Pudendusneuralgie: Anatomisch-chirurgische Aspekte

Zusammenfassung: Anatomie:: Das Perineum wird hauptsächlich von den Nervi pudendi versorgt. Der Nervus pudendus, ein tiefliegender Dammnerv, durchläuft mehrere Zonen, in denen Kompressionen auftreten können: zwischen dem Ligamentum supraspinatum und dem Ligamentum sacrococcygeum, zwischen dem Ligamentum sacrotuberale und dem Ligamentum sacrospinale, im Alcock-Kanal sowie im Bereich des Musculus obturatorius internus. Eine derartige Kompression kann zu einem Schmerzsyndrom im Dammbereich führen. Symptome:: Klinisch äußert sich die Kompression des Nervus pudendus durch neurologische Symptome einer Nervenkompression. Derartige Kompressionen können zu schwer diagnostizierbaren Schmerzzuständen führen. Brennende Schmerzen im Dammbereich, die eindeutig dem Versorgungsgebiet des Nervus pudendus zugeordnet werden können, im Sitzen verstärkt und einseitig auftreten, müssen an eine Kompression des Nervus pudendus denken lassen. Diagnose:: Die Diagnose stützt sich auf Anamnese und Klinik. Elektrophysiologische und bildgebende Untersuchungen dienen dem Ausschluss anderer Pathologien. Die diagnostische Infiltration des Canalis pudendalis kann in 30-40% der Fälle therapeutisch sein. Ein chirurgischer Eingriff zur Dekompression ist in 65-70% der Fälle erfolgreich. Da die Besserung oft nicht sofort eintritt, müssen die Patienten über diese Tatsache präoperativ informiert werden. Eine multidisziplinäre Betreuung ist unerlässlic

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

Many women undergo cesarean delivery without problems, however some experience significant pain after cesarean section. Pain is associated with negative short-term and long-term effects on the mother. Prior to women undergoing surgery, can we predict who is at risk for developing significant postoperative pain and potentially prevent or minimize its negative consequences? These are the fundamental questions that a team from the University of Washington, Stanford University, the Catholic University in Brussels, Belgium, Santa Joana Women's Hospital in São Paulo, Brazil, and Rambam Medical Center in Israel is currently evaluating in an international research collaboration. The ultimate goal of this project is to provide optimal pain relief during and after cesarean section by offering individualized anesthetic care to women who appear to be more 'susceptible' to pain after surgery

Voluntary informed consent in research and clinical care : an update

Informed consent is important: in research, it allows subjects to make an informed and voluntary choice to participate--or refuse to participate--in a project where they will be asked to take risks for the benefit of others. In both research and clinical care, informed consent represents a permission to intervene on a person's private sphere. The elements of informed consent are usually described as disclosure, understanding, decision-making capacity, and voluntariness. Each poses distinct difficulties, and can be amenable to improvements. However, research on the quality of informed consent and on strategies intended to improve it have only become the object of research relatively recently. In this article, we describe some results of this research, and outline how they can be relevant to informed consent in research and clinical care. Although much of the data suffers from limitations, it does suggest that disclosure has improved, but is still uneven, comprehension is often poor, for both patients and research subjects. Moreover, trust is a motivating factor for research participation, and thus we run risks if we allow false expectations and prove ourselves unworthy of this trust. Although improving consent forms does not have a clear effect on understanding, improving the consent process may help. Finally, better information may decrease anxiety and seems to have at most a small negative effect on research recruitment

Acute differential modulation of synaptic transmission and cell survival during exposure to pulsed and continuous radiofrequency energy

Pulsed radiofrequency, in which short bursts of radiofrequency energy are applied to nervous tissue, has been recently described as an alternative technique devoid of nerve injury, a subsequent side effect of thermal lesions created by continuous radiofrequency lesioning. Yet the mechanism of this effect remains unclear. In this study we compared the acute effects of pulsed versus continuous radiofrequency energy on impulse propagation and synaptic transmission in hippocampal slice cultures and on cell survival in cortical cultures. A differential effect was observed on both systems, with pulsed radiofrequency producing a transient and continuous radiofrequency a lasting inhibition of evoked synaptic activity. In addition, although both continuous radiofrequency and pulsed radiofrequency treatments induced a distance-dependent tissue destruction under the stimulating needle, the effect was more pronounced in the continuous radiofrequency group. These findings suggest that the acute effects of pulsed radiofrequency are more reversible and less destructive in nature than the classic continuous radiofrequency mode, even in normothermal conditions. This model might help elucidate the importance of various parameters for the clinical application of radiofrequency lesioning and might open new horizons for the role of pulsed radiofrequency lesioning in cases of neuropathic pain

Ethical decision-making : do anesthesiologists, surgeons, nurse anesthetists, and surgical nurses reason similarly?

Background. Principle-based ethical theory is currently available to guide health care professionals in clinical decision-making when they face ethical dilemmas. These principles include respect for autonomy (RA), nonmaleficence (NM), beneficence (B), and distributive justice. It is, however, unknown which principles, if any, guide physicians and nurses in this decision-making. The goal of our study was to explore how anesthesiologists, surgeons, nurses, and nurse anesthetists reason in the face of a moral dilemma. Methods. By an anonymous survey we asked: Would you give a blood transfusion to a young, ASA I, Jehovah's Witness who clearly refused transfusion, in a case of a life-threatening bleeding? What ethical principle did you apply in your decision? We presented this question before and after a 1-hour ethical tutorial about these principles. Results. Twenty-nine anesthesiologists, 41 surgeons, 21 surgical nurses, and 33 nurse anesthetists participated in our survey. We found that 59%, 30%, 29%, and 36% of anesthesiologists, surgeons, surgical nurses, and nurse anesthetists, respectively, would give a blood transfusion despite the patient's demand. Nurses used B, surgeons NM, and anesthesiologists B and NM to justify trans-fusion. However, two among 11 anesthesiologists and five among 12 surgeons did not explain their choice. Those who tend to withhold blood transfusion overwhelmingly used RA as the principle behind this decision. Nine participants changed their view before and after the tutorial. There was no correlation between gender, age, and professional experience with the choice of principle. The average interest score for the tutorial was 74/100 for all participants after this ethical course. Conclusions. Anesthesiologists tend to transfuse Jehovah's Witness patients more than did the others. Together with surgeons, they explicitly justify their decision-making less frequently when compared with nurses and nurse anesthetists. Further education in ethical theory is appreciated and needed