Impact of the COVID-19 pandemic on the academic life of higher education students: A rural South African perspective from a global study

Globally, the COVID-19 pandemic has become a greatest challenge in all sectors of life in the 21st Century. Due to worldwide lockdown and social distancing regulations, higher education institutions who offer face-to face classes had to go online to provide educational services to their students, which had major impacts on student lives. To study the immediate effects of it, a global study on the life of higher education students, initiated by University of Ljubljana (with international partners) was conducted as a voluntary and anonymous online survey across the world started on 5 May 2020. The survey targeted higher education students ‒ on what student life looks like during the COVID-19 pandemic, in different parts of the world. This article reports on part of that global study, reporting on the teaching and learning aspect of a sample of 274 undergraduate students from a South African rural higher education institution (HEI) who participated in the study. Thus, this article highlights the immediate impacts of the pandemic during 5 May – 15 June 2020 of the rural HEI. The study is important as the student perspective can have an impact on post- COVID academic policies of HEIs with similar contexts. &nbsp

Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for healthcare policy and decision making

Objective: Network meta-analyses have extensively been used to compare the effectiveness of multiple interventions for healthcare policy and decision-making. However, methods for evaluating the performance of multiple diagnostic tests are less established. In a decision-making context, we are often interested in comparing and ranking the performance of multiple diagnostic tests, at varying levels of test thresholds, in one simultaneous analysis. Study design and setting: Motivated by an example of cognitive impairment diagnosis following stroke, we synthesized data from 13 studies assessing the efficiency of two diagnostic tests: Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), at two test thresholds: MMSE <25/30 and <27/30, and MoCA <22/30 and <26/30. Using Markov Chain Monte Carlo (MCMC) methods, we fitted a bivariate network meta-analysis model incorporating constraints on increasing test threshold, and accounting for the correlations between multiple test accuracy measures from the same study. Results: We developed and successfully fitted a model comparing multiple tests/threshold combinations while imposing threshold constraints. Using this model, we found that MoCA at threshold <26/30 appeared to have the best true positive rate, whilst MMSE at threshold <25/30 appeared to have the best true negative rate. Conclusion: The combined analysis of multiple tests at multiple thresholds allowed for more rigorous comparisons between competing diagnostics tests for decision making

The Impact of Galactic Disc Environment on Star-Forming Clouds

We explore the effect of different galactic disc environments on the properties of star-forming clouds through variations in the background potential in a set of isolated galaxy simulations. Rising, falling and flat rotation curves expected in halo dominated, disc dominated and Milky Way-like galaxies were considered, with and without an additional two-arm spiral potential. The evolution of each disc displayed notable variations that are attributed to different regimes of stability, determined by shear and gravitational collapse. The properties of a typical cloud were largely unaffected by the changes in rotation curve, but the production of small and large cloud associations was strongly dependent on this environment. This suggests that while differing rotation curves can influence where clouds are initially formed, the average bulk properties are effectively independent of the global environment. The addition of a spiral perturbation made the greatest difference to cloud properties, successfully sweeping the gas into larger, seemingly unbound, extended structures and creating large arm-interarm contrasts.Comment: Accepted to MNRAS on 3rd December, 201

CP-violating theta parameter in the domain model of the QCD vacuum

A non-zero CP-violating $\theta$ parameter is treated in the domain model which assumes a cluster-like vacuum structure whose units are characterised in particular by a topological charge which is not necessarily an integer number. In the present paper we restrict consideration to rational values of the charge. The model has previously been shown to manifest confinement, spontaneous chiral symmetry breaking and the absence of an axial U(1) Goldstone boson. We find that the specific structure of the minima of the free energy density of the domain ensemble forces a $2\pi$-periodicity of observables in $\theta$ for any number of light quarks, that vacuum doubling occurs at $\theta=\pi$ for any $N_f>1$ and any value of topological charge $q$. These features are in agreement with expectations based on anomalous Ward identities and large $N_c$ effective theories. We find also additional values of $\theta$ depending on $q$ for which vacuum doubling occurs.Comment: 10 pages, 6 figures. Final version with modification of Eq.(2), additional references, minor typographical correction

Palladium-bismuth intermetallic and surface-poisoned catalysts for the semi-hydrogenation of 2-methyl-3-butyn-2-ol

The effects of poisoning of Pd catalysts with Bi and annealing in a polyol (ethylene glycol) were studied on the semi-hydrogenation of 2-methyl-3-butyn-2-ol (MBY). An increase in the Pd:Bi ratio from 7 to 1 in the Bi-poisoned catalysts decreased the hydrogenation activity due to blocking of active sites, but increased maximum alkene yield from 91.5% for the Pd catalyst to 94–96% for all Bi-poisoned Pd catalysts, by decreasing the adsorption energy of alkene molecules and suppressing the formation of β-hydride phase. Annealing of the catalysts induced the formation of intermetallic phases and decreased its activity due to sintering of the catalytic particles and low activity of intermetallic compounds. Langmuir–Hinshelwood kinetic modelling of the experimental data showed that poisoning of Pd with Bi changed the relative adsorption constants of organic species suggesting ligand effects at high Bi content

