The Biogeochemical Cycling of Particulate Trace Metals off the Southwest African and Peruvian Shelves

Marine particles in the ocean play an important role in the marine biogeochemical cycling of trace metals (TMs), yet our understanding of the marine biogeochemical cycling of TMs remains incomplete. Additionally, particulate TM (pTM) datasets from key dynamic regions of the global ocean, such as continental shelves, upwelling sites, and oxygen minimum zones (OMZs), are lacking, impeding progress toward fully understanding the processes which impact pTM cycling and distributions. This work studies the biogeochemical cycling of particulate iron (Fe), manganese (Mn), cobalt (Co), aluminum (Al), copper (Cu), nickel (Ni), zinc (Zn), cadmium (Cd), lead (Pb), titanium (Ti), vanadium (V), and phosphorus (P) on the SW African and Peruvian shelves, employing a chemical leach to marine particles collected on two separate research expeditions. The distributions and biogeochemical cycling of biogeochemical tracers, molybdenum (Mo), barium (Ba), chromium (Cr), tungsten (W), thorium (Th), and uranium (U) are explored only on the SW African shelf. Transects from these sites traversed through contrasting biogeochemical regimes with diverse particle sources, including the Benguela and Humboldt upwelling regions, OMZs, and the Congo River plume, offering unique gradients under which pTM cycling can be studied. Differentiating between labile and refractory pTM fractions, provided a more accurate assessment of the biogeochemical behavior and fate of pTMs within the different marine environments. Elemental ratios and particle type proxies were also utilized to determine redox and scavenging processes, and biological uptake of TMs in the water column. This approach allowed for the characterization of the principal carrier phases of pTMs in the water column, which is a critical step toward constraining the mechanisms that control their fate and interactions with dissolved phases in the water column

Cor triatriatum with persistent levoatrial cardinal vein late presented as severe mitral stenosis

AbstractCor triatriatum is a rare congenital cardiac anomaly that usually becomes symptomatic in the first years of life. We present a 28-year-old pregnant female patient presented with shortness of breath, palpitations and decreased exercise tolerance. Transthoracic (TTE) and transesophageal (TEE) echocardiography showed cor triatriatum, features of severe mitral stenosis and atrial septal defect (ASD). The patient underwent successful surgical correction with an uneventful postoperative course

Detection of Covid-19 and chest pneumonia based on X-ray images using Deep-Transfer Learning

لقي العديد من الأشخاص حتفهم نتيجة تفشي فيروس كورونا في عام 2019 (كوفيد-19)، والذي أثر أيضًا على ملايين آخرين في جميع أنحاء العالم. تنتشر العدوى بسرعة. ولذلك، فإن التكنولوجيا التي تتيح الكشف السريع عن الفيروسات ستوفر لمتخصصي الرعاية الصحية المساعدة التي هم في أمس الحاجة إليها. تهدف هذه الدراسة إلى التعرف على مرض كوفيد-19 من صور الأشعة السينية للأشخاص الأصحاء والمصابين بالالتهاب الرئوي باستخدام نموذج VGG16 المعدل. حقق النموذج المقترح نتائج أفضل من الدراسات السابقة المقدمة بدقة 99.13% واستدعاء 99% ودقة 98.70%.Numerous people have died as a result of the coronavirus outbreak in 2019 (COVID-19), which also affected millions of others worldwide. The infection spreads quickly. Therefore, technology that enables quick virus detection will offer healthcare professionals much-needed assistance. This study aims to identify COVID-19 disease from X-ray images of healthy and infected people with pneumonia by using a modified VGG16 model. The proposed model achieved better results than previous studies presented with an accuracy of 99.13%, a recall of 99%, and a precision of 98.70%

Phytochemical Analysis of Cultivated and Wild Salvia Palaestina using GC-MS: Acomparative study

