Ionized Gas Extended Over 40 kpc in an Odd Radio Circle Host Galaxy

A new class of extragalactic astronomical sources discovered in 2021, named Odd Radio Circles (ORCs, Norris et al. 2021), are large rings of faint, diffuse radio continuum emission spanning ~1 arcminute on the sky. Galaxies at the centers of several ORCs have photometric redshifts of z~0.3-0.6, implying physical scales of several 100 kiloparsecs in diameter for the radio emission, the origin of which is unknown. Here we report spectroscopic data on an ORC including strong [OII] emission tracing ionized gas in the central galaxy of ORC4 at z=0.4512. The physical extent of the [OII] emission is ~40 kpc in diameter, larger than expected for a typical early-type galaxy (Pandya et al, 2017) but an order of magnitude smaller than the large-scale radio continuum emission. We detect a ~200 km/s velocity gradient across the [OII] nebula, as well as a high velocity dispersion of ~180 km/s. The [OII] equivalent width (EW, ~50 Ang) is extremely high for a quiescent galaxy. The morphology, kinematics, and strength of the [OII] emission are consistent with the infall of shock ionized gas near the galaxy, following a larger-scale, outward moving shock driven by a galactic wind. Both the extended optical and radio emission, while observed on very different scales, may therefore result from the same dramatic event.Comment: 7 figures, accepted to Natur

Kinematics, Structure, and Mass Outflow Rates of Extreme Starburst Galactic Outflows

We present results on the properties of extreme gas outflows in massive ($\rm M_* \sim$10$^{11} \ \rm M_{\odot}$), compact, starburst ($\rm SFR \sim$$200 \, \rm M_{\odot} \ yr^{-1}$) galaxies at z = $0.4-0.7$ with very high star formation surface densities ($\rm \Sigma_{SFR} \sim$$2000 \,\rm M_{\odot} \ yr^{-1} \ kpc^{-2}$). Using optical Keck/HIRES spectroscopy of 14 HizEA starburst galaxies we identify outflows with maximum velocities of$820 - 2860 \kmps. High-resolution spectroscopy allows us to measure precise column densities and covering fractions as a function of outflow velocity and characterize the kinematics and structure of the cool gas outflow phase (T \sim$10$^4 K). We find substantial variation in the absorption profiles, which likely reflects the complex morphology of inhomogeneously-distributed, clumpy gas and the intricacy of the turbulent mixing layers between the cold and hot outflow phases. There is not a straightforward correlation between the bursts in the galaxies' star formation histories and their wind absorption line profiles, as might naively be expected for starburst-driven winds. The lack of strong \mgii \ absorption at the systemic velocity is likely an orientation effect, where the observations are down the axis of a blowout. We infer high mass outflow rates of \rm \sim$50$-$2200$\rm M_{\odot} \, yr^{-1}$, assuming a fiducial outflow size of 5 kpc, and mass loading factors of$\eta\sim$5 for most of the sample.$\eta\sim$20 for two galaxies. While these values have high uncertainties, they suggest that starburst galaxies are capable of ejecting very large amounts of cool gas that will substantially impact their future evolution.Comment: Accepted for publication in The Astrophysical Journa

The Space Density of Intermediate-redshift, Extremely Compact, Massive Starburst Galaxies

© 2022. The Author(s). Published by the American Astronomical Society. This is an open access article distributed under the Creative Commons Attribution License, to view a copy of the license, see: https://creativecommons.org/licenses/by/4.0/https://creativecommons.org/licenses/by/4.0/We present a measurement of the intrinsic space density of intermediate-redshift (z ∼ 0.5), massive (M * ∼ 1011 M ⊙), compact (R e ∼ 100 pc) starburst (ΣSFR ∼ 1000 M ⊙ yr−1 kpc−1) galaxies with tidal features indicative of them having undergone recent major mergers. A subset of them host kiloparsec-scale, > 1000 km s−1 outflows and have little indication of AGN activity, suggesting that extreme star formation can be a primary driver of large-scale feedback. The aim for this paper is to calculate their space density so we can place them in a better cosmological context. We do this by empirically modeling the stellar populations of massive, compact starburst galaxies. We determine the average timescale on which galaxies that have recently undergone an extreme nuclear starburst would be targeted and included in our spectroscopically selected sample. We find that massive, compact starburst galaxies targeted by our criteria would be selectable for ∼148−24+27 Myr and have an intrinsic space density nCS∼(1.1−0.3+0.5)×10−6Mpc−3 . This space density is broadly consistent with our z ∼ 0.5 compact starbursts being the most extremely compact and star-forming low-redshift analogs of the compact star-forming galaxies in the early universe, as well as them being the progenitors to a fraction of intermediate-redshift, post-starburst, and compact quiescent galaxies.Peer reviewe