Quality education for sustainable development: Are we on the right track? Evidence from the TIMSS 2015 study in South Africa

Obtaining quality education provides the foundation for improving people’s lives and contributes to sustainable development. The world has come a long way in achieving the goal of equality in primary education for girls and boys, but few countries have achieved that target at all levels of education, as reported by UNICEF (2016). The Human Sciences Research Council of South Africa, in 2016, warned that social ills such as South Africa’s high levels of poverty, inequality and unemployment have an effect on the quality of education offered, taking into account different levels of education at various schools. South Africa now participates in many national and international benchmarking studies to assess its progress in the quality of schooling and in specific areas of the curriculum against international standards. The Trends in International Mathematics and Science Study (TIMSS) is one of the studies in which South Africa has participated since 1995. Subsequent to1995, the country has made considerable progress in mathematics and science achievement – key subjects for much-needed national development. Approximately 12 500 grade 9 learners participated in the 2015 TIMSS from South Africa. The purpose of this paper is therefore to investigate the contextual factors that exist and to critically assess the progress made by senior phase mathematics learners in TIMSS 2015. This is to make recommendations in order to accelerate this progress thereby positively contributing to learners’ performance in the Eastern Cape and, in the long term, to the achievement of Sustainable Development Goals (SDGs) as laid out in the National Development Plan of 2030 for South Africa

Pulsed Adiabatic Photoassociation via Scattering Resonances

We develop the theory for the Adiabatic Raman Photoassociation (ARPA) of ultracold atoms to form ultracold molecules in the presence of scattering resonances. Based on a computational method in which we replace the continuum with a discrete set of "effective modes", we show that the existence of resonances greatly aids in the formation of deeply bound molecular states. We illustrate our general theory by computationally studying the formation of $^{85}$Rb$_2$ molecules from pairs of colliding ultracold $^{85}$Rb atoms. The single-event transfer yield is shown to have a near-unity value for wide resonances, while the ensemble-averaged transfer yield is shown to be higher for narrow resonances. The ARPA yields are compared with that of (the experimentally measured) "Feshbach molecule" magneto-association. Our findings suggest that an experimental investigation of ARPA at sub-$\mu$K temperatures is warranted.Comment: 20 pages, 11 figure

Stress Fractures of the Elbow in the Throwing Athlete: A Systematic Review.

Background: Stress fractures of the elbow are rare in throwing athletes and present a challenge from both a management and rehabilitation perspective. Although the incidence of stress fractures of the elbow is increasing, there is a lack of data in the literature focused on throwers. Purpose: To evaluate studies regarding the management and outcomes of stress fractures of the elbow in throwing athletes. Study Design: Systematic review; Level of evidence, 4. Methods: A systematic review was conducted by searching the Scopus, PubMed, and Cochrane Library electronic databases to identify studies reporting on the management and outcomes of stress fractures in overhead-throwing athletes. Management data included nonoperative and operative modalities, and outcome data included return to play, encompassing the timing and level of activity. Studies were excluded if the stress fracture of the elbow was not a result of a sport injury attributed to throwing or if the study failed to report whether an athlete returned to play. Results: Fourteen studies met the inclusion criteria and were included in this analysis. There were 52 patients in total (50 male, 2 female) with a mean age of 19.7 years (range, 13-29.1 years). The olecranon was the most common location of the stress fracture (51 patients; 98.1%), followed by the distal humerus (1 patient; 1.9%). The majority of patients (n = 40; 76.9%) were treated operatively. Of the 40 patients who were treated surgically, 14 (35.0%) underwent a period of conservative treatment preoperatively that ultimately failed because of persistent nonunion or continued elbow pain. A total of 50 patients (96.2%) returned to sport either at or above their preinjury level. Of the 2 patients (3.8%) who did not return to sport, 1 did not return because of continued elbow pain postoperatively, and the other was lost to follow-up. Complications occurred in 9 patients (17.3%), all of whom were treated surgically. Conclusion: On the basis of this systematic review, the majority of elbow stress fractures were treated operatively and approximately one-third after a period of failed nonoperative management. The return-to-sport rate was high. Further, higher level studies are needed to optimize management and return-to-sport rates in this population

Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos.

Arteries and veins are formed independently by different types of endothelial cells (ECs). In vascular remodeling, arteries and veins become connected and some arteries become veins. It is unclear how ECs in transforming vessels change their type and how fates of individual vessels are determined. In embryonic zebrafish trunk, vascular remodeling transforms arterial intersegmental vessels (ISVs) into a functional network of arteries and veins. Here we find that, once an ISV is connected to venous circulation, venous blood flow promotes upstream migration of ECs that results in displacement of arterial ECs by venous ECs, completing the transformation of this ISV into a vein without trans-differentiation of ECs. Arterial blood flow initiated in two neighboring ISVs prevents their transformation into veins by activating Notch signaling in ECs. Together, different responses of ECs to arterial and venous blood flow lead to formation of a balanced network with equal numbers of arteries and veins