The leaves of cultivated populations of Salvia palaestina (Lamiaceae) were collected from seven different governorates in Palestine to compare their phytochemical profiles to wild populations. Twenty volatile and semivolatile components were separated and identified by GC-MS. The major components in all the cultivated S. palaestina leaves were eucalyptol and camphor excluding one sample that was collected from Jericho. This sample revealed camphor as the predominant component (30.65%) while in the rest of the cultivated samples, camphor did not exceed 9.2% level. Moreover, thujone derivatives in Jericho's sample were abundant at high concentrations (28.9%) in comparison to other populations which did not exceed more than 2%. The wild S. palaestina leaves, showed eucalyptol as a major component in all samples from different locations with higher concentration than the cultivated leaves, while the later had a higher amount of camphor.We would like to thank the Central Public Health Laboratory CPHL staff, Ministry of Health in Ramallah for providing the GC-MS instrument for the analysis. Special thanks to Dr. Asad Ramlawi, Deputy Minister, Ministry of Health for his continuous support. Thanks are extended to Mr. Ibrahim Salem for facilitating this research at the Ministry of Health in Ramallah

One-pot pseudo five-component synthesis and antioxidant evaluation of 4,4'-(aryl-methylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)

A simple method for the synthesis of some 4,4'-(aryl-methylene)bis(3-methyl-1H-pyrazol-5-ol) derivatives via a one-pot pseudo five-component reaction of phenyl hydrazine, ethyl acetoacetate and aldehydes in acetic acid is reported. The prepared compounds were characterized by elemental analyses and spectral data. Some of the synthesized compounds were screened for their antioxidant activity using 2,2'-azino-bis(3-ethyl benzothiazoline-6-sulfonic acid (ABTS) method; all the investigated compounds showed similar and higher antioxidant activity than ascorbic acid and exhibited high protection against DNA damage induced by the bleomycin iron complex

Knowledge, Attitude and Practice toward COVID-19 among the Population attending primary healthcare centers in Makkah Al-Mukarramah Saudi Arabia 2022

Background: Since the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) as a pandemic, it has become a major challenging public health problem worldwide. This pandemic has affected all aspects of Population life in almost all nations and among all socioeconomic groups. Population of all types are facing an unprecedented crisis with the rapid spread of COVID-19 and severity of the disease in many infected individuals.  As such many healthcare systems have been overwhelmed and HCWs presented with work load . There is a potential shortage of physical resources, such as ventilators and intensive care unit beds, needed to care for surges of critically ill patients, however, additional medical supplies and beds will be of limited help unless there is an adequate medical workforce, as the Middle East respiratory syndrome coronavirus (MERS-CoV) continues to occur in small outbreaks in Saudi Arabia. Aim of the study: To assessment the Knowledge, Attitude and Practice toward COVID-19 among the Population attending primary healthcare centers in Makkah Al-Mukarramah Saudi Arabia 2022.Method: Cross sectional study, was conducted among Saudi Arabia population in primary health care center in Makkah Al-Mukarramah. The questionnaire collected socio-demographic characteristics, assessment of Knowledge, Attitude and Practice toward COVID-19 Our total participants were(200).Results: show the relation of participant to Attitude, knowledge, Practice score towards COVID-19 regarding the Attitude the most of participants high attitude were (78.0) heave a significant relation were P-value <0.001 and X2 187.240, regarding the knowledge the most of participants high knowledge were (61.0%)  P-value <0.001 and X2 70.360, the Practice the most of participants high Practice were (77.0%) a significant relation were P-value <0.001 and X2 174.040. Conclusion: Study participants from KSA, not adequate knowledge, positive attitude, and acceptable practices towards COVID-19 Knowledge. Electronic and social media should be effectively utilized to spread awareness of COVID-19 among the public, the Population worry levels regarding transmitting for COVID-19 during the early stage of the COVID-19 pandemic, and subsequent awareness campaigns that were conducted were associated with increased knowledge, adherence to protective hygienic practices and reduction of anxiety toward the COVID-19 pandemic

Review; Social Worker, Clinical Laboratory , Nurses And Midwife Working Together In Suspected Child Abuse Cases

Child abuse is recognized as a worldwide issue that has significant ramifications for the physical and psychological well-being of its victims. Healthcare providers, as described below, engage with children and their families at various stages of healthcare. It is imperative for all nurses to possess the ability to recognize children who are vulnerable to danger or abuse, and respond appropriately. Midwives, nurses, social workers, and clinical laboratory professionals all possessed expertise and encountered comparable difficulties when dealing with child abuse. The ratio of healthcare personnel to patients in health facilities hinders the delivery of high-quality care at a structural level. These findings have ramifications for enhancing child abuse policy/guidelines and clinical practice. Compulsory child abuse training is essential for midwifery, nursing, and medical students, as well as in ongoing education programs for more seasoned practitioners

