27 research outputs found
Bostonia: The Boston University Alumni Magazine. Volume 12
Founded in 1900, Bostonia magazine is Boston University’s main alumni publication
SO(10) Cosmic Strings and SU(3) Color Cheshire Charge
Certain cosmic strings that occur in GUT models such as can carry a
magnetic flux which acts nontrivially on objects carrying
quantum numbers. We show that such strings are non-Abelian Alice strings
carrying nonlocalizable colored ``Cheshire" charge. We examine claims made in
the literature that strings can have a long-range, topological
Aharonov-Bohm interaction that turns quarks into leptons, and observe that such
a process is impossible. We also discuss flux-flux scattering using a
multi-sheeted formalism.Comment: 37 Pages, 8 Figures (available upon request) phyzzx, iassns-hep-93-6,
itp-sb-93-6
New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms
Background: Hyperekplexia mutations have provided much information about glycine receptor structure and function. Results: Weidentified and characterized nine new mutations. Dominant mutations resulted in spontaneous activation, whereas recessive mutations precluded surface expression. Conclusion: These data provide insight into glycine receptor activation mechanisms and surface expression determinants. Significance: The results enhance our understanding of hyperekplexia pathology and glycine receptor structure-function. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A