The Ionization and Dynamics of the Makani Galactic Wind

© 2023 The Author(s). Published by the American Astronomical Society. This is an open access article distributed under the Creative Commons Attribution License, to view a copy of the license, see: https://creativecommons.org/licenses/by/4.0/The Makani galaxy hosts the poster child of a galactic wind on scales of the circumgalactic medium. It consists of a two-episode wind in which the slow, outer wind originated 400 Myr ago (Episode I; R I = 20 − 50 kpc) and the fast, inner wind is 7 Myr old (Episode II; R II = 0 − 20 kpc). While this wind contains ionized, neutral, and molecular gas, the physical state and mass of the most extended phase—the warm, ionized gas—are unknown. Here we present Keck optical spectra of the Makani outflow. These allow us to detect hydrogen lines out to r = 30–40 kpc and thus constrain the mass, momentum, and energy in the wind. Many collisionally excited lines are detected throughout the wind, and their line ratios are consistent with 200–400 km s−1 shocks that power the ionized gas, with v shock = σ wind. Combining shock models, density-sensitive line ratios, and mass and velocity measurements, we estimate that the ionized mass and outflow rate in the Episode II wind could be as high as those of the molecular gas: MIIHII∼MIIH2=(1−2)×109M⊙ and dM/dtIIHII∼dM/dtIIH2=170−250M⊙ yr−1. The outer wind has slowed, so that dM/dtIHII∼10M⊙ yr−1, but it contains more ionized gas, MIHII=5×109 M ⊙. The momentum and energy in the recent Episode II wind imply a momentum-driven flow (p “boost” ∼7) driven by the hot ejecta and radiation pressure from the Eddington-limited, compact starburst. Much of the energy and momentum in the older Episode I wind may reside in a hotter phase, or lie further into the circumgalactic medium.Peer reviewe

Physical Properties of Massive Compact Starburst Galaxies with Extreme Outflows

© 2021. The Author(s). Published by the American Astronomical Society. This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 licence. https://creativecommons.org/licenses/by/4.0/We present results on the nature of extreme ejective feedback episodes and the physical conditions of a population of massive (M * ∼ 1011 M ⊙), compact starburst galaxies at z = 0.4–0.7. We use data from Keck/NIRSPEC, SDSS, Gemini/GMOS, MMT, and Magellan/MagE to measure rest-frame optical and near-IR spectra of 14 starburst galaxies with extremely high star formation rate surface densities (mean ΣSFR ∼ 2000 M ⊙ yr−1 kpc−2) and powerful galactic outflows (maximum speeds v 98 ∼ 1000–3000 km s−1). Our unique data set includes an ensemble of both emission ([O ii] λλ3726,3729, Hβ, [O iii] λλ4959,5007, Hα, [N ii] λλ6549,6585, and [S ii] λλ6716,6731) and absorption (Mg ii λλ2796,2803, and Fe ii λ2586) lines that allow us to investigate the kinematics of the cool gas phase (T ∼ 104 K) in the outflows. Employing a suite of line ratio diagnostic diagrams, we find that the central starbursts are characterized by high electron densities (median n e ∼ 530 cm−3), and high metallicity (solar or supersolar). We show that the outflows are most likely driven by stellar feedback emerging from the extreme central starburst, rather than by an AGN. We also present multiple intriguing observational signatures suggesting that these galaxies may have substantial Lyman continuum (LyC) photon leakage, including weak [S ii] nebular emission lines. Our results imply that these galaxies may be captured in a short-lived phase of extreme star formation and feedback where much of their gas is violently blown out by powerful outflows that open up channels for LyC photons to escape.Peer reviewedFinal Published versio

