90 research outputs found
The Development of Body Image in Dancers: Examining Gesture\u27s Role in Conveying Body Image
Body image and body dissatisfaction is an issue in western countries. Many females, especially dancers, have been objectified by a cultural stereotype of a thin body and being referred to as “skin and bones”. Recently, body disturbances have been reported in children as young as six years old. Children this young may be unaware that they are expressing these negative thoughts about their bodies and thus, the measures assessing body image are challenging to analyze. Another line of research has shown that children spontaneously produce hand gestures when narrating stories, solving math problems, or explaining scientific ideas. Moreover, children convey ideas in their hand gestures before they can convey these ideas in the verbal modality. Gesture, along with the verbal modality, is a useful tool when assessing what a child knows or is thinking, especially when those ideas are new. We examined if young dancers display a negative body image and whether or not there are age related changes in body image when comparing the younger dancers to the older ones. In addition, we examined through gesture and speech, whether or not additional information about one\u27s body image can be assessed and if these responses change across development. Using a cross sectional design, body image was measured in dancers using one of the following tests, the Body Assessment (BIA) (Williamson, et al, 1989), the Body Image Assessment for Preadolescents (BIA-P), or the Body Image Assessment for Children (BIA-C) (Veron-Guidry & Williamson, 1996). In addition, participant’s gestures were examined through follow-up questions on the BIA measure. While there was not a statistical significance on the BIA across age groups, children displayed a more negative body image in comparison to the other age groups. Gesture was also found to convey substantial information about a dancer’s body image. The findings suggest that it is important to look at children’s gestures, along with their speech, to determine a more accurate representation about body image
Visual snow: A neuro-ophthalmic syndrome
Background: The visual snow syndrome (VSS) is a rare disease characterized by persistent positive visual phenomena that are enigmatic and may be underestimated. It manifests as the perception of tiny, simultaneous, diffuse, and mobile dots frequently throughout the visual field. Although it affects brain networks, ocular examination is also indicated. This paper was aimed to review recent studies on VSS to identify the best clinical approach.
Methods: In this narrative review, PubMed/Medline, Directory of Open Access Journals, and Embase were searched using the following terms: “Visual snow”, “Persistent aura”, “Persistent positive visual phenomena”, “Visual aura”, “Migraine”, “TV static”, “Migraine aura status”, and “Visual disturbance”. We searched relevant publications from January 2014 to January 2021 to find the best clinical approach.
Results: VSS may be reconstituted as a distinct entity, although the symptoms may be consistent with typical migraine visual aura. For approximately two-thirds of patients, symptoms worsen and reduce their ability for activities of daily living. It often causes psychogenic detriment of the patient and their capacity to function socially and vocationally. Comprehensive history-taking and ocular examination are required to rule out other causes. However, all ocular and radiological findings may be normal.
Conclusions: VSS is a neuro-ophthalmic disorder characterized by continuous chronic and recurrent visual disturbances that involve the entire visual field and may respond to empiric antimigraine or anti-seizure treatments. It may reduce the ability for activities of daily living; therefore, proper diagnosis by eye care professionals is necessary to determine its diagnosis and management
Combined implantation of toric and spherical intraocular lenses for low corneal astigmatism correction
Background: This study compared outcomes of combined toric versus spherical intraocular lens (IOL) implantation in patients with low corneal astigmatism.
Methods: In this retrospective contralateral study, patients with corneal astigmatism who received combined toric (FIL 611 T, Soleko, Rome, Italy) and spherical IOL (FIL 611 T, Soleko, Rome, Italy) implants were recruited. Eyes were examined preoperatively and then again 3 months postoperatively. Postoperatively, uncorrected distance visual acuity (UCDVA), residual astigmatism, and spherical equivalent (SE) were compared between the toric IOL-implanted eyes and the spherical IOL-implanted fellow eyes.
Results: Among the 46 included cases (age 69 ± 12.7 years [mean± standard deviation]; range: 60‒78 years), 86.9% of eyes (n = 40) in the toric IOL group had a postoperative refractive cylinder of ≤ 0.25 diopters (D), compared with 4.3% (n = 2) of eyes in the spherical IOL group. Both groups showed a statistically significant reduction in refractive cylinder and improvement in UCDVA after cataract surgery (both P = 0.01). Similarly, toric IOLs were superior (69.6%) to spherical lenses (2.2%) in obtaining a SE of ≤ 0.25 D.
