48,156 research outputs found

    Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues

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    We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique. Tissues of three human subjects, obtained at autopsy, were analyzed. BNP transcripts could be detected in the central nervous system, lung, thyroid, adrenal, kidney, spleen, small intestine, ovary, uterus, and striated muscle. ANP transcripts could also be demonstrated in various human extracardiac tissues including several endocrine organs. In all peripheral tissues, the level of both natriuretic peptide transcripts was approximately 1-2 orders of magnitude lower than in cardiac ventricular tissues. This distribution is in marked contrast to the much lower level of ANP and BNP transcripts present in extracardiac rat tissues (generally less than 1/1000 of ventricles). These data suggest differential expression of the two natriuretic peptide genes in cardiac and extracardiac tissues in man. Furthermore, the presence of local synthesis of ANP and BNP in various peripheral organs suggests paracrine and/or autocrine function of these natriuretic peptides

    Approximate expression for the dynamic structure factor in the Lieb-Liniger model

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    Recently, Imambekov and Glazman [Phys. Rev. Lett. 100, 206805 (2008)] showed that the dynamic structure factor (DSF) of the 1D Bose gas demonstrates power-law behaviour along the limiting dispersion curve of the collective modes and calculated the corresponding exponents exactly. Combining these recent results with a previously obtained strong-coupling expansion we present an interpolation formula for the DSF of the 1D Bose gas. The obtained expression is further consistent with exact low energy exponents from Luttinger liquid theory and shows nice agreement with recent numerical results.Comment: 4 pages, 3 figure

    Non-Volatile Magnonic Logic Circuits Engineering

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    We propose a concept of magnetic logic circuits engineering, which takes an advantage of magnetization as a computational state variable and exploits spin waves for information transmission. The circuits consist of magneto-electric cells connected via spin wave buses. We present the result of numerical modeling showing the magneto-electric cell switching as a function of the amplitude as well as the phase of the spin wave. The phase-dependent switching makes it possible to engineer logic gates by exploiting spin wave buses as passive logic elements providing a certain phase-shift to the propagating spin waves. We present a library of logic gates consisting of magneto-electric cells and spin wave buses providing 0 or p phase shifts. The utilization of phases in addition to amplitudes is a powerful tool which let us construct logic circuits with a fewer number of elements than required for CMOS technology. As an example, we present the design of the magnonic Full Adder Circuit comprising only 5 magneto-electric cells. The proposed concept may provide a route to more functional wave-based logic circuitry with capabilities far beyond the limits of the traditional transistor-based approach

    Sterile neutrinos, dark matter, and the pulsar velocities in models with a Higgs singlet

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    We identify the range of parameters for which the sterile neutrinos can simultaneously explain the cosmological dark matter and the observed velocities of pulsars. To satisfy all cosmological bounds, the relic sterile neutrinos must be produced sufficiently cold. This is possible in a class of models with a gauge-singlet Higgs boson coupled to the neutrinos. Sterile dark matter can be detected by the x-ray telescopes. The presence of the singlet in the Higgs sector can be tested at the Large Hadron Collider.Comment: 4 pages, one figur

    Magnetoconductivity in the presence of Bychkov-Rashba spin-orbit interaction

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    A closed-form analytic formula for the magnetoconductivity in the diffusive regime is derived in the presence of Bychkov-Rashba spin-orbit interaction in two dimensions. It is shown that at low fields B << B_{so}, where B_{so} is the characteristic field associated with spin precession, D'yakonov-Perel' mechanism leads to spin relaxation, while for B >> B_{so} spin relaxation is suppressed and the resulting spin precession contributes a Berry phase-like spin phase to the magnetoconductivity. The relative simplicity of the formula greatly facilitates data fitting, allowing for the strength of the spin-orbit coupling to be easily extracted

    Strong eigenfunction correlations near the Anderson localization transition

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    We study overlap of two different eigenfunctions as compared with self-overlap in the framework of an infinite-dimensional version of the disordered tight-binding model. Despite a very sparse structure of the eigenstates in the vicinity of Anderson transition their mutual overlap is still found to be of the same order as self-overlap as long as energy separation is smaller than a critical value. The latter fact explains robustness of the Wigner-Dyson level statistics everywhere in the phase of extended states. The same picture is expected to hold for usual d-dimensional conductors, ensuring the sβs^{\beta} form of the level repulsion at critical point.Comment: 4 pages, RevTe
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