598 research outputs found

    Performance evaluation of ductless personalized ventilation in comparison with desk fans using numerical simulations

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    The performance of ductless personalized ventilation (DPV) was compared to the performance of a typical desk fan since they are both stand-alone systems that allow the users to personalize their indoor environment. The two systems were evaluated using a validated computational fluid dynamics (CFD) model of an office room occupied by two users. To investigate the impact of DPV and the fan on the inhaled air quality, two types of contamination sources were modelled in the domain: an active source and a passive source. Additionally, the influence of the compared systems on thermal comfort was assessed using the coupling of CFD with the comfort model developed by the University of California, Berkeley (UCB model). Results indicated that DPV performed generally better than the desk fan. It provided better thermal comfort and showed a superior performance in removing the exhaled contaminants. However, the desk fan performed better in removing the contaminants emitted from a passive source near the floor level. This indicates that the performance of DPV and desk fans depends highly on the location of the contamination source. Moreover, the simulations showed that both systems increased the spread of exhaled contamination when used by the source occupant

    BlueBot: A Case Study In Conversational AI Using Scripted Chatbots

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    In the past decade, chatbots, with the use of artificial intelligence (AI), have become more advanced in terms of data size and natural language processing (NLP). A chatbot is a program which receives input from a user, and outputs the requested information. They have many flexible use cases, ranging from industrial support systems to healthcare education. With the use of NLP, chatbots are able to understand and even mimic human conversation. This case study will analyze a Java-based scripted chatbot intended to achieve a human-like conversation by nesting various predefined topics. Scripted chatbots are chatbots with a predefined set of input and output text set by the developer. Furthermore, the chatbot in this case study will be able to express emotions through an array of images, creating a more friendly, human-like conversation

    Neuronal and Glial Expression of GluN2C and GluN2D NMDA Receptor Subunit mRNA in Different Regions of the Mouse Forebrain

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    N-methyl-D-aspartate (NMDA) receptors are a subtype of glutamate receptors that are widely expressed in the brain, where they mediate critical functions. While the actions of the predominate GluN2 NMDAR subunits, GluN2A and GluN2B are relatively well understood, the function of GluN2C and GluN2D in the telencephalon is largely unknown. To better understand the possible role of GluN2C and GluN2D subunits, we used fluorescence in situ hybridization together with multiple cell markers to define the distribution and type of cells expressing GluN2C and GluN2D mRNA. Also, a GluN2C-KO mouse was used as a negative control. GluN2C mRNA expression was only found in non-neuronal cells in the telencephalon (except for globus pallidus). In addition, a significant fraction of astrocytes expressed GluN2C mRNA. In contrast to GluN2C, GluN2D subunit mRNA colocalized with neuronal and not astrocyte markers in the telencephalon. In the thalamus, GluN2C and GluN2D mRNA showed region-specific distributions as previously reported, and both subunits mRNA were expressed in neurons. Consistent with these findings, cellular colocalization of GluN2C and GluN2D mRNA was found in the thalamus but not in the telencephalon, except for the globus pallidus. Furthermore, the type of GluN2D-expressing neurons was examined by colocalization with GAD67 mRNA and found to be GAD67-positive interneurons. Among GluN2 NMDA receptor subunits, GluN2C expression was selective to astrocytes in the telencephalon. This specific pattern of distribution could indicate a distinct function. Since glutamate and intracellular Ca2+ signaling are linked to glucose uptake in astrocytes, a potential role of GluN2C-containing NMDA receptors in regulating astrocytic glucose uptake was investigated using autoradioactive analysis. Compared to wild-type mice, GluN2C-KO mice were found to have less glucose uptake after ketamine-induced neuronal activation. These data suggest that GluN2C play a role in stimulating glucose transport into astrocytes. Taken together, defining the cell-type distribution of GluN2C and GluN2D helps in understanding their functions in the brain and discovering therapeutic targets to treat neurological diseases and psychiatric disorders

