90 research outputs found

    Pandemic response strategies and threshold phenomena

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    This paper critically evaluates the Suppression Threshold Strategy (STS) for controlling Covid-19 (C-19). STS asserts a “fundamental distinction” between suppression and mitigation strategies, reflected in very different outcomes in eventual mortality depending on whether reproductive number R is caused to fall below 1. We show that there is no real distinction based on any value of R which falls in any case from early on in an epidemic wave. We show that actual mortality outcomes lay on a continuum, correlating with suppression levels, but not exhibiting any step changes or threshold effects. We argue that an excessive focus on achieving suppression at all costs, driven by the erroneous notion that suppression is a threshold, led to a lack of information on how to trade off the effects of different specific interventions. This led many countries to continue with inappropriate intervention-packages even after it became clear that their initial goal was not going to be attained. Future pandemic planning must support the design of “Plan B", which may be quite different from “Plan A"

    Philosophy of Medicine and Covid-19: Must Do Better

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    The Covid-19 pandemic was a world event on our intellectual doorstep. What were our duties to respond, and how well did we respond? We published papers, but we did not engage extensively or influentially in public debate. Perhaps we felt we were not experts. Yet in a health crisis, philosophers of medicine can offer not only “conceptual clarification,” but also domain-specific knowledge concerning structural properties of relevant sciences and their social-political uses. I set out three conditions for the kind of contribution I felt was lacking: public, critical, and timely. And I call for us to do more of it

    Talking responsibly about medicine in the Fourth Industrial Revolution

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    Abstract: Please refer to full text to view abstrac

    Causes of causes

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    Editorial: Philosophical Perspectives on Covid-19

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    Editoria

    QMA-hardness of Consistency of Local Density Matrices with Applications to Quantum Zero-Knowledge

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    We provide several advances to the understanding of the class of Quantum Merlin-Arthur proof systems (QMA), the quantum analogue of NP. Our central contribution is proving a longstanding conjecture that the Consistency of Local Density Matrices (CLDM) problem is QMA-hard under Karp reductions. The input of CLDM consists of local reduced density matrices on sets of at most k qubits, and the problem asks if there is an n-qubit global quantum state that is consistent with all of the k-qubit local density matrices. The containment of this problem in QMA and the QMA-hardness under Turing reductions were proved by Liu [APPROX-RANDOM 2006]. Liu also conjectured that CLDM is QMA-hard under Karp reductions, which is desirable for applications, and we finally prove this conjecture. We establish this result using the techniques of simulatable codes of Grilo, Slofstra, and Yuen [FOCS 2019], simplifying their proofs and tailoring them to the context of QMA. In order to develop applications of CLDM, we propose a framework that we call locally simulatable proofs for QMA: this provides QMA proofs that can be efficiently verified by probing only k qubits and, furthermore, the reduced density matrix of any k-qubit subsystem of an accepting witness can be computed in polynomial time, independently of the witness. Within this framework, we show advances in quantum zero-knowledge. We show the first commit-and-open computational zero-knowledge proof system for all of QMA, as a quantum analogue of a "sigma" protocol. We then define a Proof of Quantum Knowledge, which guarantees that a prover is effectively in possession of a quantum witness in an interactive proof, and show that our zero-knowledge proof system satisfies this definition. Finally, we show that our proof system can be used to establish that QMA has a quantum non-interactive zero-knowledge proof system in the secret parameter setting.Comment: Title changed to highlight the QMA-hardness proof of CLDM. Improvement on the presentation of the paper (including self-contained proofs of results needed from Grilo, Slofstra, and Yuen'19). The extended abstract of this paper appears in the proceedings of FOCS'202

    A Beginner’s Guide to Crossing the Road: Towards an Epistemology of Successful Action in Complex Systems

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    Crossing the road within the traffic system is an example of an action human agents perform successfully day-to-day in complex systems. How do they perform such successful actions given that the behaviour of complex systems is often difficult to predict? The contemporary literature contains two contrasting approaches to the epistemology of complex systems: an analytic and a post-modern approach. We argue that neither approach adequately accounts for how successful action is possible in complex systems. Agents regularly perform successful actions without obeying (explicit or implicit) algorithmic rules (as the analytic approach suggests) and without an existential leap to action (as the post-modern approach suggests). We offer an alternative: A common-sense pragmatist epistemology, one that focuses on the kind of actions making up most agents’ successful moment-to-moment actions in complex systems. Successful actions obtain when agents apply ceteris paribus rules-of-thumb during predictive and decisional practices while achieving some desired goal
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