580 research outputs found

    Friction of air in small pipes and fittings

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    The work of Park and Peterson during 1909-10 at the Missouri School of Mines revealed the fact that more data are needed concerning the loss of pressure due to elbows and other fittings of pipes under three inches in size. Accordingly, we decided to undertake the continuation of their work as a thesis. The apparatus used was practically the same as used in the previous thesis --page 1

    1935: Abilene Christian College Bible Lectures - Full Text

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    Delivered in the auditorium of Abilene Christian College, Abilene, Texas, February 193

    Preface

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    1. The issue The present special issue is developed from a workshop entitled Bantu Universals and Variation at the 10th World Congress of African Linguistics (WOCAL10) held online at Leiden University in June 2021. It includes a selection of papers presented at the workshop, as well as papers submitted in response to an open call for papers. The resultant special issue brings together new perspectives on universals and variation in the Bantu language family, with regards to morphosyntax, sema..

    Bantu word order between discourse and syntactic relations

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    Discourse function has often been noticed to be a strong factor in conditioning Bantu word order. The importance of discourse function for determining the word order of Bantu languages is visible for example in locative inversion and dedicated focus positions. As a result of such phenomena, it has been proposed that Bantu word order is best captured by reference to discourse roles, e.g. Topic-Verb-Nontopic. Nevertheless, we typically see statements describing Bantu word order in relation to grammatical roles (e.g. “SVO”), and the notions “subject” and “object” remain core in analyses of Bantu. In this paper we present the result of a study reconsidering Bantu word order from a discourse-configurational perspective, asking how far we can get without reference to grammatical roles. We use a parametric approach to investigate this syntactic variation, presenting new discourse-oriented field data collected on 9 Bantu languages. We show how these parameters highlight variation within the family, with each language sitting at a different point on a continuum between grammatical role-oriented and discourse role-oriented. We therefore argue against a one-size-fits-all account of Bantu word order and advocate for approaches that include both grammatical and discourse roles.La fonction discursive a souvent été identifiée comme un facteur important dans le conditionnement de l’ordre des mots en bantou. L’importance de la fonction discursive dans la détermination de l’ordre des mots des langues bantoues est visible par exemple dans l’inversion locative et les positions du focus. À la suite de tels phénomènes, il a été proposé que l’ordre des mots en bantou est mieux représenté par les rôles discursifs, par ex. Topique-Verbe-Non-topique. Néanmoins, nous observons généralement des déclarations décrivant l’ordre des mots bantou par rapport aux rôles grammaticaux (par exemple « SVO »), et les notions de « sujet » et « objet » restent au cœur des analyses du bantou. Dans cet article, nous présentons les résultats d’une étude reconsidérant l’ordre des mots bantou dans une perspective des configurations discursives, en nous demandant jusqu’où nous pouvons aller sans référence aux rôles grammaticaux. Nous utilisons une approche paramétrique pour étudier cette variation syntaxique, en présentant de nouvelles données de terrain, axées sur le discours, recueillies sur 9 langues bantoues. Nous montrons comment ces paramètres mettent en évidence la variation au sein de la famille, chaque langue se situant à un point différent sur un continuum entre les rôles grammaticaux et les rôles discursifs. Nous nous opposons donc à une description unique de l’ordre des mots bantou et préconisons des approches qui incluent à la fois les rôles grammaticaux et discursifs

    Aberrant development corrected in adult-onset Huntington's disease iPSC-derived neuronal cultures via WNT signaling modulation

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    Aberrant neuronal development and the persistence of mitotic cellular populations have been implicated in a multitude of neurological disorders, including Huntington's disease (HD). However, the mechanism underlying this potential pathology remains unclear. We used a modified protocol to differentiate induced pluripotent stem cells (iPSCs) from HD patients and unaffected controls into neuronal cultures enriched for medium spiny neurons, the cell type most affected in HD. We performed single-cell and bulk transcriptomic and epigenomic analyses and demonstrated that a persistent cyclin D1+ neural stem cell (NSC) population is observed selectively in adult-onset HD iPSCs during differentiation. Treatment with a WNT inhibitor abrogates this NSC population while preserving neurons. Taken together, our findings identify a mechanism that may promote aberrant neurodevelopment and adult neurogenesis in adult-onset HD striatal neurons with the potential for therapeutic compensation

    New caribou from the Cassiar Mts., B.C.

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    p. 149-158 : ill. ; 24 cm.Includes bibliographical references
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