6 research outputs found
Parainfluenza-3 and bovine respiratory syncytial virus: intraherd correlation adjusted for sensitivity and specificity
ABSTRACT
Objective. The purpose of this study was to compare the intra-class correlation coefficients (ICC) and design effects (D) estimates adjusted or unadjusted for sensibility (Se) and specificity (Sp) of the diagnostic tests using a Bayesian procedure. Materials and methods. Sera from 232 animals from 44 randomly selected herds, to detect antibodies against parainfluenza-3 virus (PIV3) from non-vaccinated dual-purpose cattle from Colima Mexico, were used. Only 176 animals from 33 herds were used to evaluate the presence of the bovine respiratory syncytial virus (BRSV). Results. The ICC and D values adjusted and unadjusted for PIV3 were 0.33, 2.73, 0.32, and 2.71, respectively. For BRSV the values were 0.31, 2.64, 0.28 and 2.49. Conclusions. The adjusted or unadjusted ICC and D estimates were similar because of the high Se and Sp of the diagnostic tests and the relatively high prevalence of the diseases here studied
Parainfluenza-3 and bovine respiratory syncytial virus: intraherd correlation adjusted for sensitivity and specificity
Objetivo. El propósito de este estudio fue comparar los valores de los coeficientes de correlación
intraclase (ICC) y efecto de diseño (D) ajustados y no ajustados por la sensibilidad (Se) y especificidad
(Es) de la prueba de diagnóstico usando procedimientos bayesianos. Materiales y métodos. Se
utilizaron los sueros sanguíneos de 232 animales de 44 hatos seleccionados al azar, para detectar
anticuerpos contra el virus de la parainfluenza-3 (VPI3) en bovinos de doble propósito, no vacunados
en Colima, México. Se usaron 176 animales de 33 hatos para evaluar la presencia del virus respiratorio
sincitial bovino (VRSB) Resultados. Los valores ajustados y no ajustados de ICC y D para VPI3 fueron
0.33, 2.73, 0.32 y 2.71, respectivamente. Para VRSB los valores fueron 0.31, 2.64, 0.28 y 2.49.
Conclusiones. Los estimadores de ICC y D fueron similares debido a la alta Se y Es de las pruebas
de diagnóstico y a la relativa alta prevalencia de las enfermedades estudiadas.Objective. The purpose of this study was to compare the intra-class correlation coefficients (ICC)
and design effects (D) estimates adjusted or unadjusted for sensibility (Se) and specificity (Sp) of
the diagnostic tests using a Bayesian procedure. Materials and methods. Sera from 232 animals
from 44 randomly selected herds, to detect antibodies against parainfluenza-3 virus (PIV3) from
non-vaccinated dual-purpose cattle from Colima Mexico, were used. Only 176 animals from 33 herds
were used to evaluate the presence of the bovine respiratory syncytial virus (BRSV). Results. The
ICC and D values adjusted and unadjusted for PIV3 were 0.33, 2.73, 0.32, and 2.71, respectively.
For BRSV the values were 0.31, 2.64, 0.28 and 2.49. Conclusions. The adjusted or unadjusted ICC
and D estimates were similar because of the high Se and Sp of the diagnostic tests and the relatively
high prevalence of the diseases here studied