405 research outputs found

    Putting an explanatory understanding into a predictive perspective: An exemplary study on school track enrollment

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    Complementing widely used explanatory models in the educational sciences that pinpoint the resources and characteristics for explaining students’ distinct educational transitions, this paper departs from methodological traditions and evaluates the predictive power of established concepts: to what extent can we actually predict school track enrollment based on a plethora of well-known explanatory factors derived from previous research? Predictive models were established using recursive partitioning adopted from machine learning. The basis for the analyses was the unique Zurich Learning Progress Study in Switzerland, a longitudinal study that followed a sample of 2000 students throughout compulsory education. This paper presents an exemplary examination of predictive modeling, and encourages educational sciences in general to explore beyond the horizon of their disciplinary methodological standards, which may help to consider the limits of an exclusive focus on explanatory approaches. The results provide an insight into the predictive capacity of well-established educational measures and concepts in predicting school track enrollment. The results show that there is quite a bit we cannot explain in educational navigation at the very end of elementary education. Yet, predictive misclassifications mainly occur between adjacent school tracks. Very few misclassifications in the future enrollment of academic-track and basic-track students, i.e., those pursuing the most- and least-prestigious tracks, respectively, occur

    Development of a new occupational balance-questionnaire: incorporating the perspectives of patients and healthy people in the design of a self-reported occupational balance outcome instrument

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    BACKGROUND: Self-reported outcome instruments in health research have become increasingly important over the last decades. Occupational therapy interventions often focus on occupational balance. However, instruments to measure occupational balance are scarce. The aim of the study was therefore to develop a generic self-reported outcome instrument to assess occupational balance based on the experiences of patients and healthy people including an examination of its psychometric properties. METHODS: We conducted a qualitative analysis of the life stories of 90 people with and without chronic autoimmune diseases to identify components of occupational balance. Based on these components, the Occupational Balance-Questionnaire (OB-Quest) was developed. Construct validity and internal consistency of the OB-Quest were examined in quantitative data. We used Rasch analyses to determine overall fit of the items to the Rasch model, person separation index and potential differential item functioning. Dimensionality testing was conducted by the use of t-tests and Cronbach’s alpha. RESULTS: The following components emerged from the qualitative analyses: challenging and relaxing activities, activities with acknowledgement by the individual and by the sociocultural context, impact of health condition on activities, involvement in stressful activities and fewer stressing activities, rest and sleep, variety of activities, adaptation of activities according to changed living conditions and activities intended to care for oneself and for others. Based on these, the seven items of the questionnaire (OB-Quest) were developed. 251 people (132 with rheumatoid arthritis, 43 with systematic lupus erythematous and 76 healthy) filled in the OB-Quest. Dimensionality testing indicated multidimensionality of the questionnaire (t = 0.58, and 1.66 after item reduction, non-significant). The item on the component rest and sleep showed differential item functioning (health condition and age). Person separation index was 0.51. Cronbach’s alpha changed from 0.38 to 0.57 after deleting two items. CONCLUSIONS: This questionnaire includes new items addressing components of occupational balance meaningful to patients and healthy people which have not been measured so far. The reduction of two items of the OB-Quest showed improved internal consistency. The multidimensionality of the questionnaire indicates the need for a summary of several components into subscales

    Initial evidence for the link between activities and health: associations between a balance of activities, functioning and serum levels of cytokines and C-reactive protein

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    AbstractGrowing evidence shows interrelations of psychological factors, neurological and immunological processes. Therefore, constructs like a balance of activities, the so called “occupational balance”, could also have biological correlates. The aim of this study was to investigate potential associations between occupational balance, functioning, cytokines and C-reactive protein (CRP) in patients suffering from a chronic inflammatory disease like rheumatoid arthritis (RA) and healthy people. Moreover, we wanted to explore potential differences in gender and employment status.A descriptive study in patients with RA and healthy people was conducted using the Occupational Balance-Questionnaire (OB-Quest) and the Short-Form 36 Health Survey (SF-36). Serum levels of cytokines, such as interleukin 6 (IL-6) and 8 (IL-8), interferon alpha (INFα), tumour necrosis factor alpha (TNFα), rheumatoid factor (RF) and of CRP were measured. Descriptive statistics, as well as Mann-Whitney U tests and Spearmen's rank correlation coefficients (rs) were calculated.One-hundred-thirty-two patients with RA and 76 healthy people participated. Occupational balance was associated with functioning, cytokines and CRP. The strongest associations were identified in the unemployed healthy-people sample with cytokines and CRP being within the normal range. For example, the OB-Quest item challenging activities was associated with IL-8 (rs=−0.63, p=0.04) and the SF-36 sub-scale bodily pain was associated with IFNα (rs=−0.69, p=0.02). The items rest and sleep (rs=−0.71, p=0.01) and variety of different activities (rs=−0.74, p<0.01) correlated with the SF-36 sub-scale social functioning. Employed and unemployed people differed in their age and CRP levels. Additionally, gender differences were found in two OB-Quest items in that fewer women were able to adapt their activities to changing living conditions and fewer men were overstressed. In conclusion, we found preliminary biological evidence for the link between occupation and health in that the concepts encompassed in the construct of occupational balance were associated with functioning, cytokines and CRP

    Prise en charge des syncopes aux urgences (un nouvel outil pour une meilleure orientation ?)

