Investigating the Impact of Offering Statistics on Students Success

This article describes the author’s experience in developing and teaching an undergraduate course on Statistics for Industrial Engineering Technology (IET) students. Moreover, the impact of offering the course on students’ success in future courses for which Statistics is a pre-requisite, is discussed. The motivation to offer the course is twofold: 1) Statistics is a subject required by various programs and although several sections are being offered, often IET students would not be able to register in the course and consequently, they have to wait for next semester. 2) Since the Mathematics Department caters to students coming from various majors, the topics and particularly, examples and problems would not be necessarily major-oriented. In addition, the course has been offered since spring of 2012 and the degree to which the topics covered have addressed students need and faculty expectation are unknown. In this article, the author first describes the details of how the course was developed, how it would address relevant ABET’s accreditation criteria, and how it has been taught since spring of 2012 in terms contents. Then, the results of inquiry from faculty members in the department, as well as a summary of the course evaluations is presented. Finally, future modification to improve the course contents is mentioned

The Determination of Failure Occurring in the Stator Coil Winding due to the Over-Voltage using MATLAB Software

A thesis presented to the faculty of the College of Science & Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Vocational Education / Technology by Ali Reza Alavizadeh on January 8, 2001

The Determination of Failure Occurring in the Stator Coil Winding due to the Over-Voltage using MATLAB Software

A thesis presented to the faculty of the College of Science & Technology at Morehead State University in partial fulfillment of the requirements for the degree of Master of Science in Vocational Education & Technology by Ali Reza Alavizadeh on December 1, 2000

Lifetime Prevalence of Psychiatric Disorders among Parents of Children with Bipolar I Disorder: Parental Difference

Background. Evaluation of family system is an important area in the context of child and adolescent mental health. This study aimed to estimate psychiatric disorders in parents of children and adolescents with bipolar I disorder (BID). Methods and Materials. In this cross-sectional study, during 2012-2013, all of the children and adolescents diagnosed with BID based on Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version were included. All of the parents (both mother and father) were evaluated by Structured Clinical Interview for DSM-IV-TR. Statistical Analysis. Prevalence rates are reported and independentsample t-test and chi-square test were used when appropriate. Results. A total of 108 families were interviewed. 25% of mothers and 33% of fathers met the criteria for at least one psychiatric disorder, with major depressive disorder, BMD, and cluster B personality disorder being more prevalent. Fathers were more likely to receive a dual psychiatric diagnosis. Cluster B personality disorder and substance dependence were more prevalent among fathers while major depressive disorder was more prevalent among mothers. Conclusion. This study confirmed a higher prevalence of psychiatric disorders in parents of children with BID and emphasizes parental evolution

Common Aeroallergens in Patients with Asthma and Allergic Rhinitis Living in Southwestern Part of Iran: Based on Skin Prick Test Reactivity

Aeroallergens continue to have a key role in the pathogenesis of asthma and allergic diseases and have recently received increased attention in medical research throughout the world. The prevalence of aeroallergens vary in different regions, depending on the type of climate. The aim of the present study was to determine prevalence of the sensitivity to aeroallergens among patients with asthma and allergic rhinitis (AR), based on skin prick test (SPT) reactivity in the province of Bushehr, Iran. In this cross-sectional study, 743 patients were enrolled. The participants had asthma and AR and reacted to at least one allergen with SPT. Skin prick test with standard extracts including house dust mites (HDMs), animal dander, molds and pollens were performed on patients according to the herbal geography of the area. The male to female ratio and mean age of the patients were 1.03 and 27.6± 15.4 year, respectively. Out of 567 patients with AR, the common aeroallergens were HDMs (88.5%), molds (82.9%), animal dander (79.5%), weeds (77.6%), trees (75.5%) and grass pollen (71.5%). Moreover, among 176 patients with asthma, the prevalence of aeroallergens were HDMs (90.5 %), molds (80.7%), animal dander (77.5%), weeds (73.3%), trees (73.3%) and grass pollen (67.9%). The sensitivity to animal dander, Chenopodium album and Russian thistle pollens were significantly associated with the severity of AR. Moreover, sensitivity to animal dander such as cat and feather of birds, cockroach, Bermuda grass and Chenopodium album pollens were significantly associated with the severity of asthma. The results of this study revealed that HDM was the most common sensitizing aeroallergen in patients with asthma and AR. Molds and animal dander as indoor allergens were also common aeroallergens. We suggest that the hot weather and ambient humidity in the region may be the main cause of the change in the pattern of SPT reactivity

