ICAR: endoscopic skull‐base surgery

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Estudo piloto da prevalência do transtorno de déficit de atenção e hiperatividade entre crianças escolares na cidade do Salvador, Bahia, Brasil A pilot study of prevalence of hyperactivity and attention deficit disorder in scholar children in Salvador, Bahia, Brazil

O presente estudo se propõe a estimar a prevalência do transtorno de déficit de atenção e hiperatividade (TDAH) em escolares através de inquérito com professores. Foi realizado um estudo piloto baseado no total de alunos do ensino fundamental, em escolas da rede pública e privada da cidade do Salvador, BA. O instrumento diagnóstico utilizado foi a Escala de TDAH versão para professores. Oito crianças (5,3%) apresentavam alta probabilidade de ter o subtipo predominantemente desatento, três escolares (2%) apresentavam alta probabilidade de apresentar o subtipo predominantemente hiperativo/impulsivo e uma criança (0,6%) apresentava alta probabilidade de apresentar o subtipo combinado. Crianças com TDAH podem ter sérios problemas de funcionamento social. O problema não se resume aos déficits trazidos pela doença, mas à associação co-mórbida com outros transtornos, que pode resultar em comprometimento social grave. O reconhecimento precoce e o manejo adequado do TDAH pode redirecionar o desenvolvimento educacional e psicossocial dessas crianças.<br>This study aims to estimate the prevalence of attention deficit hyperactivity disorder (ADHD) in scholar children through a teacher's questionnaire. A pilot study was conducted based in the total number of students under high school, in public and private schools in Salvador, Bahia, Brazil. The instrument used was Teacher's version of ADHS scale. Eight kids (5.3%) were recognized as highly probability of attention deficit disorder, three (2%) with high probability of subtype hyperactive/impulsive, and one (0.6%) as combined subtype. Children with ADHD might have serious social problems, not only brought by the disorder, but also due to co morbidity with other disorders, leading to serious social withdrawn. Early diagnostic and treatment of ADHD might improve educational and psychosocial development of these kids

Comparison of the clinical efficacy of twice-daily Ritalin and once-daily Equasym XL with placebo in children with Attention Deficit/Hyperactivity Disorder

Objective To compare the efficacy and safety of two methylphenidate (MPH) formulations—once-daily modified-release MPH (EqXL, Equasym™ XL) and twice-daily immediate-release methylphenidate (MPH-IR, Ritalin®)—and placebo in children with Attention Deficit/Hyperactivity Disorder (ADHD). Methods Children aged 6–12 years on a stable dose of MPH were randomized into a double-blind, three-arm, parallel-group, multi-center study and received 3 weeks of EqXL (20, 40, or 60 mg qd), MPH-IR (10, 20, or 30 mg bid) or placebo. Non-inferiority of EqXL to MPH-IR was assessed by the difference in the inattention/overactivity component of the overall teacher’s IOWA Conners’ Rating Scale on the last week of treatment (per protocol population). Safety was monitored by adverse events, laboratory parameters, vital signs, physical exam, and a Side Effect Rating Scale. Results The lower 97.5% confidence interval bound of the difference between MPH groups fell above the non-inferiority margin (−1.5 points) not only during the last week of treatment but during all three treatment weeks. Both MPH-treatment groups experienced superior benefit when compared to placebo during all treatment weeks (P < 0.001). All treatments were well tolerated. Conclusions EqXL given once-daily was non-inferior to MPH-IR given twice-daily. Both treatments were superior to placebo in reducing ADHD symptoms

Ideology and Threat Perceptions: American Public Opinion toward China and Iran

What determines threat perceptions in the context of potential interstate conflict? We argue that such perceptions are to an important extent driven by domestic political cleavages and ideological differences. The ideology effects are often surprising and are more complex than the conventional wisdom would indicate. We specify the conditions under which conservatives may favor the economic rise of rising powers. Concern about budget deficits affects not only domestic political preferences but also threat perceptions. Finally, civil libertarianism in certain contexts can lead to isolationist preferences. We test these claims using the 2012 American National Election Studies data about the perceptions of American citizens of the economic and military rise of China, and of potential American responses to Iran’s nuclear program