12 research outputs found
Evaluation of preparedness of healthcare student volunteers against Middle East respiratory syndrome coronavirus (MERS-CoV) in Makkah, Saudi Arabia : a cross-sectional study
Aim:
To assess the knowledge and attitude of senior medical, dental, nursing and pharmacy students toward Middle East respiratory syndrome-corona virus (MERS-CoV) in Saudi Arabia.
Subjects and methods:
A cross-sectional survey using a 21-item questionnaire was conducted for a 3-month period from November 2015–January 2016 in Makkah, Saudi Arabia. The questionnaire was designed to evaluate students’ understanding and perception of MERS-CoV. An ANOVA test was used to determine the association of study discipline and academic year with the student knowledge score on MERS.
Results:
A total of 364 students were assessed during the study. The majority (62%) of the participants were in the 20–22-year age group. More than half (53%) were pharmacy students followed by (22%) medical students. More than two thirds (71%) of the participants were aware that MERS is caused by the coronavirus. More than half (59%) of the participants believed that MERS can be transmitted through direct or indirect contact with infected camels. A statistically significant association was reported between the study discipline and mean knowledge score (p < 0.0001) with medical students achieving an overall better knowledge score compared with students from other study disciplines.
Conclusion:
Overall, students had good knowledge about MERS epidemiology, transmission and the recommended protective measures. However, students expressed their reluctance to work in healthcare facilities with inadequate MERS infection control isolation policies
Relative metabolic stability, but disrupted circadian cortisol secretion during the fasting month of Ramadan.
BACKGROUND: Chronic feeding and sleep schedule disturbances are stressors that exert damaging effects on the organism. Practicing Muslims in Saudi Arabia go through strict Ramadan fasting from dawn till sunset for one month yearly. Modern era Ramadan practices in Saudi Arabia are associated with disturbed feeding and sleep patterns, namely abstaining from food and water and increasing daytime sleep, and staying awake and receiving food and water till dawn. HYPOTHESIS: Strict Ramadan practices in Saudi Arabia may influence metabolism, sleep and circadian cortisol secretion. PROTOCOL: Young, male Ramadan practitioners were evaluated before and two weeks into the Ramadan. Blood samples were collected at 9.00 am and 9.00 pm for measurements of metabolic parameters and cortisol. Saliva was collected serially during the day for cortisol determinations. RESULTS: Ramadan practitioners had relative metabolic stability or changes expected by the pattern of feeding. However, the cortisol circadian rhythm was abolished and circulating insulin levels and HOMA index were increased during this period. DISCUSSION: The flattening of the cortisol rhythm is typical of conditions associated with chronic stress or endogenous hypercortisolism and associated with insulin resistance. CONCLUSIONS: Modern Ramadan practices in Saudi Arabia are associated with evening hypercortisolism and increased insulin resistance. These changes might contribute to the high prevalence of chronic stress-related conditions, such as central obesity, hypertension, metabolic syndrome and diabetes mellitus type 2, and their cardiovascular sequelae observed in the Kingdom
Correction: Relative Metabolic Stability, but Disrupted Circadian Cortisol Secretion during the Fasting Month of Ramadan.
[This corrects the article on p. e60917 in vol. 8.]
Relative Metabolic Stability, but Disrupted Circadian Cortisol Secretion during the Fasting Month of Ramadan
Background: Chronic feeding and sleep schedule disturbances are
stressors that exert damaging effects on the organism. Practicing
Muslims in Saudi Arabia go through strict Ramadan fasting from dawn till
sunset for one month yearly. Modern era Ramadan practices in Saudi
Arabia are associated with disturbed feeding and sleep patterns, namely
abstaining from food and water and increasing daytime sleep, and staying
awake and receiving food and water till dawn.
Hypothesis: Strict Ramadan practices in Saudi Arabia may influence
metabolism, sleep and circadian cortisol secretion.
Protocol: Young, male Ramadan practitioners were evaluated before and
two weeks into the Ramadan. Blood samples were collected at 9.00 am and
9.00 pm for measurements of metabolic parameters and cortisol. Saliva
was collected serially during the day for cortisol determinations.
Results: Ramadan practitioners had relative metabolic stability or
changes expected by the pattern of feeding. However, the cortisol
circadian rhythm was abolished and circulating insulin levels and HOMA
index were increased during this period.
Discussion: The flattening of the cortisol rhythm is typical of
conditions associated with chronic stress or endogenous hypercortisolism
and associated with insulin resistance.
Conclusions: Modern Ramadan practices in Saudi Arabia are associated
with evening hypercortisolism and increased insulin resistance. These
changes might contribute to the high prevalence of chronic
stress-related conditions, such as central obesity, hypertension,
metabolic syndrome and diabetes mellitus type 2, and their
cardiovascular sequelae observed in the Kingdom
Correction: Relative Metabolic Stability, but Disrupted Circadian Cortisol Secretion during the Fasting Month of Ramadan
Biochemical and endocrine parameters in the morning and evening samples collected on the two visits.
<p>Biochemical and endocrine parameters in the morning and evening samples collected on the two visits.</p
Demographic and anthropometric characteristics of the study group at the first visit.
<p>BP, Blood pressure.</p
Meal time and sleep patterns during the pre-fasting month of Shaaban and the fasting month of Ramadan.
<p>Meal time and sleep patterns during the pre-fasting month of Shaaban and the fasting month of Ramadan.</p