of SARS-CoV vaccine in humans and enables new ways to investigate SARS pathogenesis (tropism and immune response deregulation)