Conclusions: To our knowledge, no previous study had sought to compare low-power toric and spherical IOLs in low corneal astigmatism in the same patient's eyes. Our findings suggest that low-power toric IOLs may result in good refractive outcomes as compared with spherical IOLs implanted in the fellow eye of the same patient, although both result in significant UCDVA improvement. Wellâ€designed clinical research studies with a longer follow-up and more participants are necessary to confirm these findings
Ethical and Forensic Issues in the Medico-Legal and Psychological Assessment of Women Asylum Seekers
Asylum-seeking migrants represent a vulnerable segment of the population, and among them, women constitute an even more vulnerable group. Most of these women and girls have been exposed to threats, coercion, and violence of many kinds, including rape, forced prostitution, harassment, sexual slavery, forced marriage and pregnancy, female genital mutilation/excision, and/or other violations of their rights (e.g., deprivation of education, prohibition to work, etc.). The perpetrators of the violence from which they flee are often their own families, partners, and even institutional figures who should be in charge of their protection (such as police officers). In the process for the acceptance/rejection of an asylum application, the forensic and psychological certification can make the difference between successful and unsuccessful applications, as it can support the credibility of the asylum seeker through an assessment of the degree of compatibility between the story told and the diagnostic and forensic evidence. This is why constant and renewed reflection on the ethical, forensic, and methodological issues surrounding medico-legal and psychological certification is essential. This article aims to propose some reflections on these issues, starting from the experience of the inward healthcare service dedicated to Migrant Victims of Maltreatment, Torture, and Female Genital Mutilation operating since 2018 at the Institute of Forensic Medicine of the University Hospital of Palermo
Towards the study of alteration patinas on the marble surface of a Renaissance sculptural group from the Museum of Ancient Art (Castello Sforzesco, Milan)
Candida albicans identification: comparison among nine phenotypic systems and a multiplex PCR
Background. Candida albicans is the most common fungal pathogen isolated from clinical samples and is also the most common yeast species carried as a commensal by healthy individuals although some non-C. albicans species account for an important number of infections.
Objectives. To compare nine phenotypic systems for C. albicans identification [API 20C AUX; RapID Yeast Identification panel (RYIP); Vitek2 ID-YST system; chromogenic media, CHROMagar, Oxoid Chromogenic Candida Agar (OCCA), Candida ID2, Candida Identification Agar, CandiSelect 4, and Chromalbicans Agar] with multiplex PCR.
Patients/Methods. A collection of 390 yeast strains was obtained by routine isolation from oral and vaginal swabs. All of the yeasts isolated were tested for germ tube formation, and then submitted to a multiplex PCR protocol tested in previous studies, and to nine phenotypical commercial methods, together with the reference ATCC strains. Comparison was limited to the ability of the tests to identify C. albicans.
Results. 253 isolates were provisionally identified as C. albicans by germ tube, and their identities were further confirmed with the multiplex PCR. Sensitivity of phenotypical systems ranged from 81.9% (Vitek2) to 87.7% (Candida ID2 e CHROMagar). For specificity,
the highest value was 96.8% for Candida ID2, and the lowest value (75.1%) was for Chromalbicans Agar.
Conclusions. Although with differences in discriminatory power, the methods tested showed overall acceptable levels of sensitivity and specificity respect to the multiplex PCR; therefore, all could be useful for C. albicans identification where molecular differentiation is not available
PROCESSOS DE CAPACITAÇÃO DE GESTORES E PROFISSIONAIS NA IMPLEMENTAÇÃO DA ESTRATÉGIA E-SUS ATENÇÃO PRIMÁRIA
Objective: To analyze the training processes of managers for the implementation of the e-SUS Primary Care strategy in municipalities in Minas Gerais. Method: Data collection took place by sending an online websurvey questionnaire to the managers responsible for implementing the strategy in the selected municipalities. Results: Data were processed using the statistical software Statistical Package for the Social Sciences (SPSS) 21.0. A total of 114 municipalities in Minas participated in the study, about 71.9% of them said they were trained to perform the function and in 52.6% of the municipalities training activities were not carried out for the adoption/use of the systems for professionals. The process of implementing the e-SUS Primary Care strategy in Minas Gerais, despite the evolutions, presents weaknesses in the qualification process of professionals who use the systems. Conclusion: It is necessary to establish solid and structured qualification processes that meet the precepts of permanent educationObjetivo: Analizar los procesos de formación de gestores para la implementación de la estrategia e-SUS de Atención Primaria en municipios de Minas Gerais. Método: La recopilación de datos se realizó mediante el envío de un cuestionario de encuesta en línea a los gerentes responsables de implementar la estrategia en los municipios seleccionados. Resultados: Los datos fueron procesados con el programa estadístico Statistical Package for the Social Sciences (SPSS) 21.0. Participaron del estudio 114 municipios de Minas, de los cuales cerca del 71,9% dijeron estar capacitados para desempeñar la función y en el 52,6% de los municipios no hubo actividades de capacitación para la adopción/uso de los sistemas para profesionales. El proceso de implementación de la estrategia de Atención Primaria e-SUS en Minas Gerais, a pesar de las evoluciones, presenta debilidades en el proceso de calificación de los profesionales que utilizan los sistemas. Conclusión: Es necesario establecer procesos de calificación sólidos y estructurados que respondan a los preceptos de la educación continuaObjetivo: analisar processos de capacitação de gestores e profissionais de saúde na implementação da estratégia e-SUS Atenção Primária em municípios de Minas Gerais. Método: foram enviados questionários on-line, do tipo websurvey, aos gestores responsáveis pela implantação da estratégia nos municípios selecionados; os dados foram processados com auxílio do software estatístico Statistical Package for the Social Sciences 21.0. Resultados: participaram do estudo gestores de 114 municípios mineiros. Cerca de 71,9% deles afirmaram ter participado de processos de capacitação para desempenho da função, e em 52,6% dos municípios não foram realizados treinamentos para adoção/utilização dos sistemas aos profissionais de saúde. Conclusão: o processo de implementação da estratégia e-SUS Atenção Primária em Minas Gerais, apesar das evoluções, apresenta fragilidades na adoção de processos de capacitação dos profissionais que utilizam os sistemas.