    ASSESSING SELF-ESTEEM IN UAE STUDENTS WITH AND WITHOUT SPECIAL NEEDS: PILOT STUDY USING ADAPTED ROSENBERG SCALE

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    Self-esteem is known to be the way that a person values and perceives him/herself. It is affected by many factors and impacts on the person’s life. The main objective of this study was to investigate possible differences on self-esteem between typical students and those who have been diagnosed with special educational needs. In addition, the study explores teachers’ awareness on the importance of self-esteem on children’s life and their recommendations for improving their students’ self-esteem in UAE schools. The study used a mixed methods design and was conducted in two phases. During the first phase a sample of 40 students was divided into 2 groups, one with typical students (N=20) and another with students with an official diagnosis (N=20) and Rosenberg self-esteem rating scale (Rosenberg, 1965) was used to evaluate the self-esteem levels of the participants. In the second phase, semi-structured interviews with two teachers were conducted. An Independent T-test was performed to assess differences on scores between the two groups and findings from this study indicated that there was a statistically significant difference on self-esteem scores between students with and without special education needs, t = 7.03, p = 0.05. In addition, analyzing the data from teachers’ interviews the study provides important recommendations on improving the self-esteem of students with determination in UAE schools which may result to significant improvement in students’ behavior and academic performance

    The Impact of poor glycaemic control on the prevalence of erectile dysfunction in men with type 2 Diabetes Mellitus: A Systematic Review.

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    To determine the impact of poor glycaemic control on the prevalence of erectile dysfunction among men with type 2 Diabetics aged 27 to 85 years.The databases Embase classic+Embase, Global health, Ovid Medline and PsychINFO, were searched for relevant studies in June 2014 using the keywords: (Diabetes Mellitus OR diabetes mellitus type2 OR DM2 OR T2DM OR insulin resistance) AND (erectile dysfunction OR sexual dysfunction OR impotence) AND glycaemic control.All study settings were considered (primary care, secondary care and tertiary care setting).Type 2 Diabetic Patients with erectile dysfunction.Included studies must include one of the following outcomes: (1) HBA1c for assess the level of glycaemic control; (2) Erectile dysfunction (any stage: IIEF-5 = 21 or less).Five cross-sectional studies involving 3299 patients were included. The findings pointed to a positive association between erectile dysfunction and glycaemic control. Three studies showed a significant positive association, while one study showed only a weak correlation and one study showed borderline significance. Patients age, diabetes mellitus duration, peripheral neuropathy and body mass index had positive association with erectile dysfunction. However, smoking and hypertension were not associated with erectile dysfunction in most included studies. Physical activity had a protective effect against erectile dysfunction.We may conclude that the risk of erectile dysfunction is higher in type 2 diabetic men with poor glycaemic control than those with good control

    Psychosocial and mental health challenges of international students compared to British students in UK universities

