Pay Dispersion and Work Performance

The effect of intra-firm pay dispersion on work performance is controversial and the empirical evidence is mixed. High pay dispersion may act as an extra incentive for employees' effort or it may reduce motivation and team cohesiveness. These effects can also coexist and the prevalence of one effect over the other may depend on the use of different definitions of what constitutes a "team." For this paper we collected a unique dataset from the men's major soccer league in Italy. For each match we computed the exact pay dispersion of each work team and estimated its effect on team performance. Our results show that when the work team is considered to consist of only the players who contribute to the result, high pay dispersion has a detrimental impact on team performance. Several robustness checks confirm this result. In addition, we show that enlarging the definition of work team causes this effect to disappear or even become positive. Finally, we find that the detrimental effect of pay dispersion is due to worst individual performance, rather than a reduction of team cooperation.Team productivity, Incentives, Pay dispersion.

Luck or Cheating? A Field Experiment on Honesty with Children

We ran an experiment with children to study the development of honesty with age. We asked each child to toss a fair coin in private and to record the outcome (white or black) in a paper sheet. We rewarded only those who reported white. We found a fraction of reported whites signifi…cantly larger than 50%, uniformly across age groups. This suggests that some children cheat when cheating is profi…table and they are not observed. In a second treatment we told children not to cheat. This reminder reduced the probability of reporting white by 18% on average, and signifi…cantly more in girls.honesty; children; fi…eld experiment

Do not Trash the Incentive! Monetary incentives and waste sorting

This paper examines whether monetary incentives are an effective tool for increasing domestic waste sorting. We exploit the exogenous variation in the waste management policies experienced during the years 1999-2008 by the 95 municipalities in the district of Treviso (Italy). We estimate with a panel analysis that pay-as-you-throw (PAYT) incentive schemes increase by 12.3% the sorted-total waste ratio. This increase reflects a change in the behavior of households, who keep unaltered the production of total waste but sort it to a larger extent. Our data show that household behavior is also influenced by the policies of adjacent municipalities.Incentives, environment, waste management, PAYT

Temptation at work

To encourage worker productivity offices prohibit Internet use. Consequently, many employees delay Internet activity to the end of the workday. Recent work in social psychology, however, suggests that using willpower to delay gratification can negatively impact performance. We report data from an experiment where subjects in a Willpower Treatment are asked to resist the temptation to join others in watching a humorous video for 10 minutes. In relation to a baseline treatment that does not require willpower, we show that resisting this temptation detrimentally impacts economic productivity on a subsequent task.temptation, willpower, lab experiment.

Mapping of land use changes and carbon sequestration along a segment of the city walls system of Padua

openI servizi ecosistemici sono i benefici forniti dall’ambiente all’uomo e le reti ecologiche urbane riescono a erogare diversi di questi servizi. Un importante servizio ecosistemico è lo stoccaggio e il sequestro di carbonio che rappresenta la quantità di carbonio assorbita dall’azione dei sistemi vegetali. L’obiettivo generale della tesi mira a valutare e geovisualizzare la qualità del servizio ecosistemico di stoccaggio e sequestro di carbonio in un tratto della cinta muraria di Padova tra il 1955 e il 2018. Per raggiungere questo obiettivo si è proceduto a mappare l’uso del suolo dell’area di studio negli anni 1955, 1981 e 2018, mediante la fotointerpretazione di immagini aeree storiche e recenti utilizzando il software QGIS. Successivamente le mappe ottenute sono state elaborate con il software InVEST, calcolando il sequestro e lo stoccaggio di carbonio con il modello “Carbon Storage and Sequestration”. I risultati ottenuti mostrano che, dal 1955 al 2018, le aree impermeabili sono aumentate a discapito del verde prativo. I risultati hanno mostrato inoltre che le aree di verde arboreo, in questo arco di tempo, sono aumentate. L’effetto complessivo di questo cambiamento di uso del suolo è stato l’aumento di 182,37 t di carbonio stoccato e sequestrato. Dai risultati è possibile concludere che la realizzazione di aree verdi alberate all’interno delle città è stata di notevole importanza per mantenere il bilancio tra carbonio sequestrato e carbonio liberato in favore del primo, e che un incremento di queste aree nel futuro, continuando le opere di messa a dimora di nuovi alberi, potrà portare a benefici per la popolazione della città e per l’ambiente