Common variants in toll-like receptor family genes and risk of gastric cancer: a systematic review and meta-analysis

Background: An increasing number of studies have suggested the relationship between single-nucleotide polymorphisms (SNPs) in toll-like receptor (TLR) genes and gastric cancer (GC) susceptibility; however, the available evidence is contradictory. This meta-analysis aimed to comprehensively evaluate whether the SNPs within the TLR family are related to GC development.Methods: PubMed, Scopus, and China National Knowledge Infrastructure (CNKI) were systematically searched up to May 2023 to obtain the pertinent publications. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were applied to examine the associations using the random-effects model.Results: A total of 45 studies with 25,831 participants (cases: 11,308; controls: 14,523) examining the relation of 18 different SNPs in the TLR family to GC were analyzed. Variations in TLR-4 rs4986790, TLR-4 rs4986791, TLR-5 rs5744174, and TLR-9 rs187084 were significantly associated with increased risk of GC in different genetic models. No significant association was detected for TLR-2-196 to -174de (Delta22), TLR-2 rs3804100, TLR-4 rs11536889, TLR-4 rs11536878, TLR-4 rs2770150, TLR-4 rs10116253, TLR-4 rs1927911, TLR-4 rs10983755, TLR-4 rs10759932, TLR-4 rs1927914, and TLR-10 rs10004195.Conclusion: These findings indicate that variations in TLR-4, TLR-5, and TLR-9 genes were found to be potential risk factors for GC

The Effectiveness of Protected Areas in Conserving Globally Threatened Western Tragopan Tragopan melanocephalus.

Protected areas are a critical tool to conserve biodiversity in the face of the global crisis of species extinction. Here, we present the first ever management effectiveness assessment of Pakistan's Protected Areas (PAs). We link these assessments to the delivery of conservation outcomes focusing on the threatened Western Tragopan (Tragopan melanocephalus) endemic to Pakistan and India. We used two approaches, first mapping the spatial distribution of potential habitat coverage using machine learning ensemble models and second, an assessment of the management effectiveness of protected areas. Our results show that only Machiara National Park scored just above 40% (indicating relatively weak management), 22 of the PAs fell within the 25-50% quantile (indicating weak management), and 3 scored below 25% (indicating poor management). PAs within the species distributional range covered 92,387 ha which is only 2% of the total potential habitat of the Tragopan. Scoring of Planning element was insufficient both in term of the site and species. Likewise, inputs (e.g., research and monitoring program, staff numbers, staff training, current budget, security of budget, and management after process) were also inadequate. Finally, we recommend the establishment of more protected areas within the species potential habitat and inclusion of species-specific plans in Pakistan's PAs management

Periodic EEG Patterns in the Intensive Care Unit (ICU): Definition, Recognition and Clinical Significance

Periodic electroencephalographic (EEG) patterns are frequently recorded during ICU EEG monitoring in patients with altered mental status; these EEG features represent electrical discharges, ictal in appearance, occuring at regular intervals. They are known as lateralized periodic discharges (LPDs), bilateral independent periodic discharges (BIPDS), generalized periodic discharges (GPDs), continuous 2/s GPDs with triphasic morphology or triphasic waves (TWs) and Stimulus Induced Evolving Lateralized Rhytmic delta activity or Si-Evolving LRDA (previously SIRPIDS); other periodic, rhythmic patterns are Occasional frontally predominant brief 2/s GRDA (FIRDA previously), Lateralized rhythmic delta activity (LRDA) and Brief potentially ictal rhythmic discharges or B (I)RDs. The role of most (not all) of these EEG patterns is controversial; there is no consensus on which patterns are associated with ongoing seizure injury, which patterns need to be treated, and how aggressively they should be treated. Many authors consider these patterns as an unstable state on an ictal-interictal EEG continuum; the aim of the present chapter is to gain knowledge of these EEG features, show their association with known neurologic pathologies/syndromes and finally how to manage them