58 research outputs found
Developing an Embedded Model for Test suite prioritization process to optimize consistency rules for inconsistencies detection and model changes
Software form typically contains a lot of contradiction and uniformity checkers help engineers find them. Even if engineers are willing to tolerate inconsistencies, they are better off knowing about their existence to avoid follow-on errors and unnecessary rework. However, current approaches do not detect or track inconsistencies fast enough. This paper presents an automated approach for detecting and tracking inconsistencies in real time (while the model changes). Engineers only need to define consistency rules-in any language-and our approach automatically identifies how model changes affect these consistency rules. It does this by observing the behavior of consistency rules to understand how they affect the model. The approach is quick, correct, scalable, fully automated, and easy to use as it does not require any special skills from the engineers using it. We use this model to define generic prioritization criteria that are applicable to GUI, Web applications and Embedded Model. We evolve the model and use it to develop a unified theory. Within the context of this model, we develop and empirically evaluate several prioritization criteria and apply them to four stand-alone GUI and three Web-based applications, their existing test suites and mainly embedded systems. In this model we only run our data collection and test suite prioritization process on seven programs and their existing test suites. An experiment that would be more readily generalized would include multiple programs of different sizes and from different domains. We may conduct additional empirical studies with larger EDS to address this threat each test case has a uniform cost of running (processor time) monitoring (human time); these assumptions may not hold in practice. Second, we assume that each fault contributes uniformly to the overall cost, which again may not hold in practice
Immunoinformatics and Computer-Aided Drug Design as New Approaches against Emerging and Re-Emerging Infectious Diseases
Infectious diseases are initiated by small pathogenic living germs that are transferred from person to person by direct or indirect contact. Recently, different newly emerging and reemerging infectious viral diseases have become greater threats to human health and global stability. Investigators can anticipate epidemics through the advent of numerous mathematical tools that can predict specific pathogens and identify potential targets for vaccine and drug design and will help to fight against these challenges. Currently, computational approaches that include mathematical and essential tools have unfolded the way for a better understanding of newly originated emerging and re-emerging infectious disease, pathogenesis, diagnosis, and treatment option of specific diseases more easily, where immunoinformatics plays a crucial role in the discovery of novel peptides and vaccine candidates against the different viruses within a short time. Computational approaches include immunoinformatics, and computer-aided drug design (CADD)-based model trained biomolecules that offered reasonable and quick implementation approaches for the modern discovery of effective viral therapies. The essence of this review is to give insight into the multiple approaches not only for the detection of infectious diseases but also profound how people can pick appropriate models for the detection of viral therapeutics through computational approaches
NEW INSIGHT INTO THE MIDDLE EOCENE CALCAREOUS NANNOPLANKTON BIOSTRATIGRAPHY AND PALEOENVIRONMENT FROM FAYOUM AND BENI SUEF AREAS, EGYPT
The present study deals with calcareous nannoplankton paleoenvironmental and biostratigraphic implications as well as the genesis and the stratigraphic significance of an event bed recognized from the middle Eocene Beni Suef Formation in the sections of Gebel Na’alun (Fayoum area) and Gebel Homret Shaibun (Beni Suef area), Egypt. Calcareous nannoplankton biostratigraphy indicates that the Beni Suef Formation in the two areas is synchronous, covering an interval that may be correlated with the calcareous nannoplankton Zone NP17. Paleoenvironmental implications from calcareous nannoplankton suggests deposition of sediments in the Beni Suef Formation under relatively stable, temperate and mesotrophic conditions, with a short interval of eutrophication in the basal part of the Homret Shaibun section
Clinical Laboratory Test And Radiological Methods In Diagnosis Of Orthopedics Condition: Role Of Nurses In Facilitating These Procedures: Review
Despite the fact that the fields of radiological imaging, pathology, and laboratory analysis appear to be very different from one another, the medical diagnostic information that these sources provide has a great deal in common with one another. This information can be utilized effectively by encouraging the sharing of quantitative and qualitative results through the utilization of modern information technology processes. Developing the capacities of informatics to coordinate the analysis of pictures produced by clinical radiological imaging, anatomic cellular and molecular pathology, and data gained from the analysis of biomarkers in the laboratory; this method is based on the development of these capabilities. This skill helps to stimulate the formation of novel "integrated diagnostics" in orthopedic disorders, and nursing plays an important part in the technical aspects of many orthopedic operations
A revised Plio-Pleistocene age model and paleoceanography of the northeastern Caribbean Sea: IODP Site U1396 off Montserrat, Lesser Antilles