Descritores: Sistemas de Informação em Saúde. Atenção Primária à Saúde. Tecnologia da Informação. Capacitação em Serviço. Capacitação Profissional
Shanghai Fever: Not Only an Asian Disease
Objectives: To describe a case of Shanghai fever disease and to analyze other published reports in non-Asiatic countries, defining clinical characteristics and highlighting that this is not only an Asian disease. Study design: A computerized search without language restriction was conducted using PubMed and Scopus; all references listed were hand-searched to identify any other relevant literature. An article was considered eligible for inclusion in the systematic review if it reported cases with Shanghai fever described in non-Asiatic countries. Our case was also included in the analysis. Results: Ten articles reporting 10 cases of Shanghai fever disease were considered. Fever, diarrhea and ecthyma gangrenosum were the most frequent symptoms observed. Blood was the most common site of isolation for Pseudomonas aeruginosa. Three patients underwent surgery due to necrotizing enteritis and intestinal perforation. Meningitis was documented in one case. None of the patients received antipseudomonal antibiotics within 24 h of admission. The outcome was good in nine cases; only one patient died due to multiple organ failure from Pseudomonas sepsis. No common primary immune deficiency was identified in these patients. Extremely young age (<1 year) was the only host factor predisposing to Shanghai fever. Conclusions: It is important to shed light on this disease in non-Asiatic countries and take into account that it can also affect healthy children. Pediatricians, therefore, should consider Shanghai fever among diagnoses in children with community-onset diarrhea, fever and skin lesions suggestive of ecthyma gangrenosum to start an appropriate treatment sooner and to reduce the mortality in these children
Development and Implementation of the AIDA International Registry for Patients with Non-Infectious Scleritis
Introduction This article points out the design, methods, development and deployment of the international registry promoted by the AutoInflammatory Disease Alliance (AIDA) Network with the aim to define and assess paediatric and adult patients with immune-mediated scleritis. Methods This registry collects both retrospective and prospective real-world data from patients with non-infectious scleritis through the Research Electronic Data Capture (REDCap) tool and aims to promote knowledge and real-life evidence from patients enrolled worldwide; the registry also allows the collection of standardised data, ensuring the highest levels of security and anonymity of patients' data and flexibility to change according to scientific acquisitions over time. The communication with other similar registries has been also ensured in order to pursue the sustainability of the project with respect to the adaptation of collected data to the most diverse research projects. Results Since the launch of the registry, 99 centres have been involved from 20 countries and four continents. Forty-eight of the centres have already obtained a formal approval from their local ethics committees. At present, the platform counts 259 users (95 principal investigators, 160 site investigators, 2 lead investigators, and 2 data managers); the platform collects baseline and follow-up data using 3683 fields organised into 13 instruments, including patient's demographics, history, symptoms, trigger or risk factors, therapies and healthcare utilization. Conclusions The development of the AIDA International Registry for patients with non-infectious scleritis will allow solid research on this rare condition. Real-world evidence resulting from standardised real-life data will lead to the optimisation of routine clinical and therapeutic management, which are currently limited by the rarity of this ocular inflammatory condition
Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 Protocol
IDH1/2 mutations are common in acute myeloid leukemia (AML) and represent a therapeutic
target. The GIMEMA AML1516 observational protocol was designed to study the prevalence
of IDH1/2 mutations and associations with clinico-biological parameters in a cohort of Italian AML
patients. We analyzed a cohort of 284 AML consecutive patients at diagnosis, 139 females and
145 males, of a median age of 65 years (range: 19–86). Of these, 38 (14%) harbored IDH1 and
51 (18%) IDH2 mutations. IDH1/2 mutations were significantly associated with WHO PS >2 (p < 0.001)
and non-complex karyotype (p = 0.021) when compared to IDH1/2-WT. Furthermore, patients with
IDH1 mutations were more frequently NPM1-mutated (p = 0.007) and had a higher platelet count
(p = 0.036). At relapse, IDH1/2 mutations were detected in 6 (25%) patients. As per the outcome,
60.5% of IDH1/2-mutated patients achieved complete remission; overall survival and event-free
survival at 2 years were 44.5% and 36.1%, respectively: these rates were similar to IDH1/2-WT. In
IDH1/2-mutated patients, high WBC proved to be an independent prognostic factor for survival.
In conclusion, the GIMEMA AML1516 confirms that IDH1/2 mutations are frequently detected at
diagnosis and underlines the importance of recognizing IDH1/2-mutated cases up-front to offer the
most appropriate therapeutic strategy, given the availability of IDH1/2 inhibitors
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