A hybrid GA–PS–SQP method to solve power system valve-point economic dispatch problems

This study presents a new approach based on a hybrid algorithm consisting of Genetic Algorithm (GA), Pattern Search (PS) and Sequential Quadratic Programming (SQP) techniques to solve the well-known power system Economic dispatch problem (ED). GA is the main optimizer of the algorithm, whereas PS and SQP are used to fine tune the results of GA to increase confidence in the solution. For illustrative purposes, the algorithm has been applied to various test systems to assess its effectiveness. Furthermore, convergence characteristics and robustness of the proposed method have been explored through comparison with results reported in literature. The outcome is very encouraging and suggests that the hybrid GA–PS–SQP algorithm is very efficient in solving power system economic dispatch problem

Exceptional Points of Degeneracy in Periodic Coupled Waveguides and the Interplay of Gain and Radiation Loss: Theoretical and Experimental Demonstration

We present a novel paradigm for dispersion engineering in coupled transmission lines (CTLs) based on exceptional points of degeneracy (EPDs). We develop a theory for fourth-order EPDs consisting of four Floquet-Bloch eigenmodes coalescing into one degenerate eigenmode. We present unique wave propagation properties associated to the EPD and develop a figure of merit to assess the practical occurrence of fourth-order EPDs in CTLs with tolerances and losses. We experimentally verify for the first time the existence of a fourth EPD (the degenerate band edge), through dispersion and transmission measurements in microstrip-based CTLs at microwave frequencies. In addition, we report that based on experimental observation and the developed figure of merit, the EPD features are still observable in structures that radiate (leak energy away), even in the presence of fabrication tolerances and dissipative losses. We investigate the gain and loss balance regime in CTLs as a mean of recovering an EPD in the presence of radiation and/or dissipative losses, without necessarily resorting to Parity-Time (PT)-symmetry regimes. The versatile EPD concept is promising in applications such as high intensity and power-efficiency oscillators, spatial power combiners, or low-threshold oscillators and opens new frontiers for boosting the performance of large coherent sources

Metallothionein induction reduces caspase-3 activity and TNFα levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats

Hippocampal integrity is essential for cognitive functions. On the other hand, induction of metallothionein (MT) by ZnSO4 and its role in neuroprotection has been documented. The present study aimed to explore the effect of MT induction on carmustine (BCNU)-induced hippocampal cognitive dysfunction in rats. A total of 60 male Wistar albino rats were randomly divided into four groups (15/group): The control group injected with single doses of normal saline (i.c.v) followed 24 h later by BCNU solvent (i.v). The second group administered ZnSO4 (0.1 µmol/10 µl normal saline, i.c.v, once) then BCNU solvent (i.v) after 24 h. Third group received BCNU (20 mg/kg, i.v, once) 24 h after injection with normal saline (i.c.v). Fourth group received a single dose of ZnSO4 (0.1 µmol/10 µl normal saline, i.c.v) then BCNU (20 mg/kg, i.v, once) after 24 h. The obtained data revealed that BCNU administration resulted in deterioration of learning and short-term memory (STM), as measured by using radial arm water maze, accompanied with decreased hippocampal glutathione reductase (GR) activity and reduced glutathione (GSH) content. Also, BCNU administration increased serum tumor necrosis factor-alpha (TNFα), hippocampal MT and malondialdehyde (MDA) contents as well as caspase-3 activity in addition to histological alterations. ZnSO4 pretreatment counteracted BCNU-induced inhibition of GR and depletion of GSH and resulted in significant reduction in the levels of MDA and TNFα as well as the activity of caspase-3. The histological features were improved in hippocampus of rats treated with ZnSO4 + BCNU compared to only BCNU-treated animals. In conclusion, MT induction halts BCNU-induced hippocampal toxicity as it prevented GR inhibition and GSH depletion and counteracted the increased levels of TNFα, MDA and caspase-3 activity with subsequent preservation of cognition

Optimal conditions for olive mill wastewater treatment using ultrasound and advanced oxidation processes

© 2019 Elsevier B.V. The treatment of olive mill wastewater (OMW) in Jordan was investigated in this work using ultrasound oxidation (sonolysis) combined with other advanced oxidation processes such as ultraviolet radiation, hydrogen peroxide (H2O2) and titanium oxide (TiO2) catalyst. The efficiency of the combined oxidation process was evaluated based on the changes in the chemical oxygen demand (COD). The results showed that 59% COD removal was achieved within 90 min in the ultrasound /UV/TiO2 system. A more significant synergistic effect was observed on the COD removal efficiency when a combination of US/UV/TiO2 (sonophotocatalytic) processes was used at low ultrasound frequency. The results were then compared with the COD values obtained when each of these processes was used individually. The effects of different operating conditions such as, ultrasound power, initial COD concentration, the concentration of TiO2, frequency of ultrasound, and temperature on the OMW oxidation efficiency were studied and evaluated. The effect of adding a radical scavenger (sodium carbonate) on the OMW oxidation efficiency was investigated. The results showed that the sonophotocatalytic oxidation of OMW was affected by the initial COD, acoustic power, temperature and TiO2 concentration. The sonophotocatalytic oxidation of OMW increased with increasing the ultrasound power, temperature and H2O2 concentration. Sonolysis at frequency of 40 kHz combined with photocatalysis was not observed to have a significant effect on the OMW oxidation compared to sonication at frequency of 20 kHz. It was also found that the OMW oxidation was suppressed by the presence of the radical scavenger. The COD removal efficiency increased slightly with the increase of TiO2 concentration up to certain point due to the formation of oxidizing species. At ultrasound frequency of 20 kHz, considerable COD reduction of OMW was reported, indicating the effectiveness of the combined US/UV/TiO2 process for the OMW treatment

