Parainfluenza-3 and bovine respiratory syncytial virus: intraherd correlation adjusted for sensitivity and specificity

ABSTRACT Objective. The purpose of this study was to compare the intra-class correlation coefficients (ICC) and design effects (D) estimates adjusted or unadjusted for sensibility (Se) and specificity (Sp) of the diagnostic tests using a Bayesian procedure. Materials and methods. Sera from 232 animals from 44 randomly selected herds, to detect antibodies against parainfluenza-3 virus (PIV3) from non-vaccinated dual-purpose cattle from Colima Mexico, were used. Only 176 animals from 33 herds were used to evaluate the presence of the bovine respiratory syncytial virus (BRSV). Results. The ICC and D values adjusted and unadjusted for PIV3 were 0.33, 2.73, 0.32, and 2.71, respectively. For BRSV the values were 0.31, 2.64, 0.28 and 2.49. Conclusions. The adjusted or unadjusted ICC and D estimates were similar because of the high Se and Sp of the diagnostic tests and the relatively high prevalence of the diseases here studied

The sphingidae of Chajul, Chiapas, Mexico

Volume: 52Start Page: 105End Page: 11

Parainfluenza-3 and bovine respiratory syncytial virus: intraherd correlation adjusted for sensitivity and specificity

Objetivo. El propósito de este estudio fue comparar los valores de los coeficientes de correlación intraclase (ICC) y efecto de diseño (D) ajustados y no ajustados por la sensibilidad (Se) y especificidad (Es) de la prueba de diagnóstico usando procedimientos bayesianos. Materiales y métodos. Se utilizaron los sueros sanguíneos de 232 animales de 44 hatos seleccionados al azar, para detectar anticuerpos contra el virus de la parainfluenza-3 (VPI3) en bovinos de doble propósito, no vacunados en Colima, México. Se usaron 176 animales de 33 hatos para evaluar la presencia del virus respiratorio sincitial bovino (VRSB) Resultados. Los valores ajustados y no ajustados de ICC y D para VPI3 fueron 0.33, 2.73, 0.32 y 2.71, respectivamente. Para VRSB los valores fueron 0.31, 2.64, 0.28 y 2.49. Conclusiones. Los estimadores de ICC y D fueron similares debido a la alta Se y Es de las pruebas de diagnóstico y a la relativa alta prevalencia de las enfermedades estudiadas.Objective. The purpose of this study was to compare the intra-class correlation coefficients (ICC) and design effects (D) estimates adjusted or unadjusted for sensibility (Se) and specificity (Sp) of the diagnostic tests using a Bayesian procedure. Materials and methods. Sera from 232 animals from 44 randomly selected herds, to detect antibodies against parainfluenza-3 virus (PIV3) from non-vaccinated dual-purpose cattle from Colima Mexico, were used. Only 176 animals from 33 herds were used to evaluate the presence of the bovine respiratory syncytial virus (BRSV). Results. The ICC and D values adjusted and unadjusted for PIV3 were 0.33, 2.73, 0.32, and 2.71, respectively. For BRSV the values were 0.31, 2.64, 0.28 and 2.49. Conclusions. The adjusted or unadjusted ICC and D estimates were similar because of the high Se and Sp of the diagnostic tests and the relatively high prevalence of the diseases here studied