Constant current load matches impedances of electronic components

Constant current load with negative resistance characteristics actively compensates for impedance variations in circuit components. Through a current-voltage balancing operation the internal impedance of the diodes is maintained at a constant value. This constant current load circuit can be used in simple telemetry systems

Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs

Previous studies suggested the expression of mRNA, coding for CNP, exclusively in the central nervous system. In the present study, using the polymerase chain reaction (PCR) technique instead of the less sensitive Northern blot hybridization, CNP-specific sequences have also been detected in rat atria and ventricles of the heart as well as in organs of the immune system (thymus, spleen and lymph nodes). Parallel PCR-assays documented ANP-mRNA in these tissues. To verify specificity of the PCR-products, Southern blots have been hybridized with a third internal oligonucleotide and amplification products have been sequenced. The relative level of CNP-mRNA in these tissues was estimated to be in the range of 1-9% of total brain CNP transcripts. The results suggest that the peptide may have a peripheral as well as a central site of action. In light of its pronounced effect on cell proliferation, particular interest should focus on a possible role of CNP in the immune system

Continuous time volatility modelling: COGARCH versus Ornstein-Uhlenbeck models

We compare the probabilistic properties of the non-Gaussian Ornstein-Uhlenbeck based stochastic volatility model of Barndorff-Nielsen and Shephard (2001) with those of the COGARCH process. The latter is a continuous time GARCH process introduced by the authors (2004). Many features are shown to be shared by both processes, but differences are pointed out as well. Furthermore, it is shown that the COGARCH process has Pareto like tails under weak regularity conditions

A Continuous Time GARCH Process Driven by a Lévy Process: Stationarity and Second Order Behaviour

We use a discrete time analysis, giving necessary and sufficient conditions for the almost sure convergence of ARCH(1) and GARCH(1,1) discrete time models, tosuggest an extension of the (G)ARCH concept to continuous time processes. Our "COGARCH" (continuous time GARCH) model, based on a single background driving Levy process, is different from, though related to, other continuous time stochastic volatility models that have been proposed. The model generalises the essential features of discrete time GARCH processes, and is amenable to further analysis, possessing useful Markovian and stationarity properties

Optimization of thrust algorithm calibration for Computing System (TCS) for Thrust the NASA Highly Maneuverable Aircraft Technology (HiMAT) vehicle's propulsion system

A simplified gross thrust computing technique for the HiMAT J85-GE-21 engine using altitude facility data was evaluated. The results over the full engine envelope for both the standard engine mode and the open nozzle engine mode are presented. Results using afterburner casing static pressure taps are compared to those using liner static pressure taps. It is found that the technique is very accurate for both the standard and open nozzle engine modes. The difference in the algorithm accuracy for a calibration based on data from one test condition was small compared to a calibration based on data from all of the test conditions

SINGLE SPECIES VERSUS MULTIPLE SPECIES MODELS: THE ECONOMIC IMPLICATIONS

Ecologists frequently note the importance of modelling entire ecosystems rather than single species, but most bioeconomic models in the current literature focus on a single species. While the mathematical difficulty of multiple species may quickly become overwhelming, sometimes making the single species option necessary, it is important to recognise the significance of the single species assumption to the model results. In this paper, the authors address the economic significance of this assumption through the development of a multiple species model and demonstrate the importance of interrelationships and economic values to the survival of endangered species.Resource /Energy Economics and Policy,

Analytic expression for Taylor-Couette stability boundary

We analyze the mechanism that determines the boundary of stability in Taylor-Couette flow. By simple physical argument we derive an analytic expression to approximate the stability line for all radius ratios and all speed ratios, for co- and counterrotating cylinders. The expression includes viscosity and so generalizes Rayleigh's criterion. We achieve agreement with linear stability theory and with experiments in the whole parameter space. Explicit formulae are given for limiting cases.Comment: 6 pages (LaTeX with REVTEX) including 4 figures (Postscript) Revised, discussion of two additional references. See also http://staff-www.uni-marburg.de/~esse

Continuous breakdown of Purcell's scallop theorem with inertia

Purcell's scallop theorem defines the type of motions of a solid body - reciprocal motions - which cannot propel the body in a viscous fluid with zero Reynolds number. For example, the flapping of a wing is reciprocal and, as was recently shown, can lead to directed motion only if its frequency Reynolds number, Re_f, is above a critical value of order one. Using elementary examples, we show the existence of oscillatory reciprocal motions which are effective for all arbitrarily small values of the frequency Reynolds number and induce net velocities scaling as (Re_f)^\alpha (alpha > 0). This demonstrates a continuous breakdown of the scallop theorem with inertia.Comment: 6 pages, 1 figur

The Unusual Substrate Specificity of a Virulence Associated Serine Hydrolase from the Highly Toxic Bacterium, \u3cem\u3eFrancisella tularensis\u3c/em\u3e

Francisella tularensis is the causative agent of the highly, infectious disease, tularemia. Amongst the genes identified as essential to the virulence of F. tularensis was the proposed serine hydrolase FTT0941c. Herein, we purified FTT0941c to homogeneity and then characterized the folded stability, enzymatic activity, and substrate specificity of FTT0941c. Based on phylogenetic analysis, FTT0941c was classified within a divergent Francisella subbranch of the bacterial hormone sensitive lipase (HSL) superfamily, but with the conserved sequence motifs of a bacterial serine hydrolase. FTT0941c showed broad hydrolase activity against diverse libraries of ester substrates, including significant hydrolytic activity across alkyl ester substrates from 2 to 8 carbons in length. Among a diverse library of fluorogenic substrates, FTT0941c preferred α-cyclohexyl ester substrates, matching with the substrate specificity of structural homologues and the broad open architecture of its modeled binding pocket. By substitutional analysis, FTT0941c was confirmed to have a classic catalytic triad of Ser115, His278, and Asp248 and to remain thermally stable even after substitution. Its overall substrate specificity profile, divergent phylogenetic homology, and preliminary pathway analysis suggested potential biological functions for FTT0941c in diverse metabolic degradation pathways in F. tularensis