Nanocarriers call the last shot in the treatment of brain cancers

Our brain is protected by physio-biological barriers. The blood–brain barrier (BBB) main mechanism of protection relates to the abundance of tight junctions (TJs) and efflux pumps. Although BBB is crucial for healthy brain protection against toxins, it also leads to failure in a devastating disease like brain cancer. Recently, nanocarriers have been shown to pass through the BBB and improve patients’ survival rates, thus becoming promising treatment strategies. Among nanocarriers, inorganic nanocarriers, solid lipid nanoparticles, liposomes, polymers, micelles, and dendrimers have reached clinical trials after delivering promising results in preclinical investigations. The size of these nanocarriers is between 10 and 1000 nm and is modified by surface attachment of proteins, peptides, antibodies, or surfactants. Multiple research groups have reported transcellular entrance as the main mechanism allowing for these nanocarriers to cross BBB. Transport proteins and transcellular lipophilic pathways exist in BBB for small and lipophilic molecules. Nanocarriers cannot enter via the paracellular route, which is limited to water-soluble agents due to the TJs and their small pore size. There are currently several nanocarriers in clinical trials for the treatment of brain cancer. This article reviews challenges as well as fitting attributes of nanocarriers for brain tumor treatment in preclinical and clinical studies

Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach

Objective(s): Brain cancer treatments have mainly failed due to their inability to cross the blood-brain barrier. Several studies have confirmed the presence of glutathione (GSH) receptors on BBB’s surface, as a result, products like 2B3-101, which contain over 5% pre-inserted GSH PEGylated liposomal Doxorubicin, are being tested in clinical trials. Here we conducted the PEGylated nanoliposomal Doxorubicin particles that are covalently attached to the glutathione using the post-insertion technique. Compared with the pre-insertion approach, the post-insertion method is notably simpler, faster, and more cost-effective, making it ideal for large-scale pharmaceutical manufacturing. Materials and Methods: The ligands of the DSPE PEG(2000) Maleimide-GSH were introduced in the amounts of 25, 50, 100, 200, and 400 on the available Caelyx. Following physicochemical evaluations, animal experiments such as biodistribution, fluorescence microscopy, and pharmacokinetics were done. Results: In comparison with Caelyx, the 200L and 400L treatment arms were the most promising formulations. We showed that nanocarriers containing 40 times fewer GSH micelles than 2B3-101 significantly increased blood-brain barrier penetrance. Due to the expressed GSH receptors on tissues as an endogenous antioxidant, Doxorubicin will likely concentrate in the liver, spleen, heart, and lung in comparison with Caelyx, according to other tissue analyses. Conclusion: The post-insertion technique was found a successful approach with more pharmaceutical aspects for large-scale production. Moreover, further investigations are highly recommended to determine the efficacy of 5% post-inserted GSH targeted nanoliposomes versus 2B3-101 as a similar formulation with a different preparation method

Structural Relationships Between Assertiveness and Parenting Styles With Mediating Self-esteem and Anxiety of Singleton Children

Objectives: This study aimed to develop an explanatory model of assertiveness based on parenting styles mediated by anxiety and self-esteem. Methods: This study is descriptive-correlational modeling with partial least squares. The statistical population included singleton children of the sixth grade of the elementary school in the 3rd District of Tehran in the academic year 2017-18. The sampling method was multi-stage sampling; eight schools (four all-boys and four all-girls) were randomly selected from all primary schools in the 3rd District of Tehran, then, a sixth-grade class was randomly selected in each school. The singleton students of those classes participated in the present study as the study sample. The sample size was 118 students (81 girls and 37 boys). The instruments of this research included the Persian forms of adaptive and aggressive assertiveness scales (AAA-S), the Baumrind parenting scale, Beck anxiety inventory (BAI), and Rosenberg self-esteem scale (RSES). To analyze the data, the SPSS software, version 26. Results: The results indicated that authoritative and permissive parenting styles had a significant effect on assertiveness among the parenting styles. The total effects indicated that authoritative and permissive parenting styles explained 0.22 and 0.20 of the variances of assertiveness. The results also showed that the authoritarian parenting style had no significant effect on assertiveness. Discussion: The suggested model was acceptably fit, according to the results of the study. Permissive and authoritative parenting styles had impact on assertiveness