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum

Microbial Reprogramming Inhibits Western Diet-Associated Obesity

A recent epidemiological study showed that eating ‘fast food’ items such as potato chips increased likelihood of obesity, whereas eating yogurt prevented age-associated weight gain in humans. It was demonstrated previously in animal models of obesity that the immune system plays a critical role in this process. Here we examined human subjects and mouse models consuming Westernized ‘fast food’ diet, and found CD4[superscript +] T helper (Th)17-biased immunity and changes in microbial communities and abdominal fat with obesity after eating the Western chow. In striking contrast, eating probiotic yogurt together with Western chow inhibited age-associated weight gain. We went on to test whether a bacteria found in yogurt may serve to lessen fat pathology by using purified Lactobacillus reuteri ATCC 6475 in drinking water. Surprisingly, we discovered that oral L. reuteri therapy alone was sufficient to change the pro-inflammatory immune cell profile and prevent abdominal fat pathology and age-associated weight gain in mice regardless of their baseline diet. These beneficial microbe effects were transferable into naïve recipient animals by purified CD4[superscript +] T cells alone. Specifically, bacterial effects depended upon active immune tolerance by induction of Foxp3[superscript +] regulatory T cells (Treg) and interleukin (Il)-10, without significantly changing the gut microbial ecology or reducing ad libitum caloric intake. Our finding that microbial targeting restored CD4[superscript +] T cell balance and yielded significantly leaner animals regardless of their dietary ‘fast food’ indiscretions suggests population-based approaches for weight management and enhancing public health in industrialized societies.National Institutes of Health (U.S.) (Grant P30-ES002109)National Institutes of Health (U.S.) (Grant RO1CA108854)National Institutes of Health (U.S.) (Grant P01 AI045757)National Institutes of Health (U.S.) (Grant U19 AI046130)National Institutes of Health (U.S.) (Grant U19 AI070352)National Institutes of Health (U.S.) (Grant P01 AI039671)National Institute of Neurological Disorders and Stroke (U.S.) (Jacob Javits Merit Award NS2427)The Penates FoundationNancy Taylor Foundation for Chronic Diseases, Inc

CRISPR/Cas9-targeted enrichment and long-read sequencing of the Fuchs endothelial corneal dystrophy–associated TCF4 triplet repeat

PURPOSE: To demonstrate the utility of an amplification-free long-read sequencing method to characterize the Fuchs endothelial corneal dystrophy (FECD)-associated intronic TCF4 triplet repeat (CTG18.1). METHODS: We applied an amplification-free method, utilizing the CRISPR/Cas9 system, in combination with PacBio single-molecule real-time (SMRT) long-read sequencing, to study CTG18.1. FECD patient samples displaying a diverse range of CTG18.1 allele lengths and zygosity status (n = 11) were analyzed. A robust data analysis pipeline was developed to effectively filter, align, and interrogate CTG18.1-specific reads. All results were compared with conventional polymerase chain reaction (PCR)-based fragment analysis. RESULTS: CRISPR-guided SMRT sequencing of CTG18.1 provided accurate genotyping information for all samples and phasing was possible for 18/22 alleles sequenced. Repeat length instability was observed for all expanded (≥50 repeats) phased CTG18.1 alleles analyzed. Furthermore, higher levels of repeat instability were associated with increased CTG18.1 allele length (mode length ≥91 repeats) indicating that expanded alleles behave dynamically. CONCLUSION: CRISPR-guided SMRT sequencing of CTG18.1 has revealed novel insights into CTG18.1 length instability. Furthermore, this study provides a framework to improve the molecular diagnostic accuracy for CTG18.1-mediated FECD, which we anticipate will become increasingly important as gene-directed therapies are developed for this common age-related and sight threatening disease