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    La syncope est un motif frĂ©quent de consultation aux urgences et d admission hospitaliĂšre. Il n existe pas d Ă©valuation standardisĂ©e concernant la prise en charge des syncopes. L objectif de notre Ă©tude Ă©tait de comparer l orientation aux urgences des patients admis pour syncopes sans et avec l utilisation d un logiciel d aide Ă  la dĂ©cision mĂ©dicale. Il s agissait d une Ă©tude observationnelle rĂ©trospective qui incluait les sujets adultes s Ă©tant prĂ©sentĂ©s aux urgences du CHU Grenoble pour malaise avec perte de connaissance entre le 1er janvier et le 31 mai 2011. Notre critĂšre de jugement principal Ă©tait qu il existait un faible accord entre l orientation des patients prise par les mĂ©decins des urgences et l orientation proposĂ©e par le logiciel. Parmi les 22297 patients ayant consultĂ© aux urgences, 1,36% avaient un diagnostic de syncope. Notre Ă©chantillon d Ă©tude portait sur 287 patients. A l issue de leur passage aux urgences, 147 patients sont rentrĂ©s Ă  domicile, 60 sont sortis avec la consigne de voir un spĂ©cialiste et 80 ont Ă©tĂ© hospitalisĂ©s. Les patients hospitalisĂ©s avaient un Ăąge mĂ©dian supĂ©rieur Ă  celui des patients rentrĂ©s Ă  domicile, avaient plus de facteurs de risque cardiovasculaire, avaient plus souvent une cardiopathie et un ECG anormal. Les orientations prĂ©conisĂ©es par le logiciel auraient Ă©tĂ© 155 retours Ă  domicile, 11 explorations complĂ©mentaires, 121 hospitalisations. L accord observĂ© entre l orientation des patients prise par le mĂ©decin des urgences et celle proposĂ©e par le logiciel Ă©tait de 56%, soit un accord modĂ©rĂ©. Le logiciel peut ĂȘtre une aide pour les mĂ©decins travaillant aux urgences mais ne se substitue pas Ă  leur jugement clinique.GRENOBLE1-BU MĂ©decine pharm. (385162101) / SudocSudocFranceF

    The Relationship Between Components of the Vegetarian Diet and Perceived Stress and Mental Distress

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    Recent evidence suggests that dietary patterns have an impact on mental health. However, little is known about how dietary patterns may impact the stress response. The purpose of this study was to investigate how components of a vegetarian diet relate to stress and mental distress. An anonymous survey was distributed primarily through social media targeting participants from diverse backgrounds. This study analyzed a total of 585 responses from adults 18 years old or older. Spearman’s rho correlation and principal component analysis were used to assess how dietary patterns and consumption of various foods and food groups relate to perceived stress and mental distress levels. The data was analyzed in SPSS version 25.0. Our results reveal a negative correlation between stress and whole grains (⍮= -0.103), dark green leafy vegetables (⍮= -0.154), and beans (⍮= -0.102). Mental distress was a negatively correlated with whole grains (⍮= -.147), nuts and flaxseed (⍮= -0.116), dark green leafy vegetables (⍮= -0.153), yogurt (⍮= -0.084), eggs (⍮= -0.108) and raw oats (⍮= -.101). These results indicate that multiple components of the vegetarian diet are inversely associated with stress, which explains the negative association with mental distress. Our results suggest that vegetarian items improve the stress response, which eventually improves mental health.https://orb.binghamton.edu/research_days_posters_2021/1101/thumbnail.jp

    Do patient-reported outcome measures cover personal factors important to people with rheumatoid arthritis? A mixed methods design using the International Classification of Functioning, Disability and Health as frame of reference

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    Background: Personal factors (PFs) are internal factors that determine functioning and the individuals' experience of disability. Their coverage by patient-reported outcome measures (PROMs) has not been examined in rheumatoid arthritis (RA) so far. The aims of this study were to identify PFs important in the life stories of people with RA and to determine their coverage by PROMs used in RA. Methods: The qualitative data of people with RA was explored to identify PFs. Additionally a systematic literature search was conducted to find PROMs used in RA. PROMs items were linked to the components, domains and categories of the International Classification of Functioning, Disability and Health (ICF) to determine the coverage of important PFs by PROMs. Results: Twelve PFs were found to be important in the life stories of people with RA. The PFs coping and reflecting about one's life in an optimistic way were covered most frequently, each by 14 of the 42 explored PROMs, while job satisfaction was not covered at all. The London Coping with Rheumatoid Arthritis Questionnaire, General Self-Efficacy Scale, Arthritis Self-Efficacy Scale, Rheumatoid Arthritis Self-Efficacy Questionnaire and Revised Ways of Coping Inventory covered most PFs. Nineteen PROMs did not cover any of the PFs. Conclusion: Several PFs were identified as important in the life stories of people with RA, but only 55% of the PROMS covered some of these PFs. When evaluating PFs important to people with RA, health professionals should be alert on which PROMs can be used to assess which PFs

