Synergy of multispectral and multisensors satellite observations to evaluate desert aerosol transport and impact of dust deposition on inland waters: study case of Lake Garda

The capabilities of different Earth Observation multispectral satellites are employed for detecting and tracking of desert dust coming from North Africa toward the Northern Italy area and for evaluating the impact of Saharan dust deposition in inland waters, such as those of Lake Garda. Absorbing and scattering spectral optical properties of desert aerosol in the atmospheric windows in the ultraviolet, visible-near-infrared, and infrared spectral ranges are exploited in the dust retrieval performed by OMI/Aura, MODIS/Terra-Aqua, and SEVIRI/MSG satellite sensors. Therefore, the direct link between dust deposition and increase in phytoplankton abundance has been assessed retrieving MERIS-based chlorophyll-a (chl-a) concentration for the desert dust events. Estimates of the increased chl-a in the lake have been derived with values in concentration from 30% to 170%. AERONET sun-photometer measurements, gravimetric particulate matter samplings

Improved SIFTER v2 algorithm for long-term GOME-2A satellite retrievals of fluorescence with a correction for instrument degradation

Solar-induced fluorescence (SIF) data from satellites are increasingly used as a proxy for photosynthetic activity by vegetation and as a constraint on gross primary production. Here we report on improvements in the algorithm to retrieve mid-morning (09:30 LT) SIF estimates on the global scale from the GOME-2 sensor on the MetOp-A satellite (GOME-2A) for the period 2007-2019. Our new SIFTER (Sun-Induced Fluorescence of Terrestrial Ecosystems Retrieval) v2 algorithm improves over a previous version by using a narrower spectral window that avoids strong oxygen absorption and being less sensitive to water vapour absorption, by constructing stable reference spectra from a 6-year period (2007-2012) of atmospheric spectra over the Sahara and by applying a latitude-dependent zero-level adjustment that accounts for biases in the data product. We generated stable, good-quality SIF retrievals between January 2007 and June 2013, when GOME-2A degradation in the near infrared was still limited. After the narrowing of the GOME-2A swath in July 2013, we characterised the throughput degradation of the level-1 data in order to derive reflectance corrections and apply these for the SIF retrievals between July 2013 and December 2018. SIFTER v2 data compare well with the independent NASA v2.8 data product. Especially in the evergreen tropics, SIFTER v2 no longer shows the underestimates against other satellite products that were seen in SIFTER v1. The new data product includes uncertainty estimates for individual observations and is best used for mostly clear-sky scenes and when spectral residuals remain below a certain spectral autocorrelation threshold. Our results support the use of SIFTER v2 data being used as an independent constraint on photosynthetic activity on regional to global scales.</p

Multi-Sensor Retrieval of Aerosol Optical Properties for Near-Real-Time Applications Using the Metop Series of Satellites: Concept, Detailed Description, and First Validation

The Polar Multi-Sensor Aerosol product (PMAp) is based on the synergistic use of three instruments from the Metop platform, GOME-2, AVHRR, and IASI. The retrieval algorithm includes three major steps: a pre-identification of the aerosol class, a selection of the aerosol model, and a calculation of the Aerosol Optical Depth (AOD). This paper provides a detailed description of the PMAp retrieval, which combines information provided by the three instruments. The retrieved AOD is qualitatively evaluated, and a good temporal as well as spatial performance is observed, including for the transition between ocean and land. More quantitatively, the performance is evaluated by comparison to AERONET in situ measurements. Very good consistency is also observed when compared to other space-based data such as MODIS or VIIRS. The paper demonstrates the ability of this first generation of synergistic products to derive reliable AOD, opening the door for the development of synergistic products from the instruments to be embarked on the coming Metop Second Generation platform. PMAp has been operationally distributed in near-real-time since 2014 over ocean, and 2016 over land

Multi-Sensor Retrieval of Aerosol Optical Properties for Near-Real-Time Applications Using the Metop Series of Satellites: Concept, Detailed Description, and First Validation

