64 research outputs found

    AQUISIÇÃO DE PORTUGUÊS (ESCRITO) COMO SEGUNDA LÍNGUA POR SURDOS: RESULTADOS DA PESQUISA LINGUÍSTICA E IMPLICAÇÕES EDUCACIONAIS

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    Neste estudo, temos por objetivo investigar aspectos da situação linguística dos surdos, tendo em vista a relevância da educação linguística para sua socialização no âmbito da comunidade surda, por meio da língua de sinais brasileira (LSB), e com os ouvintes, por meio do português (escrito), adquirido como segunda língua. Nesse contexto, surgem questões políticas e científicas, que propiciam, por um lado, avanços sociais e institucionais e, por outro, a ampliação do conhecimento científico, particularmente em relação à Língua de Sinais Brasileira (LSB), na relação com outras línguas naturais. Adotando o quadro teórico da gramática gerativa, apresentamos resultados de pesquisas prévias em relação ao tema da aquisição de português como segunda língua por surdos em contexto educacional, demonstrando a eficácia da hipótese da interferência da L1, bem como o papel do aporte da interpretabilidade dos traços formais no desenvolvimento linguístico

    Intrahost Diversity of Feline Coronavirus: A Consensus between the Circulating Virulent/Avirulent Strains and the Internal Mutation Hypotheses?

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    To evaluate the most controversial issue concerning current feline coronavirus (FCoV) virology, the coexisting hypotheses of the intrahost and interhost origins of feline infectious peritonitis virus (FIPV) in regard to the pathogenesis of feline infectious peritonitis (FIP), this study aimed to assess the molecular diversity of the membrane gene FCoVs in 190 samples from 10 cats with signs of FIP and in 5 faecal samples from cats without signs of FIP. All samples from the non-FIP cats and 25.26% of the samples from the FIP cats were positive for the FCoV membrane (M) gene. Mutations in this gene consisted of SNP changes randomly scattered among the sequences; few mutations resulted in amino acid changes. No geographic pattern was observed. Of the cats without FIP that harboured FECoV, the amino acid sequence identities for the M gene were 100% among cats (Cats 1–3) from the same cattery, and the overall sequence identity for the M gene was ≥91%. In one cat, two different lineages of FCoV, one enteric and one systemic, were found that segregated apart in the M gene tree. In conclusion, the in vivo mutation transition hypothesis and the circulating high virulent-low virulent FCoV hypothesis have been found to be plausible according to the results obtained from sequencing the M gene

    Supplementation of carotenoids from peach palm waste (Bactris gasipaes) obtained with an ionic liquid mediated process displays kidney anti-inflammatory and antioxidant outcomes

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    Sustainable extraction processes based on alternative solvents to recover bioactive compounds of different raw materials have been highlighted as excellent alternatives to supply the needs of society towards a bioeconomy strategy. Little is known about the safety and biological effect of compounds extracted by these processes. In this work, carotenoids from Bactris gasipaes wastes obtained by an IL-based process were investigated in terms of safety, anti-inflammatory and, antioxidant activity in a high-fat-diet animal model on the kidney. Wistar rats were supplemented or not by carotenoids extracted with IL or VOS. The animals supplemented with carotenoids had lower weight than control and high-fat diets. In the animals supplemented with carotenoids, the group IL improved anti-inflammatory and antioxidant activity compared with carotenoids obtained by VOS. Also, the group HFD-VOS showed moderate-severe injuries on the kidney. Then, ILs could represent a novel tool for natural pigments safely applied to food industry.publishe
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