Site U1396 was piston cored as a part of Integrated Ocean Drilling Project Expedition 340 to establish a long record for Lesser Antilles volcanism. A ~150 m sediment succession was recovered from three holes on a bathymetric high ~33 km southwest of Montserrat. A series of shipboard and newly-generated chronostratigraphic tools (biostratigraphy, magnetostratigraphy, astrochronology, and stable isotope chemostratigraphy) were employed to generate an integrated age model. Two possible chronostratigraphic interpretations for the Brunhes chron are presented, with hypotheses to explain the discrepancies seen between this study and Wall-Palmer et al. (2014). The recent Wade et al. (2011) planktic foraminiferal biostratigraphic calibration is tested, revealing good agreement between primary datums observed at Site U1396 and calibrated ages, but significant mismatches for some secondary datums. Sedimentation rates are calculated, both including and excluding the contribution of discrete volcanic sediment layers within the succession. Rates are found to be ‘pulsed’ or highly variable within the Pliocene interval, declining through the 1.5-2.4 Ma interval, and then lower through the Pleistocene. Different explanations for the trends in the sedimentation rates are discussed, including orbitally-forced biogenic production spikes, elevated contributions of cryptotephra (dispersed ash), and changes in bottom water sources and flow rates with increased winnowing in the area of Site U1396 into the Pleistocene
A record of spontaneous subduction initiation in the Izu–Bonin–Mariana arc
The initiation of tectonic plate subduction into the mantle is poorly understood. If subduction is induced by the push of a distant mid-ocean ridge or subducted slab pull, we expect compression and uplift of the overriding plate. In contrast, spontaneous subduction initiation, driven by subsidence of dense lithosphere along faults adjacent to buoyant lithosphere, would result in extension and magmatism. The rock record of subduction initiation is typically obscured by younger deposits, so evaluating these possibilities has proved elusive. Here we analyse the geochemical characteristics of igneous basement rocks and overlying sediments, sampled from the Amami Sankaku Basin in the northwest Philippine Sea. The uppermost basement rocks are areally widespread and supplied via dykes. They are similar in composition and age—as constrained by the biostratigraphy of the overlying sediments—to the 52–48-million-year-old basalts in the adjacent Izu–Bonin–Mariana fore-arc. The geochemical characteristics of the basement lavas indicate that a component of subducted lithosphere was involved in their genesis, and the lavas were derived from mantle source rocks that were more melt-depleted than those tapped at mid-ocean ridges. We propose that the basement lavas formed during the inception of Izu–Bonin–Mariana subduction in a mode consistent with the spontaneous initiation of subduction
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Heat flow in the Lesser Antilles island arc and adjacent back arc Grenada basin
Using temperature gradients measured in 10 holes at 6 sites, we generate the first high fidelity heat flow measurements from Integrated Ocean Drilling Program drill holes across the northern and central Lesser Antilles arc and back arc Grenada basin. The implied heat flow, after correcting for bathymetry and sedimentation effects, ranges from about 0.1 W/m² on the crest of the arc, midway between the volcanic islands of Montserrat and Guadeloupe, to 15 km from the crest in the back arc direction. Combined with previous measurements, we find that the magnitude and spatial pattern of heat flow are similar to those at continental arcs. The heat flow in the Grenada basin to the west of the active arc is 0.06 W/m², a factor of 2 lower than that found in the previous and most recent study. There is no thermal evidence for significant shallow fluid advection at any of these sites. Present-day volcanism is confined to the region with the highest heat flow.American Geophysical Union – Geochemistry, Geophysics, Geosystems. This is the publisher’s final pdf. The published article is copyrighted by the American Geophysical Union and can be found at: http://www.agu.org/journals/gc/.Keywords: volcanic arc., Lesser Antilles, IODP, heat flow, back arc, Grenada basinKeywords: volcanic arc., Lesser Antilles, IODP, heat flow, back arc, Grenada basi
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Late Pleistocene stratigraphy of IODP Site U1396 and compiled chronology offshore of south and south west Montserrat, Lesser Antilles
Marine sediments around volcanic islands contain an archive of volcaniclastic deposits, which can be used to reconstruct the volcanic history of an area. Such records hold many advantages over often incomplete terrestrial data sets. This includes the potential for precise and continuous dating of intervening sediment packages, which allow a correlatable and temporally constrained stratigraphic framework to be constructed across multiple marine sediment cores. Here we discuss a marine record of eruptive and mass-wasting events spanning ~250 ka offshore of Montserrat, using new data from IODP Expedition 340, as well as previously collected cores. By using a combination of high-resolution oxygen isotope stratigraphy, AMS radiocarbon dating, biostratigraphy of foraminifera and calcareous nannofossils, and clast componentry, we identify five major events at Soufriere Hills volcano since 250 ka. Lateral correlations of these events across sediment cores collected offshore of the south and south west of Montserrat have improved our understanding of the timing, extent and associations between events in this area. Correlations reveal that powerful and potentially erosive density-currents traveled at least 33 km offshore and demonstrate that marine deposits, produced by eruption-fed and mass-wasting events on volcanic islands, are heterogeneous in their spatial distribution. Thus, multiple drilling/coring sites are needed to reconstruct the full chronostratigraphy of volcanic islands. This multidisciplinary study will be vital to interpreting the chaotic records of submarine landslides at other sites drilled during Expedition 340 and provides a framework that can be applied to the stratigraphic analysis of sediments surrounding other volcanic islands.Keywords: Debris avalanche, Pyroclastic flows, Late quaternary, Submarine evidenc
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