The Polar Multi-Sensor Aerosol product (PMAp) is based on the synergistic use of three instruments from the Metop platform, GOME-2, AVHRR, and IASI. The retrieval algorithm includes three major steps: a pre-identification of the aerosol class, a selection of the aerosol model, and a calculation of the Aerosol Optical Depth (AOD). This paper provides a detailed description of the PMAp retrieval, which combines information provided by the three instruments. The retrieved AOD is qualitatively evaluated, and a good temporal as well as spatial performance is observed, including for the transition between ocean and land. More quantitatively, the performance is evaluated by comparison to AERONET in situ measurements. Very good consistency is also observed when compared to other space-based data such as MODIS or VIIRS. The paper demonstrates the ability of this first generation of synergistic products to derive reliable AOD, opening the door for the development of synergistic products from the instruments to be embarked on the coming Metop Second Generation platform. PMAp has been operationally distributed in near-real-time since 2014 over ocean, and 2016 over land

Analysis of dust aerosols in PMAp Climate Data Record

info:eu-repo/semantics/nonPublishe

Active and Total Ghrelin Concentrations in the Newborn

BACKGROUND: Ghrelin is a peptide with a potent capacity to release GH and other metabolic activities. An acyl modification is indispensable for biological activity. Acylated and desacylated forms of ghrelin are both present in the blood. No data exist about the ratio between active ghrelin and total ghrelin in the first period of life. OBJECTIVE: To investigate whether ghrelin may be involved in physiological roles during fetal life. INFANTS AND METHODS: Ghrelin, growth hormone (GH), and leptin concentrations were measured in cord plasma in 98 newborns of healthy mothers. Acyl-ghrelin and the sum of acylated and desacylated forms of ghrelin (total ghrelin) were measured using specific radioimmunoassays. RESULTS: Acylated ghrelin and total ghrelin did not correlate with birth weight, gestational age, body mass index, head circumference, birth length, leptin or GH in plasma cord blood. CONCLUSIONS: The absence of clinically significant correlations between both active and total ghrelin and GH, leptin or anthropometric data does not enable us to ascribe a precise role to ghrelin in prenatal life

Repolarization effects of multiple-cycle chemotherapy and predictors of QTc prolongation: A prospective female cohort study on >2000 ECGs

Purpose: Oncological patients are at increasing risk of QT prolongation, a risk factor for ventricular arrhythmia. We assessed impact and risk factors for corrected QT (QTc) prolongation during multiple-cycle chemotherapy. Methods: We enrolled 100 outpatients initiating chemotherapy in a university center specializing in female cancer. Clinical, drug, laboratory, and 12-lead ECG data collection at baseline and at each chemotherapy cycle was performed. Results: Enrolled patients were followed for 992 chemotherapy cycles (median 7; interquartile range 6-13); 2438 ECGs were recorded (20; 18-31) 36.8 % pre-therapy, 36.8 % following chemotherapy, and 22.5 % 7-10 days after chemotherapy. Maximum QTc (Max-QTc) was recorded after 4 chemotherapy administrations in >50 % of the entire cohort and also within every subset of patients with prolonged QTc (57 % 471-480 ms; 54 % 481-500 ms; 66 % >500 ms). No cumulative effect on QTc was shown. QTc prolongation was comparable among the various protocols. Prophylactic/supportive drugs were not associated with additional QTc prolongation. Variables independently associated with QTc prolongation >470 ms were age (OR 1.056 95 % CI 1.006-1.108, p 08= 080.028) and the baseline-first chemotherapy averaged QTc (BC-QTc) (OR 1.092 95 % CI 1.051-1.136), a novel parameter devised for this study. Only BC-QTc maintained significance for QTc >480 ms. BC-QTc >435 ms identified 100 % of patients with Max-QTc >500 ms, 96 % with Max-QTc 481-500 ms, and 66 % with Max-QTc 471-480 ms. Only 29 % of patients with Max-QTc 470 ms presented a BC-QTc >435 ms. Conclusions: Our results confirm the high prevalence of QTc prolongation after chemotherapy. Most of the patients reached Max-QTc after several cycles. BC-QTc may help in stratifying arrhythmic risk in real-world clinical practice