Reasoning and querying bounds on differences with layered preferences

Artificial intelligence largely relies on bounds on differences (BoDs) to model binary constraints regarding different dimensions, such as time, space, costs, and calories. Recently, some approaches have extended the BoDs framework in a fuzzy, \u201cnoncrisp\u201d direction, considering probabilities or preferences. While previous approaches have mainly aimed at providing an optimal solution to the set of constraints, we propose an innovative class of approaches in which constraint propagation algorithms aim at identifying the \u201cspace of solutions\u201d (i.e., the minimal network) with their preferences, and query answering mechanisms are provided to explore the space of solutions as required, for example, in decision support tasks. Aiming at generality, we propose a class of approaches parametrized over user\u2010defined scales of qualitative preferences (e.g., Low, Medium, High, and Very High), utilizing the resume and extension operations to combine preferences, and considering different formalisms to associate preferences with BoDs. We consider both \u201cgeneral\u201d preferences and a form of layered preferences that we call \u201cpyramid\u201d preferences. The properties of the class of approaches are also analyzed. In particular, we show that, when the resume and extension operations are defined such that they constitute a closed semiring, a more efficient constraint propagation algorithm can be used. Finally, we provide a preliminary implementation of the constraint propagation algorithms

Effect of Binding Modules Fused to Cutinase on the Enzymatic Synthesis of Polyesters

open9In relation to the development of environmentally-friendly processing technologies for the continuously growing market of plastics, enzymes play an important role as green and sustainable biocatalysts. The present study reports the use of heterogeneous immobilized biocatalysts in solvent-free systems for the synthesis of aliphatic oligoesters with Mws and monomer conversions up to 1500 Da and 74%, respectively. To improve the accessibility of hydrophilic and hydrophobic substrates to the surface of the biocatalyst and improve the reaction kinetic and the chain elongation, two different binding modules were fused on the surface of cutinase 1 from Thermobifida cellulosilytica. The fusion enzymes were successfully immobilized (>99% of bound protein) via covalent bonding onto epoxy-activated beads. To the best of our knowledge, this is the first example where fused enzymes are used to catalyze transesterification reactions for polymer synthesis purposes.openFerrario, Valerio; Todea, Anamaria; Wolansky, Lisa; Piovesan, Nicola; Guarneri, Alice; Ribitsch, Doris; Guebitz, Georg M.; Gardossi, Lucia; Pellis, AlessandroFerrario, Valerio; Todea, Anamaria; Wolansky, Lisa; Piovesan, Nicola; Guarneri, Alice; Ribitsch, Doris; Guebitz, Georg M.; Gardossi, Lucia; Pellis, Alessandr

Valproic Acid, a Histone Deacetylase Inhibitor, in Combination with Paclitaxel for Anaplastic Thyroid Cancer: Results of a Multicenter Randomized Controlled Phase II/III Trial

Anaplastic thyroid cancer (ATC) has a median survival less than 5 months and, to date, no effective therapy exists. Taxanes have recently been stated as the main drug treatment for ATC, and the histone deacetylase inhibitor valproic acid efficiently potentiates the effects of paclitaxel in vitro. Based on these data, this trial assessed the efficacy and safety of the combination of paclitaxel and valproic acid for the treatment of ATC. This was a randomized, controlled phase II/III trial, performed on 25 ATC patients across 5 centers in northwest Italy. The experimental arm received the combination of paclitaxel (80 mg/m2/weekly) and valproic acid (1,000 mg/day); the control arm received paclitaxel alone. Overall survival and disease progression, evaluated in terms of progression-free survival, were the primary outcomes. The secondary outcome was the pharmacokinetics of paclitaxel. The coadministration of valproic acid did not influence the pharmacokinetics of paclitaxel. Neither median survival nor median time to progression was statistically different in the two arms. Median survival of operated-on patients was significantly better than that of patients who were not operated on. The present trial demonstrates that the addition of valproic acid to paclitaxel has no effect on overall survival and disease progression of ATC patients. This trial is registered with EudraCT 2008-005221-11

