89 research outputs found

    Mary Clifford Webster Darling Correspondence

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    Entries include some correct biographical information typed by the Maine State Library and handwritten correspondence on a Fredericka Manor card and plain paper stationery

    Ethan Allen Chase Correspondence

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    Entries include letters of correspondence from the Maine State Library to Allen\u27s granddaughter and a handwritten letter of presentation from Achilles

    Warren County - Place Names

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    A historical survey of community and place names in Warren County, Kentucky

    Kenneth Lewis Roberts Correspondence

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    Entries include brief biographical information, a typed biography, typed and handwritten correspondence on personal stationery from Kennebunk Beach, Maine, including a humorous letter in 1933 concerning the Society for Helping Maine Literature, his belief that the author collection was in need of Arnoldiana such as a donated pike head handmade by Arnold\u27s blacksmiths for the attack on Quebec, the manuscript of Arundel sent to be opened after publication and loaned to Leonard for Doubleday Doran and Company and a surprising Western Union telegram requesting permanent loan of the manuscript for MIT, handwritten and typed correspondence from Roberts in Italy including a handwritten artistic postcard from his wife, numerous biographical newspaper review clippings with photographic images, book synopses, and a poem for Theodore Roosevelt who could remember neither the author nor title of the book he was reading, a research question concerning Maine people on cookery, notes through the years concerning his friends, the staff at Doubleday, historians, libraries, and librarians as well as transition at the Maine Development Commission, correspondence with Mary A. Benjamin on Walter R. Benjamin, Autographs, stationery and a postcard concerning the possible sale of a copy of a Maine land grant document, a gift instead from Roberts of his vellum copy of the Trelawny-Goodyear grant of 1631, and the reply of Stubbs from the Maine State Library on receipt of this copy of the Casco Bay land grant

    Some Venezuelan birds

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    p. 51-56 ; 24 cm.Includes bibliographical references

    Automated Analysis of Risk Factors for Postictal Generalized EEG Suppression

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    Rationale: Currently, there is some ambiguity over the role of postictal generalized electro-encephalographic suppression (PGES) as a biomarker in sudden unexpected death in epilepsy (SUDEP). Visual analysis of PGES, known to be subjective, may account for this. In this study, we set out to perform an analysis of PGES presence and duration using a validated signal processing tool, specifically to examine the association between PGES and seizure features previously reported to be associated with visually analyzed PGES. Methods: This is a prospective, multicenter epilepsy monitoring study of autonomic and breathing biomarkers of SUDEP in adult patients with intractable epilepsy. We studied videoelectroencephalogram (vEEG) recordings of generalized convulsive seizures (GCS) in a cohort of patients in whom respiratory and vEEG recording were carried out during the evaluation in the epilepsy monitoring unit. A validated automated EEG suppression detection tool was used to determine presence and duration of PGES. Results: We studied 148 GCS in 87 patients. PGES occurred in 106/148 (71.6%) seizures in 70/87 (80.5%) of patients. PGES mean duration was 38.7 ± 23.7 (37; 1–169) seconds. Presence of tonic phase during GCS, including decerebration, decortication and hemi-decerebration, were 8.29 (CI 2.6–26.39, p = 0.0003), 7.17 (CI 1.29–39.76, p = 0.02), and 4.77 (CI 1.25–18.20, p = 0.02) times more likely to have PGES, respectively. In addition, presence of decerebration (p = 0.004) and decortication (p = 0.02), older age (p = 0.009), and hypoxemia duration (p = 0.03) were associated with longer PGES durations. Conclusions: In this study, we confirmed observations made with visual analysis, that presence of tonic phase during GCS, longer hypoxemia, and older age are reliably associated with PGES. We found that of the different types of tonic phase posturing, decerebration has the strongest association with PGES, followed by decortication, followed by hemi-decerebration. This suggests that these factors are likely indicative of seizure severity and may or may not be associated with SUDEP. An automated signal processing tool enables objective metrics, and may resolve apparent ambiguities in the role of PGES in SUDEP and seizure severity studies
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