Therapies in the fight against Covid-19

SARS-Cov-2 Coronavirus is a new emerging virus causing the COVID-19, a respiratory disease outbreak that started in China in December 2019. On January 30, 2020, the World Health Organization has declared this to be a public health emergency of international concern. By September 2020, COVID-19 has affected more than 33 millionin 210 countries and territories worldwide. In this review, we present an overview of the drugs and medicines to combat COVID-19 currently in the clinical trial. We summarize the challenges facing, and opportunities for the discovery of new therapies in this emergency situation

Les dyspareunies du post partum: un sujet non négligeable

La dyspareunie est une douleur éprouvée lors du rapport sexuel. Elle peut être superficielle ou profonde. Elle est fréquente en post partum et donc non négligeable. Elle a fait l’objet de plusieurs descriptions et plusieurs classifications.  Les étiologies sont nombreuses : infectieuses, traumatiques, hormonales, psychiques et autres. Le traitement de la dyspareunie se base sur le traitement de la cause organique et le traitement psychologique du conditionnement à la douleur qui persiste après le traitement médical

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020