4 research outputs found
10-year institutional retrospective case series of decompressive craniectomy for malignant middle cerebral artery infarction (mMCAI)
Background:
A 10-year (2005β2015) retrospective case series of patients undergoing decompressive craniectomy for malignant middle cerebral artery infarction (mMCAI) was undertaken.
Methods:
Patient demographics, comorbidities, pre- and postoperative neurologic state, operative timescales, craniectomy dimensions, and Glasgow Outcome Scale scores were analyzed.
Results:
Overall 40 patients underwent a decompressive craniectomy for mMCAI with a 30-day mortality of 17.5% (n = 7). Seventeen patients (42.5%) were male, with a mean age of 43 years (range: 16β64 years). Patients who survived had a lower mean age of 41 years (range: 16β59 years) than those who did not of 50 years (range: 42β63 years). The modal ictal and preoperative Glasgow Coma Scale scores were 14 (range: 5β15) and 7 (range: 3β12), which corresponded to motor scores of 6 and 5, respectively. The mean time from ictus to admission to the Institute of Neurological Sciences (INS) was 23.5 hours (range: 0.5β66 hours) and from INS admission to decompression 7.5 hours (range: 0.5β46 hours). Approximately 60% of patients had an βearlyβ craniectomy (under 48 hours from ictus) and 60% of patients had a craniectomy performed less than 24 hours from INS admission. The mean maximum anteroposterior craniectomy diameter measured 13 cm (range: 10.93β15.12 cm) and the mean surface area was 92.68 cm2 (range: 76.14β124.42 cm2). Overall 80% of patients had a modal Glasgow Outcome Scale score of 3 (range: 2β5) at discharge, 3 months, 6 months, 9 months, and 12 months. The median length of stay was 3 days (range: 6 hours to 11 days) for nonsurvivors and 13 days (range: 1β365 days) for survivors.
Conclusion:
Decompressive craniectomy for mMCAI is suitable in selected patients, and the local practice is consistent with current evidence