Lista patrón de los tiburones, rayas y quimeras (Chondrichthyes, Elasmobranchii, Holocephali) de México

Llista patró dels taurons, rajades i quimeres (Chondrichthyes, Elasmobranchii, Holocephali) de Mèxic Es presenta una relació de les espècies de taurons, rajades  i quimeres (condrictis) que han estat registrades a les aigües territorials de Mèxic, basada en revisions de bases de dades, literatura, examen físic dels espècimens de col·leccions científiques i registres d’exemplars recol·lectats en treballs de camp durant els darrers quatre anys i que no han estat publicats. La relació conté informació de 214 espècies de condrictis que, com a mínim, han estat registrades a les aigües marines i salobroses de Mèxic, pertanyents a 84 gèneres, 40 famílies i 14 ordres. S’hi inclouen vuit espècies de quimeres, 95 de batoïdeus i 111 de taurons. La condrictiofauna mexicana és una de les més riques del món, amb el 17,3% o més de les espècies conegudes. A més a més, s’ hi inclouen 16 espècies que és probable que siguin presents a Mèxic atesos els seus patrons de distribució.Checklist of sharks, rays and chimaeras (Chondrichthyes, Elasmobranchii, Holocephali) from Mexico We present an annotated checklist of the species of sharks, rays and chimaeras (chondrichthyan fishes) occurring in Mexican waters, based on a thorough review of the literature and electronic database searches, examination of museum collection specimens, and unpublished records obtained during fieldwork conducted in the last four years. The checklist contains information of at least 214 species of chondrichthyan fishes that occur in Mexican marine and brackish waters, assigned to 84 genera, 40 families and 14 orders. It includes eight species of chimaeras, 95 batoids and 111 sharks. Condrichthyan fauna in Mexico is one of the richest in the world, with almost 17.3% of the known species. An additional  16 species are included  as their occurrence in Mexican marine waters is probable according to distributional patterns.Se presenta un listado anotado de las especies de tiburones, rayas y quimeras (Condrictios) que han sido registrados en las aguas territoriales de México, basado en revisiones de bases de datos, literatura, examinación física de los especímenes de colecciones científicas y de registros de ejemplares recolectados en campo durante los últimos cuatro años y que no han sido publicados. El listado contiene información de al menos 214 especies de condrictios que se han registrado en las aguas marinas y salobres de México, pertenecientes a 84 géneros, 40 familias y 14 órdenes. Se incluyen ocho especies de quimeras, 95 de batoideos y 111 de tiburones. La condrictiofauna mexicana es una de las más ricas a nivel mundial, con al menos 17.3% de las especies conocidas. Adicionalmente, 16 especies, se incluyen como especies probables que ocurran en México debido a sus patrones de distribución.Palabras clave: Condrictios, Elasmobranquios, Batoideos, Quimeras, México

Complex evolutionary history of the Mexican stoneroller Campostoma ornatum Girard, 1856 (Actinopterygii: Cyprinidae)

<p>Abstract</p> <p>Background</p> <p>Studies of the phylogeography of Mexican species are steadily revealing genetic patterns shared by different species, which will help to unravel the complex biogeographic history of the region. <it>Campostoma ornatum </it>is a freshwater fish endemic to montane and semiarid regions in northwest Mexico and southern Arizona. Its wide range of distribution and the previously observed morphological differentiation between populations in different watersheds make this species a useful model to investigate the biogeographic role of the Sierra Madre Occidental and to disentangle the actions of Pliocene tecto-volcanic processes <it>vs </it>Quaternary climatic change. Our phylogeographic study was based on DNA sequences from one mitochondrial gene (<it>cytb</it>, 1110 bp, n = 285) and two nuclear gene regions (S7 and RAG1, 1822 bp in total, n = 56 and 43, respectively) obtained from 18 to 29 localities, in addition to a morphological survey covering the entire distribution area. Such a dataset allowed us to assess whether any of the populations/lineages sampled deserve to be categorised as an evolutionarily significant unit.</p> <p>Results</p> <p>We found two morphologically and genetically well-differentiated groups within <it>C. ornatum</it>. One is located in the northern river drainages (Yaqui, Mayo, Fuerte, Sonora, Casas Grandes, Santa Clara and Conchos) and another one is found in the southern drainages (Nazas, Aguanaval and Piaxtla). The split between these two lineages took place about 3.9 Mya (CI = 2.1-5.9). Within the northern lineage, there was strong and significant inter-basin genetic differentiation and also several secondary dispersal episodes whit gene homogenization between drainages. Interestingly, three divergent mitochondrial lineages were found in sympatry in two northern localities from the Yaqui river basin.</p> <p>Conclusions</p> <p>Our results indicate that there was isolation between the northern and southern phylogroups since the Pliocene, which was related to the formation of the ancient Nazas River paleosystem, where the southern group originated. Within groups, a complex reticulate biogeographic history for <it>C. ornatum </it>populations emerges, following the taxon pulse theory and mainly related with Pliocene tecto-volcanic processes. In the northern group, several events of vicariance promoted by river or drainage isolation episodes were found, but within both groups, the phylogeographic patterns suggest the occurrence of several events of river capture and fauna interchange. The Yaqui River supports the most diverse populations of <it>C. ornatum</it>, with several events of dispersal and isolation within the basin. Based on our genetic results, we defined three ESUs within <it>C. ornatum </it>as a first attempt to promote the conservation of the evolutionary processes determining the genetic diversity of this species. They will likely be revealed as a valuable tool for freshwater conservation policies in northwest Mexico, where many environmental problems concerning the use of water have rapidly arisen in recent decades.</p

