82 research outputs found

    University Sustainability: Assessing College Sustainability Rating Systems

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    This paper seeks to assess the three major university sustainability rating systems in the United States on their ability to drive positive sustainability outcomes. Since the mid-2000s the Association for Advancement of Sustainability in Higher Education, the Princeton Review, and the Sierra Club have attempted to rate universities on their sustainability policies and practices. A wide range of actions are rated by these organizations, from energy usage to transportation to procurement to academic offerings in the field of sustainability. This analysis shows that each organization values sustainability in different ways – for example, academics/co-curricular activities accounted for anywhere from 16%-49% of the total points available across the three rating systems. This paper also measured criteria in terms of inputs versus outputs, where inputs measure actions taken, outputs measure results or outcomes – a question of vision versus execution. There is a greater emphasis on input criteria than output criteria in overall scoring across each rating system, despite the fact that outputs are more suitable for measuring actual progress on sustainability. I offer suggestions as to how to adjust criteria to be more results-oriented

    A review of expansive phenomena in Wagenburg North Tunnel

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    The paper deals on tunnelling and swelling in anhydritic-gypsiferous claystones. The geology of the Gipskeuper in Baden-Württemberg (Germany) and the phenomenology of expansions in Wagenburg North tunnel are described. Consistent swelling triggering events, mechanisms and exhaustion causes were identified using a thermo-hydro-chemo-mechanical theoretical analysis. It is suggested that long-term swelling in tunnels excavated through anhydritic-gypsiferous claystones is a result of solvent-way gypsum crystal growth due to ventilation induced groundwater evaporation and rock drying; an opposite concept to the usual consequences of drying in argillaceous materials, which causes shrinkage strains

    A public health response against Strongyloides stercoralis : time to look at soil-transmitted helminthiasis in full

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    Strongyloides stercoralis infections have a worldwide distribution with a global burden in terms of prevalence and morbidity that is largely ignored. A public health response against soil-transmitted helminth (STH) infections should broaden the strategy to include S. stercoralis and overcome the epidemiological, diagnostic, and therapeutic challenges that this parasite poses in comparison to Ascaris lumbricoides, Trichuris trichiura, and hookworms. The relatively poor sensitivity of single stool evaluations, which is further lowered when quantitative techniques aimed at detecting eggs are used, also complicates morbidity evaluations and adequate drug efficacy measurements, since S. stercoralis is eliminated in stools in a larval stage. Specific stool techniques for the detection of larvae of S. stercoralis, like Baermann's and Koga's agar plate, despite superiority over direct techniques are still suboptimal. New serologies using recombinant antigens and molecular-based techniques offer new hopes in those areas. The use of ivermectin rather than benzimidazoles for its treatment and the need to have curative regimens rather than lowering the parasite burden are also unique for S. stercoralis in comparison to the other STH due to its life cycle, which allows reproduction and amplification of the worm burden within the human host. The potential impact on STH of the benzimidazoles/ivermectin combinations, already used for control/elimination of lymphatic filariasis, should be further evaluated in public health settings. While waiting for more effective single-dose drug regimens and new sensitive diagnostics, the evidence and the tools already available warrant the planning of a common platform for STH and S. stercoralis control

    A Comparative Study of the Spatial Distribution of Schistosomiasis in Mali in 1984–1989 and 2004–2006

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    Geostatistical maps are increasingly being used to plan neglected tropical disease control programmes. We investigated the spatial distribution of schistosomiasis in Mali prior to implementation of national donor-funded mass chemotherapy programmes using data from 1984–1989 and 2004–2006. The 2004–2006 dataset was collected after 10 years of schistosomiasis control followed by 12 years of no control. We found that national prevalence of Schistosoma haematobium and S. mansoni was not significantly different in 2004–2006 compared to 1984–1989 and that the spatial distribution of both infections was similar in both time periods, to the extent that models built on data from one time period could accurately predict the spatial distribution of prevalence of infection in the other time period. This has two main implications: that historic data can be used, in the first instance, to plan contemporary control programmes due to the stability of the spatial distribution of schistosomiasis; and that a decade of donor-funded mass distribution of praziquantel has had no discernable impact on the burden of schistosomiasis in subsequent generations of Malians, probably due to rapid reinfection

    Climate change, malaria and neglected tropical diseases: a scoping review

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    To explore the effects of climate change on malaria and 20 neglected tropical diseases (NTDs), and potential effect amelioration through mitigation and adaptation, we searched for papers published from January 2010 to October 2023. We descriptively synthesised extracted data. We analysed numbers of papers meeting our inclusion criteria by country and national disease burden, healthcare access and quality index (HAQI), as well as by climate vulnerability score. From 42 693 retrieved records, 1543 full-text papers were assessed. Of 511 papers meeting the inclusion criteria, 185 studied malaria, 181 dengue and chikungunya and 53 leishmaniasis; other NTDs were relatively understudied. Mitigation was considered in 174 papers (34%) and adaption strategies in 24 (5%). Amplitude and direction of effects of climate change on malaria and NTDs are likely to vary by disease and location, be non-linear and evolve over time. Available analyses do not allow confident prediction of the overall global impact of climate change on these diseases. For dengue and chikungunya and the group of non-vector-borne NTDs, the literature privileged consideration of current low-burden countries with a high HAQI. No leishmaniasis papers considered outcomes in East Africa. Comprehensive, collaborative and standardised modelling efforts are needed to better understand how climate change will directly and indirectly affect malaria and NTDs

    Triple Co-Administration of Ivermectin, Albendazole and Praziquantel in Zanzibar: A Safety Study

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    This paper describes how the use of three drugs which are used separately in mass drug distribution programmes when given together appear safe for use in large populations which have been previously treated with the same drugs separately (Mectizan [ivermectin], albendazole and praziquantel). The target diseases—lymphatic filariasis, soil-transmitted worms and schistosomiasis—were prevalent in Zanzibar up to 2000 but have been largely controlled by mass drug administration. The Ministry of Health and Social Welfare, with the support of WHO, initiated a small scale trial in a population of triple therapy in over 5,000 people initially in two sites, and having found there were no severe adverse events associated with the combined treatment then upscaled to treat the whole of the eligible population of over 700,000. Similarly, there were no severe adverse events. This is the first time the three drugs have been used together at the same time at scale in Africa and provide a basis for expansion of integrated preventive chemotherapy of helminths (worms). The next steps need to be initiated in populations which have heavier worm loads and such interventions need to be subject to close monitoring and ethical review

    Papel de los biomarcadores fecales en la enfermedad inflamatoria intestinal: ¿qué tan útiles son?

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    La enfermedad inflamatoria intestinal (EII) es una alteración gastrointestinal crónica, cuyas formas más comunes son la colitis ulcerativa (CU) y la enfermedad de Crohn (EC), ambas con gran impacto en la calidad de vida de los pacientes. El aumento en la prevalencia de esta condición en los últimos años ha creado la necesidad de implementar herramientas diagnósticas y de seguimiento menos invasivas y fácilmente disponibles. Por este motivo, ha sido de gran interés la introducción de los biomarcadores fecales, los cuales han facilitado la toma de decisiones en esta entidad. El objetivo de la siguiente revisión es determinar la evidencia disponible sobre la utilidad de los biomarcadores fecales y su aplicación en la práctica clínica
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