2-[(1-Methyl-1H-pyrrol-2-yl)methyl­idene]propane­dinitrile

In the title compound, C9H7N3, the N-bound methyl group and vinyl H atom are syn. The 12 non-H atoms comprising the mol­ecule are essentially coplanar (r.m.s. deviation = 0.071 Å). Supra­molecular tapes feature in the crystal packing, orientated perpendicular to [10-1], and are formed by C—H⋯N inter­actions involving each cyano N atom. The tapes are connected into layers via π–π inter­actions occurring between translationally related pyrrole rings [ring centroid–centroid distance = 3.8754 (10) Å]; the layers stack along the b axis

Two polymeric 36-metal pure lanthanide nanosize clusters

973 Program [2011CBA00507, 2011CB932504]; National Natural Science Foundation of China [21131006]; Natural Science Foundation of Fujian ProvinceTwo rarely seen 2D coordination polymers based on huge 36-metal pure lanthanide clusters, {[Gd-36(NA)(36)(OH)(49)(O)(6)(NO3)(6)(N-3)(3)(H2O)(20)]Cl-2 center dot 28H(2)O}(n) (1) and {[Dy-36(NA)(36)(OH)(49)(O)(6)(NO3)(6)(N-3)(3-)(H2O)(20)]Cl-2 center dot 28H(2)O}(n) (2) (HNA = nicotinic acid), were synthesized and structurally characterized. The spherical Ln(36) skeleton can be viewed as the aggregation of one cyclohexane chair-like Ln(24) wheel and two identical tripod-like Ln(6) units. The coordination of the carboxylic groups of the NA ligands with the Ln(III) cations results in a square layer. Additionally, compound 1 possesses a large MCE of 39.66 J kg(-1) K-1 and compound 2 exhibits slow relaxation of the magnetization

Synthesis, Structure Optimization and Antifungal Screening of Novel Tetrazole Ring Bearing Acyl-Hydrazones

Azoles are generally fungistatic, and resistance to fluconazole is emerging in several fungal pathogens. In an attempt to find novel azole antifungal agents with improved activity, a series of tetrazole ring bearing acylhydrazone derivatives were synthesized and screened for their in vitro antifungal activity. The mechanism of their antifungal activity was assessed by studying their effect on the plasma membrane using flow cytometry and determination of the levels of ergosterol, a fungal-specific sterol. Propidium iodide rapidly penetrated a majority of yeast cells when they were treated with the synthesized compounds at concentrations just above MIC, implying that fungicidal activity resulted from extensive lesions of the plasma membrane. Target compounds also caused a considerable reduction in the amount of ergosterol. The results also showed that the presence and position of different substituents on the phenyl ring of the acylhydrazone pendant seem to play a role on the antifungal activity as well as in deciding the fungistatic and fungicidal nature of the compounds

Synthesis, Structure Optimization and Antifungal Screening of Novel Tetrazole Ring Bearing Acyl-Hydrazones

Azoles are generally fungistatic, and resistance to fluconazole is emerging in several fungal pathogens. In an attempt to find novel azole antifungal agents with improved activity, a series of tetrazole ring bearing acylhydrazone derivatives were synthesized and screened for their <em>in vitro</em> antifungal activity. The mechanism of their antifungal activity was assessed by studying their effect on the plasma membrane using flow cytometry and determination of the levels of ergosterol, a fungal-specific sterol. Propidium iodide rapidly penetrated a majority of yeast cells when they were treated with the synthesized compounds at concentrations just above MIC, implying that fungicidal activity resulted from extensive lesions of the plasma membrane. Target compounds also caused a considerable reduction in the amount of ergosterol. The results also showed that the presence and position of different substituents on the phenyl ring of the acylhydrazone pendant seem to play a role on the antifungal activity as well as in deciding the fungistatic and fungicidal nature of the compounds

Self-decoration of Pt metal particles on TiO2 nanotubes used for highly efficient photocatalytic H2 production

Pt decorated TiO2 has, over the past decades, been a key material for photocatalytic hydrogen production. The present work shows that growing anodic self-organized TiO2 nanotubes from Ti–Pt alloy with a low Pt content of 0.2 at% leads to oxide nanotube layers that are self-decorated with Pt nanoparticles of 4–5 nm in diameter. The average particle spacing is in the range of ~50 nm and is partially adjustable by the anodization conditions. This intrinsic decoration of TiO2 nanotubes with Pt leads to a highly active photocatalyst for the production of H2 under UV or visible light conditions

N-Acetyl-N-[2,4-dicyano-1-(4-methoxyphenyl)-9,10-dihydrophenanthren-3-yl]acetamide

In the title compound, C27H21N3O3, the cyclohexa-1,3-diene ring has a screw-boat conformation, and the fused ring system is folded, the dihedral angle between the outer benzene rings being 27.61 (6)°. The N-acetylacetamide residue (r.m.s. deviation = 0.0935 Å) has an anti conformation and is essentially perpendicular to the benzene ring to which it is connected [dihedral angle = 89.14 (6)°]; the methoxybenzene group is also twisted out of this ring [dihedral angle = 59.47 (7)°]. The three-dimensional architecture is consolidated by C—H...O and C—H...π interactions

Group 12 Metal Complexes of Semirigid 2,6-Pyridinediyl­bis(3-pyridinyl)­methanone: Role of Counteranions and Solvent in Product Formation

In a series of nine group 12 metal complexes of 2,6-pyridine­diyl­bis­(3-pyridinyl)­methanone (abbreviated as L), namely, [Cd­(L)₂­Cl₂] (<b>1</b>), [Cd­(L)₂­(NO₃)₂]·3.5H₂O (<b>2</b>), [Cd­(L)₂­(H₂O)₂]­(NO₃)₂ (<b>3</b>), [Cd­(L)₂­(H₂O)₂]­(ClO₄)₂·H₂O (<b>4</b>), {[Cd­(L)­(H₂O)₂]­(ClO₄)₂·1.5H₂O}_∞ (<b>5</b>), {[Cd­(L)₂­SO_4­(H₂O)]·2.8H₂O}_∞ (<b>6</b>), [Cd­(L)_2­(CH₃­CO₂)₂]_∞ (<b>7</b>), [Zn­(L)₂­(CH₃­CO₂)₂]_∞ (<b>8</b>), and [Hg­(L)₂­(CH₃­CO₂)₂]_∞ (<b>9</b>), the semirigid multidentate ligand L exhibits flexible ligation modes I–IV in response to the cooperative effect of counteranions and solvent medium, leading to mononuclear (<b>1</b>–<b>4</b>), helical-chain (<b>6</b>), zigzag-chain (<b>7</b>), and 3D net (<b>5</b>) coordination motifs. The presence of the ancillary aqua ligand is essential for the crystallization of <b>3</b> and <b>5</b> by addition of deionized water to an organic mixed-solvent medium containing <b>2</b> and <b>4</b>, respectively. The acetate complexes <b>7</b> (Cd²⁺), <b>8</b> (Zn²⁺), and <b>9</b> (Hg²⁺) are isostructural. Unconventional anion−π­(pyridine), CO···CO, O­(NO₃^–/ClO₄^–)···CO, and cohesive nitrate···nitrate interactions are manifested in supramolcular aggregations of the present series of crystalline complexes