The social and economic impacts of e-hailing application in Malaysia: A review

E-hailing is a service that allows users to book a journey online and provides a platform for users to interact with E-hailing companies. E-hailing service in Malaysia was launched in January 2018. Growing population and rising migration from rural to urban areas have put a strain on quality of life for Malaysia's population. The service is available in Malaysia. It has so far had success. E-hailing services have become more popular than traditional taxis for a variety of reasons. Customers are likely to seek out these providers' services as long as they pay close attention to their needs, solicit feedback often, and improve the quality of the services they give. Mobile applications developed by e-hailing businesses have had a significant influence on the taxi industry and public transportation in the last few years. Experts examined the impact of e-Hailing services on consumers, drivers and the public economy. Economics service created a lot of work prospects for drivers. Taxi industry struggling to keep up with E-Hailing system which put it under threat, as it cuts in taxi industry's profits. All e-hailing drivers must now obtain Public Service Vehicle (PSV) permits, but they complained that the regulations were too strict. Many of these driver-partners used E-hailing as a method to earn supplemental money in addition to driving. In the next several years, the way people move around in cities is anticipated to alter drastically. The conventional marketplace is being replaced by the online transaction as a method of conducting business. E-hailing in Malaysia today, as an alternative to private and public transportation, may be summed up by pointing out its increasing use

CDBFIP: Common Database Forensic Investigation Processes for Internet of Things

Database forensics is a domain that uses database content and metadata to reveal malicious activities on database systems in an Internet of Things environment. Although the concept of database forensics has been around for a while, the investigation of cybercrime activities and cyber breaches in an Internet of Things environment would benefit from the development of a common investigative standard that unifies the knowledge in the domain. Therefore, this paper proposes common database forensic investigation processes using a design science research approach. The proposed process comprises four phases, namely: 1) identification; 2) artefact collection; 3) artefact analysis; and 4) the documentation and presentation process. It allows the reconciliation of the concepts and terminologies of all common database forensic investigation processes; hence, it facilitates the sharing of knowledge on database forensic investigation among domain newcomers, users, and practitioners

Critically ill patients with diabetes and Middle East respiratory syndrome:a multi-center observational study

Background: Diabetes is a risk factor for infection with coronaviruses. This study describes the demographic, clinical data, and outcomes of critically ill patients with diabetes and Middle East Respiratory Syndrome (MERS).Methods: This retrospective cohort study was conducted at 14 hospitals in Saudi Arabia (September 2012–January 2018). We compared the demographic characteristics, underlying medical conditions, presenting symptoms andsigns, management and clinical course, and outcomes of critically ill patients with MERS who had diabetes compared to those with no diabetes. Multivariable logistic regression analysis was performed to determine ifdiabetes was an independent predictor of 90-day mortality.Results: Of the 350 critically ill patients with MERS, 171 (48.9%) had diabetes. Patients with diabetes were more likely to be older, and have comorbid conditions, compared to patients with no diabetes. They were more likely topresent with respiratory failure requiring intubation, vasopressors, and corticosteroids. The median time to clearance of MERS-CoV RNA was similar (23 days (Q1, Q3: 17, 36) in patients with diabetes and 21.0 days (Q1, Q3: 10, 33) in patients with no diabetes). Mortality at 90 days was higher in patients with diabetes (78.9% versus 54.7%, p <0.0001). Multivariable regression analysis showed that diabetes was an independent risk factor for 90-day mortality(odds ratio, 2.09; 95% confidence interval, 1.18–3.72).Conclusions: Half of the critically ill patients with MERS have diabetes; which is associated with more severe disease. Diabetes is an independent predictor of mortality among critically patients with MERS

Critically ill patients with diabetes and Middle East respiratory syndrome:a multi-center observational study

Background: Diabetes is a risk factor for infection with coronaviruses. This study describes the demographic, clinical data, and outcomes of critically ill patients with diabetes and Middle East Respiratory Syndrome (MERS).Methods: This retrospective cohort study was conducted at 14 hospitals in Saudi Arabia (September 2012–January 2018). We compared the demographic characteristics, underlying medical conditions, presenting symptoms andsigns, management and clinical course, and outcomes of critically ill patients with MERS who had diabetes compared to those with no diabetes. Multivariable logistic regression analysis was performed to determine ifdiabetes was an independent predictor of 90-day mortality.Results: Of the 350 critically ill patients with MERS, 171 (48.9%) had diabetes. Patients with diabetes were more likely to be older, and have comorbid conditions, compared to patients with no diabetes. They were more likely topresent with respiratory failure requiring intubation, vasopressors, and corticosteroids. The median time to clearance of MERS-CoV RNA was similar (23 days (Q1, Q3: 17, 36) in patients with diabetes and 21.0 days (Q1, Q3: 10, 33) in patients with no diabetes). Mortality at 90 days was higher in patients with diabetes (78.9% versus 54.7%, p <0.0001). Multivariable regression analysis showed that diabetes was an independent risk factor for 90-day mortality(odds ratio, 2.09; 95% confidence interval, 1.18–3.72).Conclusions: Half of the critically ill patients with MERS have diabetes; which is associated with more severe disease. Diabetes is an independent predictor of mortality among critically patients with MERS