Systematic reanalysis of partial trisomy 21 cases with or without Down syndrome suggests a small region on 21q22.13 as critical to the phenotype

A "Down Syndrome critical region" (DSCR) sufficient to induce the most constant phenotypes of Down syndrome (DS) had been identified by studying partial (segmental) trisomy 21 (PT21) as an interval of 0.6-8.3 Mb within human chromosome 21 (Hsa21), although its existence was later questioned. We propose an innovative, systematic reanalysis of all described PT21 cases (from 1973 to 2015). In particular, we built an integrated, comparative map from 125 cases with or without DS fulfilling stringent cytogenetic and clinical criteria. The map allowed to define or exclude as candidates for DS fine Hsa21 sequence intervals, also integrating duplication copy number variants (CNVs) data. A highly restricted DSCR (HR-DSCR) of only 34 kb on distal 21q22.13 has been identified as the minimal region whose duplication is shared by all DS subjects and is absent in all non-DS subjects. Also being spared by any duplication CNV in healthy subjects, HR-DSCR is proposed as a candidate for the typical DS features, the intellectual disability and some facial phenotypes. HR-DSCR contains no known gene and has relevant homology only to the chimpanzee genome. Searching for HR-DSCR functional loci might become a priority for understanding the fundamental genotype-phenotype relationships in DS

Prognostic Value of Whole-Body PET Volumetric Parameters Extracted from 68Ga-DOTATOC PET/CT in Well-Differentiated Neuroendocrine Tumors

Our objective was to evaluate the prognostic value of somatostatin receptor tumor burden on Ga-68-DOTATOC PET/CT in patients with well-differentiated (WD) neuroendocrine tumors (NETs). Methods: We retrospectively analyzed the 68Ga-DOTATOC PET/CT scans of 84 patients with histologically confirmed WD NETs (51 grade 1, 30 grade 2, and 3 grade 3). For each PET/CT scan, all Ga-68-DOTATO-Cavid lesions were independently segmented by 2 operators using a customized threshold based on the healthy liver SUVmax (LIFEx, version 5.1). Somatostatin receptor-expressing tumor volume (SRETV) and total lesion somatostatin receptor expression (TLSRE = SRETV X SUVmean) were extracted for each lesion, and then whole-body SRETV and TLSRE (SRETVwb and TLSREwb, respectively) were defined as the sum of SRETV and TLSRE, respectively, for all segmented lesions in each patient. Time to progression (TTP) was defined as the combination of disease-free survival in patients undergoing curative surgery (n = 10) and progression-free survival for patients with unresectable or metastatic disease (n = 74). TTP and overall survival were calculated by Kaplan-Meier analysis, log-rank testing, and the Cox proportional-hazards regression model. Results: After a median follow-up of 15.5 mo, disease progression was confirmed in 35 patients (41.7%) and 14 patients died. A higher SRETVwb (>39.1 cm(3)) and TLSREwb (>306.8 g) correlated significantly with a shortermedian TTP (12 mo vs. not reached; P < 0.001). In multivariate analysis, SRETVwb (P = 0.005) was the only independent predictor of TTP regardless of histopathologic grade and TNM staging. Conclusion: According to our results, SRETVwb and TLSREwb extracted from Ga-68-DOTATOC PET/CT could predict TTP or overall survival and might have important clinical utility in the management of patients with WD NETs