9 research outputs found

    Biometric identity-based cryptography for e-Government environment

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    Government information is a vital asset that must be kept in a trusted environment and efficiently managed by authorised parties. Even though e-Government provides a number of advantages, it also introduces a range of new security risks. Sharing confidential and top-secret information in a secure manner among government sectors tend to be the main element that government agencies look for. Thus, developing an effective methodology is essential and it is a key factor for e-Government success. The proposed e-Government scheme in this paper is a combination of identity-based encryption and biometric technology. This new scheme can effectively improve the security in authentication systems, which provides a reliable identity with a high degree of assurance. In addition, this paper demonstrates the feasibility of using Finite-state machines as a formal method to analyse the proposed protocols

    Analysis of security protocols using finite-state machines

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    This paper demonstrates a comprehensive analysis method using formal methods such as finite-state machine. First, we describe the modified version of our new protocol and briefly explain the encrypt-then-authenticate mechanism, which is regarded as more a secure mechanism than the one used in our protocol. Then, we use a finite-state verification to study the behaviour of each machine created for each phase of the protocol and examine their behaviour s together. Modelling with finite-state machines shows that the modified protocol can function correctly and behave properly even with invalid input or time delay

    Modelling and simulation of a biometric identity-based cryptography

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    Government information is a vital asset that must be kept in a trusted environment and efficiently managed by authorised parties. Even though e-Government provides a number of advantages, it also introduces a range of new security risks. Sharing confidential and top-secret information in a secure manner among government sectors tend to be the main element that government agencies look for. Thus, developing an effective methodology is essential and it is a key factor for e-Government success. The proposed e-Government scheme in this paper is a combination of identity-based encryption and biometric technology. This new scheme can effectively improve the security in authentication systems, which provides a reliable identity with a high degree of assurance. In addition, this paper demonstrates the feasibility of using Finite-state machines as a formal method to analyse the proposed protocols

    A new biometric ID-based cryptography protocol and security analysis using Petri nets

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    This paper presents a Petri net (PN) approach to modelling, simulating, and analysing the new protocol we have proposed. This new protocol is an enhanced authentication scheme based on a biometric verification mechanism and identity based cryptography. A formal approach like Petri nets allows one to represent cryptographic protocols. For the sake of simplicity, a complex PN model will not be discussed in this paper until all attacks are demonstrated and the model proved to be secure. This paper shows how Petri nets are used to model, analyse and detect flaws in our new protocol. First, our proposed protocol is modelled without an adversary, and then a generic adversary model is added to examine all possible adversary behaviours. Finally we demonstrate how Petri nets can be used to analyse security threats such as man-in-the-middle attack, reflection attack, and parallel session attack on this protocol

    Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis

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    Sphingomyelinases generate ceramide from sphingomyelin as a second messenger in intracellular signaling pathways involved in cell proliferation, differentiation, or apoptosis. Children from 12 unrelated families presented with microcephaly, simplified gyral pattern of the cortex, hypomyelination, cerebellar hypoplasia, congenital arthrogryposis, and early fetal/postnatal demise. Genomic analysis revealed bi-allelic loss-of-function variants in SMPD4, coding for the neutral sphingomyelinase-3 (nSMase-3/SMPD4). Overexpression of human Myc-tagged SMPD4 showed localization both to the outer nuclear envelope and the ER and additionally revealed interactions with several nuclear pore complex proteins by proteomics analysis. Fibroblasts from affected individuals showed ER cisternae abnormalities, suspected for increased autophagy, and were more susceptible to apoptosis under stress conditions, while treatment with siSMPD4 caused delayed cell cycle progression. Our data show that SMPD4 links homeostasis of membrane sphingolipids to cell fate by regulating the cross-talk between the ER and the outer nuclear envelope, while its loss reveals a pathogenic mechanism in microcephaly

    Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis

    No full text
    Sphingomyelinases generate ceramide from sphingomyelin as a second messenger in intracellular signaling pathways involved in cell proliferation, differentiation, or apoptosis. Children from 12 unrelated families presented with microcephaly, simplified gyral pattern of the cortex, hypomyelination, cerebellar hypoplasia, congenital arthrogryposis, and early fetal/postnatal demise. Genomic analysis revealed bi-allelic loss-of-function variants in SMPD4, coding for the neutral sphingomyelinase-3 (nSMase-3/SMPD4). Overexpression of human Myc-tagged SMPD4 showed localization both to the outer nuclear envelope and the ER and additionally revealed interactions with several nuclear pore complex proteins by proteomics analysis. Fibroblasts from affected individuals showed ER cisternae abnormalities, suspected for increased autophagy, and were more susceptible to apoptosis under stress conditions, while treatment with siSMPD4 caused delayed cell cycle progression. Our data show that SMPD4 links homeostasis of membrane sphingolipids to cell fate by regulating the cross-talk between the ER and the outer nuclear envelope, while its loss reveals a pathogenic mechanism in microcephaly
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