Scalability and power consumption of static optical core networks

Abstract — A large amount of traffic in core networks is highly aggregated and core nodes are interconnected by high-capacity links. Thus, most of the traffic demands in the core area can be accommodated by providing more or less static connections between ingress and egress nodes. In this paper, we describe and study three particular realizations of static optical core networks and compare them with the dynamic, packet switched architecture based on wavelength-division multiplexing (WDM) transmission and conventional electronic packet routers. We introduce an analytical model for estimating the average number of required switch ports for different network topologies in order to assess both scalability and power consumption of the considered network concepts. The results show that the concept of a static optically transparent core network promises high energy efficiency, and scalability to several tens of nodes. I

Scalability and power consumption of static optical core networks

Abstract — A large amount of traffic in core networks is highly aggregated and core nodes are interconnected by high-capacity links. Thus, most of the traffic demands in the core area can be accommodated by providing more or less static connections between ingress and egress nodes. In this paper, we describe and study three particular realizations of static optical core networks and compare them with the dynamic, packet switched architecture based on wavelength-division multiplexing (WDM) transmission and conventional electronic packet routers. We introduce an analytical model for estimating the average number of required switch ports for different network topologies in order to assess both scalability and power consumption of the considered network concepts. The results show that the concept of a static optically transparent core network promises high energy efficiency, and scalability to several tens of nodes. I

Dimensioning the future pan-European optical network with energy efficiency considerations

This paper studies the overall energy consumption of a pan-European optical transport network for three different time periods: today and in five and ten years from now. In each time period the pan-European network was dimensioned using traffic predictions based on realistic data generated by the optical networking roadmap developed in the framework of the European project Building the Future Optical Network in Europe-BONE. A wavelength routed wavelength division multiplexed optical network based on either transparent or opaque node architectures was examined considering exclusively either 10 Gbit/s or 40 Gbit/s per channel data rates. The results manifest that transparent optical networking technologies are expected to provide significant energy savings of the order of 35% to 55%. It was also shown that the migration towards higher data rates, i.e., from 10 Gbit/s to 40 Gbit/s, is assisting in improving the overall energy efficiency of the network

N-benzyl derivatives of long-chained 4-Amino-7-chloro-quionolines as inhibitors of pyocyanin production in Pseudomonas aeruginosa

Pseudomonas aeruginosa is a leading cause of nosocomial infections that are becoming increasingly difficult to treat due to the occurrence of antibiotic resistant strains. Since P. aeruginosa virulence is controlled through quorum sensing, small molecule treatments inhibiting quorum sensing signaling pathways provide a promising therapeutic option. Consequently, we synthesized a series of N-octaneamino-4-aminoquinoline derivatives to optimize this chemotype’s antivirulence activity against P. aeruginosa via inhibition of pyocyanin production. The most potent derivative, which possesses a benzofuran substituent, provided effective inhibition of pyocyanin production (IC50 = 12 μM), biofilm formation (BFIC50 = 50 μM), and motility. Experimentally, the compound’s activity is achieved through competitive inhibition of PqsR, and structure–activity data were rationalized using molecular docking studies.The peer-reviewed version: [http://cer.ihtm.bg.ac.rs/handle/123456789/3341