Effect of alirocumab on mortality after acute coronary syndromes. An analysis of the ODYSSEY OUTCOMES randomized clinical trial

Background: Previous trials of PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitors demonstrated reductions in major adverse cardiovascular events, but not death. We assessed the effects of alirocumab on death after index acute coronary syndrome. Methods: ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) was a double-blind, randomized comparison of alirocumab or placebo in 18 924 patients who had an ACS 1 to 12 months previously and elevated atherogenic lipoproteins despite intensive statin therapy. Alirocumab dose was blindly titrated to target achieved low-density lipoprotein cholesterol (LDL-C) between 25 and 50 mg/dL. We examined the effects of treatment on all-cause death and its components, cardiovascular and noncardiovascular death, with log-rank testing. Joint semiparametric models tested associations between nonfatal cardiovascular events and cardiovascular or noncardiovascular death. Results: Median follow-up was 2.8 years. Death occurred in 334 (3.5%) and 392 (4.1%) patients, respectively, in the alirocumab and placebo groups (hazard ratio [HR], 0.85; 95% CI, 0.73 to 0.98; P=0.03, nominal P value). This resulted from nonsignificantly fewer cardiovascular (240 [2.5%] vs 271 [2.9%]; HR, 0.88; 95% CI, 0.74 to 1.05; P=0.15) and noncardiovascular (94 [1.0%] vs 121 [1.3%]; HR, 0.77; 95% CI, 0.59 to 1.01; P=0.06) deaths with alirocumab. In a prespecified analysis of 8242 patients eligible for ≥3 years follow-up, alirocumab reduced death (HR, 0.78; 95% CI, 0.65 to 0.94; P=0.01). Patients with nonfatal cardiovascular events were at increased risk for cardiovascular and noncardiovascular deaths (P<0.0001 for the associations). Alirocumab reduced total nonfatal cardiovascular events (P<0.001) and thereby may have attenuated the number of cardiovascular and noncardiovascular deaths. A post hoc analysis found that, compared to patients with lower LDL-C, patients with baseline LDL-C ≥100 mg/dL (2.59 mmol/L) had a greater absolute risk of death and a larger mortality benefit from alirocumab (HR, 0.71; 95% CI, 0.56 to 0.90; Pinteraction=0.007). In the alirocumab group, all-cause death declined wit h achieved LDL-C at 4 months of treatment, to a level of approximately 30 mg/dL (adjusted P=0.017 for linear trend). Conclusions: Alirocumab added to intensive statin therapy has the potential to reduce death after acute coronary syndrome, particularly if treatment is maintained for ≥3 years, if baseline LDL-C is ≥100 mg/dL, or if achieved LDL-C is low. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01663402

Lista patrón de los tiburones, rayas y quimeras (Chondrichthyes, Elasmobranchii, Holocephali) de México

Checklist of sharks, rays and chimaeras (Chondrichthyes, Elasmobranchii, Holocephali) from Mexico We present an annotated checklist of the species of sharks, rays and chimaeras (chondrichthyan fishes) occurring in Mexican waters, based on a thorough review of the literature and electronic database searches, examination of museum collection specimens, and unpublished records obtained during fieldwork conducted in the last four years. The checklist contains information of at least 214 species of chondrichthyan fishes that occur in Mexican marine and brackish waters, assigned to 84 genera, 40 families and 14 orders. It includes eight species of chimaeras, 95 batoids and 111 sharks. Condrichthyan fauna in Mexico is one of the richest in the world, with almost 17.3% of the known species. An additional 16 species are included as their occurrence in Mexican marine waters is probable according to distributional patterns. Data published through GBIF [doi:10.15470/hrl1kv

Global phylogeography of the dolphinfish (Coryphaena hippurus) : the influence of large effective population size and recent dispersal on the divergence of a marine pelagic cosmopolitan species

Pelagic fish that are distributed circumtropically are characterised by a low population structure level as a result of a high capacity for dispersion and large population sizes. Nevertheless, historical and contemporary processes, including past demographic and/or range expansions, secondary contact, dispersal, gene flow, and the achievement of large effective population sizes, may play a part in the detection of divergence signals, especially in the case of tropical pelagic species, whose distribution range depends strongly on the sea surface temperature. The connectivity and historical demography of Atlantic, Indian, Pacific and Mediterranean populations of dolphinfish (Coryphaena hippurus) was studied using partial sequences of the mitochondrial DNA NADH dehydrogenase subunit 1 (ND1). AMOVA analyses revealed significant inter-oceanic divergence with three phylogroups located in the Indo-Pacific, Eastern Atlantic, and Mediterranean Sea, the last one being the most divergent. However, it was not possible to clearly observe any genetic differentiation between the Indo-Pacific and Atlantic populations, as has been reported for most tropical pelagic species of tuna and billfishes. This supports the assumption of recent dispersal among basins facilitated by the actual continuous distribution of dolphinfish populations. Moreover, the lack of a divergence signal for populations separated by the Panamanian Isthmus reveals that genetic drift does not exert a strong influence on tropical pelagic species with large effective population sizes