A Case with Anti TNF- α Induced Bullous Pemhigoid

Bruneau de Miré Ph. Coléoptères Carabiques endémiques ou d'origine tropicale de la région du Sous (Maroc méridional). In: Bulletin de la Société entomologique de France, volume 57 (9), novembre 1952. pp. 130-133

Effect of electroconvulsive therapy on oxidative metabolism in major depressive disorder

WOS: 000414860000016Purpose: Electroconvulsive therapy (ECT) has been shown to be effective for major depressive disorder. This study aimed to evaluate the association between ECT and the effects of ECT on total antioxidant level, total oxidant level, oxidative stress index in major depression. Material and Methods: The study group consisted of 23 inpatients with major depressive disorder defined by DSM-IV criteria and 22 healty volunteers. Socio-demographic and clinical information were collected using structured questionnaire. Venous blood samples were taken from patients and controls. The biochemical parameters analyzed were serum total antioxidant level, total oxidant level. Results: Total antioxidant level was lower in the major depressive disorder group compared with those of the controls before ECT. Total antioxidant levels were significantly increased with electrocunvulsive therapy in patient group. There was no significant difference for total antioxidant levels after ECT. There was no significant difference between patient and control groups in terms of total oxidant level and oxidative stress index before and after ECT. Conclusion: The results suggest that ECT leads to an increase in antioxidant levels in patients with major depressive disorder

Prevalence and characteristics of visual aura in idiopathic generalized epilepsy

Some patients with idiopathic/genetic generalized epilepsy (IGE) experience visual aura, which can confuse the diagnosis. We sought to determine the frequency and characteristics of visual auras in IGE patients. Among the 176 IGE patients, 4 men and 7 women reported visual auras (mean age - 24 years). Syndromic diagnoses were juvenile myoclonic epilepsy in four, eyelid myoclonia with absences (EMA) in three, juvenile absence epilepsy in three, and other in one. Visual auras consisted of flashing lights, macropsia, illusional movements, and blindness. Eyelid myoclonia with absences was significantly more common in the group with visual aura (3 of 11 patients vs. 8 of 165 IGE patients; P=0.02). Furthermore, photosensitivity was found significantly more common in IGE patients with visual aura (90% vs 46% of the total IGE patients) (P=0.004). In conclusion, the visual auras do not exclude a diagnosis of IGE. The presence of visual aura in the EMA syndrome is also remarkable. (C) 2012 Elsevier Inc. All rights reserved

The effect of different anti-inflammatory treatment strategies on process of atherosclerosis in ankylosing spondylitis patients

Our aim in this study was to examine the effects of different anti-inflammatory treatment strategies on the process of atherosclerosis, which is an important cause of mortality in ankylosing spondylitis (AS) patients, by examining the possible effect of treatments on inflammation, lipid profile and oxidative stress parameters in patients with AS

Late-Onset Myoclonic Epilepsy in Down Syndrome: Investigation of EPM1 Gene Mutations in two Cases

AbstractLate-onset myoclonic epilepsy is being increasingly recognized as a late complication inelderly patients with Down syndrome (DS) in association with cognitive decline. This specificsyndrome bears some broad clinical and EEG similarities to the progressive myoclonicepilepsies, particularly Unverricht-Lundborg disease (ULD). Our aim was to investigate apossible shared patho-genetic mechanism for clinico-physiological similarities in thesedifferent genetic syndromes. Two patients diagnosed with DS and late-onset myoclonicepilepsy were included in the study. Dodecamer repeats and other possible CSTB genemutations were investigated after isolation of DNA from their blood samples. No dodecamerrepeats and point mutations could be found. Our study did not show any mutations of EPM1gene on chromosome 21 but these findings could not exclude a shared genetic mechanism inthese syndromes