    Do patient-reported outcome measures cover personal factors important to people with rheumatoid arthritis? A mixed methods design using the International Classification of Functioning, Disability and Health as frame of reference

    Get PDF
    Background: Personal factors (PFs) are internal factors that determine functioning and the individuals' experience of disability. Their coverage by patient-reported outcome measures (PROMs) has not been examined in rheumatoid arthritis (RA) so far. The aims of this study were to identify PFs important in the life stories of people with RA and to determine their coverage by PROMs used in RA. Methods: The qualitative data of people with RA was explored to identify PFs. Additionally a systematic literature search was conducted to find PROMs used in RA. PROMs items were linked to the components, domains and categories of the International Classification of Functioning, Disability and Health (ICF) to determine the coverage of important PFs by PROMs. Results: Twelve PFs were found to be important in the life stories of people with RA. The PFs coping and reflecting about one's life in an optimistic way were covered most frequently, each by 14 of the 42 explored PROMs, while job satisfaction was not covered at all. The London Coping with Rheumatoid Arthritis Questionnaire, General Self-Efficacy Scale, Arthritis Self-Efficacy Scale, Rheumatoid Arthritis Self-Efficacy Questionnaire and Revised Ways of Coping Inventory covered most PFs. Nineteen PROMs did not cover any of the PFs. Conclusion: Several PFs were identified as important in the life stories of people with RA, but only 55% of the PROMS covered some of these PFs. When evaluating PFs important to people with RA, health professionals should be alert on which PROMs can be used to assess which PFs

    Using person‐specific neural networks to characterize heterogeneity in eating disorders: Illustrative links between emotional eating and ovarian hormones

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    ObjectiveEmotional eating has been linked to ovarian hormone functioning, but no studies to‐date have considered the role of brain function. This knowledge gap may stem from methodological challenges: Data are heterogeneous, violating assumptions of homogeneity made by between‐subjects analyses. The primary aim of this paper is to describe an innovative within‐subjects analysis that models heterogeneity and has potential for filling knowledge gaps in eating disorder research. We illustrate its utility in an application to pilot neuroimaging, hormone, and emotional eating data across the menstrual cycle.MethodGroup iterative multiple model estimation (GIMME) is a person‐specific network approach for estimating sample‐, subgroup‐, and individual‐level connections between brain regions. To illustrate its potential for eating disorder research, we apply it to pilot data from 10 female twins (N = 5 pairs) discordant for emotional eating and/or anxiety, who provided two resting state fMRI scans and hormone assays. We then demonstrate how the multimodal data can be linked in multilevel models.ResultsGIMME generated person‐specific neural networks that contained connections common across the sample, shared between co‐twins, and unique to individuals. Illustrative analyses revealed positive relations between hormones and default mode connectivity strength for control twins, but no relations for their co‐twins who engage in emotional eating or who had anxiety.DiscussionThis paper showcases the value of person‐specific neuroimaging network analysis and its multimodal associations in the study of heterogeneous biopsychosocial phenomena, such as eating behavior.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146371/1/eat22902.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146371/2/eat22902_am.pd

    Using Water Chemistry, Isotopes and Microbiology to Evaluate Groundwater Sources, Flow Paths and Geochemical Reactions in the Death Valley Flow System, USA

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    AbstractSprings of Ash Meadows and Furnace Creek (near or in Death Valley, CA) have nearly constant flow, temperature, chemistry, and similar ÎŽ2H and ÎŽ18O signatures. These factors indicate shared water sources and/or analogous geochemical reactions along similar flow paths. DNA-based (16S rRNA gene) microbial diversity assessments further illuminate these relationships. Whereas, all Ash Meadows springs share related archaeal populations, variations in carbon-14 (Crystal Spring) and strontium isotopes, Na+, SO2-, and methane concentrations (Big Spring), correspond with microbial differences within and between the two discharge areas. Similar geochemical signatures linking Ash Meadows and Furnace Creek springs appear to support a distinct end member at Big Spring in Ash Meadows, which is also supported by coincident enrichment in microbial methanogens and methanotrophs. Conversely, DNA libraries from a deep carbonate well (878 m) located between Ash Meadows and Furnace Creek (BLM-1), indicate no shared microbial diversity between Ash Meadows or Furnace Creek springs
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