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    A thesis submitted to the University of Bedfordshire in partial fulfilment of the requirements for the degree of Doctor of PhilosophyAccording to Harman (2004), international students were one of the main sources of finance in the UK, US, Australia, Canada and New Zealand. These students may face many difficulties once they arrive in countries like the UK, trying to adjust to their new surroundings. They confront, for example, more difficulties and challenges than the British students beginning a university course, especially if English is not their first language and the culture of their motherland is substantially different from British culture. Apart from language and cultural barriers, other reported difficulties include high academic demand, missing family and friends, lack of social support, lower self-confidence, deficiencies with study skills and a need to have more assertiveness (Poyrazli et al., 2002). Currently, not enough research has been published regarding acculturative stress and social support, including its relationship with psychological mental health amongst international students studying at UK universities. The main purposes of this study were threefold: (1) investigate the association between mental health and psychosocial variables amongst both international and British students (in UK universities); (2) explore the perceptions, thoughts, and feelings of international students in the context of acculturation, while they study abroad in the UK universities; and finally (3) to triangulate and integrate the findings of this study obtained from two distinct approaches of combined results. A concurrent triangulation mixed methods design was employed, consisting of three main studies. (a) I (Pilot study): a quantitative study employing simple yet effective cross-sectional approaches through its intention to using sample data; (b) II (Main study): a quantitative method specifically utilising cross-sectional design using authoritative data; and (c) III: a qualitative research conducting semi-structured interviews (using two qualitative questionnaires) to examine the metaphors participants used to describe their experiences in the host society. Study I: A snowball purposive sampling technique was used to select 358 students (international and British) studying in UK universities. Three different UK universities were selected. Eight pre-existing questionnaires were first tested for validity and reliability, then were utilised to examine the relationships between mental health and seven other independent variables. Study II: A snowball purposive sampling technique was used to select 796 students (international and British) studying in UK universities. Ten different UK universities were selected. The previous eight pre-existing questionnaires used in Study I were used in Study II, but the difference was that GHQ-12 was replaced by GHQ-28, and the IAI and SAI forms of the Three Assimilation Indexes were excluded. Study III: A snowball purposive sampling technique was used to select 30 students (international) studying in three UK universities. A semi-structured interview was conducted with these students. This study used thematic analysis to categorise metaphors and analyse the qualitative data. With a response rate of 82%, Study I showed that international students from the Middle East are less affected by cultural distress than other students from outside of Europe. In addition, many students find themselves leaning more towards religion to deal with the new cultural environment. Study II had an 80% response rate and found that there was an association between three out of five predictor variables (coping flexibility, social support and coping) with mental health, for both international and British students. In addition, the study found that there was an association between three out of seven predictor variables (coping strategy, religious problem solving, and acculturation) with mental health in international students. In Study III, the metaphors supported the quantitative results in terms of finding that a substantial number of the respondents had negative feelings about living in the UK and found the new setting depressing. The findings of the two quantitative studies (Study I and Study II) found that there is an association between international students and British students and coping flexibility with mental health. This finding has been confirmed by Study III which addressed metaphorical phrases used by international students. These findings indicate that interventions are strongly required in order to prevent and control potential psychological problems in both groups. The main recommendations are that regular training sessions should be provided for all international students, giving strategies for coping with the new culture. It is concluded that social support played a moderating role in the relationship between culture stress as well as mental health only in international students. These findings imply that strategies could be created to help students to cope with their mental issues and reduce the impact of distress they experience during their study. This might have a positive effect on their academic achievement consequently

    Predicting intention to adopt B2B electronic commerce in Jordan: The moderating role of trust and dependency

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    Business to Business Electronic Commerce (B2B EC) has great potentials to extend firms’ competency and efficiency. As such, Jordan has an objective to increase the diffusion of this technology. Despite extensive government efforts, the adoption of B2B EC is still limited. Consequently, there have been extensive efforts to better understand the phenomena. Yet, documented findings regarding the determinants of the adoption are not altogether consistent. To provide more insight, this study developed a research model utilizing the Technological, Organizational, and Environmental (TOE) framework to identify the determinants of the firms’ propensity to adopt B2B EC. Since B2B EC is an inter-organizational phenomenon supporting transactions of partnerships, this study emphasizes the context of partnership characteristics. Grounded on inter-organizational theories, this study hypothesized that partnership characteristics, namely trust and dependency, moderate the role of TOE motivating factors. Moreover, given that B2B EC is used on both sides of the buyer/seller relationship, this study examined the differences and similarities in the perception of the marketing and purchasing departments regarding the determinants of the B2B EC adoption. A total of 798 questionnaires were self administrated to marketing and purchasing managers in 462 firms that have large registered capital in Jordan. In total, 114 marketing and 125 purchasing managers participated in this study. Marketing and purchasing responses were analyzed separately using the Partial Least Squares approach. The result revealed that the marketing and purchasing departments do have different views regarding the determinants of the adoption, specifically in terms of the role of Relative Advantage and Competition Pressure. Moreover, the results showed that the moderating role of trust was less pronounced. Meanwhile, the moderating role of dependency was partially supported particularly in the purchasing perspective. These findings have demonstrated how dependence asymmetries between trading partners may change the adoption motivations. They further explain the importance of considering the views of the business partner for the adoption to be done successfully

    Revisiting co-trimoxazole for the treatment of tuberculosis

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