Sick Building Syndrome in Apartment Buildings in Jordan

The present study was conducted to investigate the concept of sick building syndrome which has recently been receiving attention to improve the indoor environmental quality in housing projects in Jordan. Apartment buildings were selected in three locations in Jordan; Amman, Irbid and Zarqa to represent different climatic regions in Jordan. The methods of enquiries were based on observation(physical architectural and detailed analysis of the buildings),calculations of the environmental factors which affect indoor air quality and healthy environment and questionnaires designed and distributed to investigate occupants’ perception in terms of health and building conditions. The findings revealed that there were significant differences among geographical locations of apartment buildings in Jordan. Zarqa had the most severe condition because of the crowdness in the urban setting and the extreme weather conditions. Moreover, building physical configuration and attributes such as window sizes and types, envelope design, location of the apartment in the building, orientation and building layout had significant effects on the concept of the sick building syndrome

Financial Transfer and Its Impact on the Level of Democracy: A Pooled Cross-Sectional Time Series Model.

This dissertation is a pooled time series, cross-sectional, quantitative study of the impact of international financial transfer on the level of democracy. The study covers 174 developed and developing countries from 1976 through 1994. Through evaluating the democracy and democratization literature and other studies, the dissertation develops a theory and testable hypotheses about the impact of the international variables foreign aid and foreign direct investment on levels of democracy. This study sought to determine whether these two financial variables promote or nurture democracy and if so, how? A pooled time-series cross-sectional model is developed employing these two variables along with other relevant control variables. Control variables included the presence of the Cold War and existence of formal alliance with the United States, which account for the strategic dimension that might affect the financial transfer - level of democracy linkage. The model also includes an economic development variable (per capita Gross National Product) to account for the powerful impact for economic development on the level of democracy, as well as a control for each country's population size. By addressing and the inclusion of financial, economic, strategic, and population size effects, I consider whether change in these variables affect the level of democracy and in which direction. The dissertation tests this model by employing several techniques. The variables are subjected to bivariate and multivariate analysis including bivariate correlations, analysis of variance, and ordinary least square (OLS) multivariate regression with robust matrix and a lagged dependent variable. Panel corrected standard error (PCSE) was also employed to empirically test the pooled timeseries cross-sectional multivariate model. The dissertation analytical section concludes with path analysis testing which showed the impact of each of the independent variables on the dependent variable. The findings indicate less impact of international financial variables upon the level of democracy than hypothesized. Foreign assistance correlates negatively with economic development levels and has no effect on democracy levels. In contrast, foreign direct investment associates positively to economic development levels and, through increased economic development, contributes to democracy

Evaluating Indoor Air Quality (IAQ) as Modifying Factor in Designing Public School Buildings in Jordan

The most fundamental goal in the design of educational facilities is to provide an environment that encourages learning achievement for students and teachers. Poor indoor air quality (IAQ) can negatively affect student health, comfort and performance that will eventually produce unacceptable learning environment. Poor IAQ can decrease a person's ability to perform specific mental tasks requiring concentration, calculation and memory. Therefore, schools should be designed, built and maintained in away to minimize and control the source of pollution. Around 29% of Jordanians occupy school buildings each day. A specific prototype building design was applied in the different locations of the country. This prototype could be appropriate for one location but it is not for the entire country that has diversity in climatic and environmental conditions The purpose of this research paper was to evaluate the indoor air quality in public school buildings in urban and rural area, through investigations of the causes and its effects on student health, comfort, and performance. Achieving healthy indoor air quality is a multifaceted a problem which can be arrived at by a comprehensive and interdisciplinary approach to the design, construction and operation of the school building. Results indicate that the prototype system used was not appropriate as healthy school design, and it did not take into consideration the indoor environmental factors as crucial issue in designing school buildings

1,2,3-Triazole derivatives as highly selective cannabinoid receptor type 2 (CB2) agonists

The cannabinoid receptor 2 (CB2 receptor) has attracted considerable interest, mainly due to its potential as a target for therapeutics for treating various diseases that have a neuroinflammatory or neurodegenerative component while avoiding the adverse psychotropic effects that accompany CB1 receptor-based therapies. With the appreciation that CB2-selective ligands show marked functional selectivity, there is a renewed opportunity to explore this promising area of research from both a mechanistic as well as a therapeutic perspective. In this research, we are interested in the discovery of new chemotypes as highly selective CB2 modulators, which may serve as good starting points for further optimization towards the development of CB2 therapeutics. In search of new chemotypes as CB2 selective agents, we screened a series of triazole derivatives with interesting bioactive scaffolds, which led to the discovery of two novel and highly selective ligands for CB2 receptors. Compounds 6 and 11 produced a concentration-dependent inhibition of specific [3H]-CP55,940 (CB2) binding with Ki ± SEM values of 105.3 ± 22.6 and 116.4 ± 19.5 nM, respectively, while no binding affinity towards CB1 receptors or opioid receptors was observed. The CB2 functional activity of 6 and 11, as measured by a GPCR Tango assay (G-protein independent β-arrestin translocation assay), revealed that these compounds act as CB2 agonists with EC50 values ± SEM of 1.83 ± 0.16 and 1.14 ± 0.52 µM, respectively. Molecular modeling results showed that both compounds fit well into the active site of the CB2 receptor and showed strong hydrophobic interactions with key residues. In conclusion, the new triazole derivatives (6 and 11) showed promising activity towards CB2 receptors and have great potential to be developed into therapeutically useful CB2 agonists through hit-to-lead optimization

The Role of Media and Islamic Criminal Legislation in Reducing Crime (From the perspective of students of the University of Jordan)

The study aimed to know the role of the media and its various styles, as well as the role of Islamic criminal legislation in reducing crime and identifying the obstacles that limit the effectiveness of the media in the prevention of crime. A random sample of 600 students was selected at different university levels at the University of Jordan, as well as personal background factors (independent variables): sex, place of residence, specialty, so that eleven different positions were identified, asking the respondents to determine their opinion on their respective trends. Keywords: Role, Media, Islamic Criminal Legislation, Crime DOI: 10.7176/JPCR/44-05 Publication date: September 30th 201

Assessment of upper respiratory and gut bacterial microbiomes during COVID-19 infection in adults: potential aerodigestive transmission

\ua9 2025. The Author(s). SARS-CoV-2 is the viral pathogen responsible for COVID-19. Although morbidity and mortality frequently occur as a result of lung disease, the gastrointestinal (GI) tract is recognized as a primary location for SARS-CoV-2. Connections and interactions between the microbiome of the gut and respiratory system have been linked with viral infections via what has been referred to as the \u27gut-lung axis\u27 with potential aerodigestive communication in health and disease. This research explored the relationship between the microbiomes of the upper respiratory and GI tracts in patients with COVID-19 and examined Extraesophageal reflux (EOR), a mechanism which could contribute to dysregulated communication between the GI and respiratory tract (as identified in COVID-19). 97 patients with a laboratory diagnosis of COVID-19 infection, and 50 age-matched controls were recruited and stool, saliva and sputum were obtained from each participant. ELISA Pepsin tests and Reflux Symptom Index scores (RSI) were conducted for EOR assessment. DNA sequencing of the V4 region of the 16 S rRNA gene was performed for microbiome analysis. No differences were observed between the fecal microbiome\u27s alpha and Shannon diversity indices; however, a distinct microbial composition was observed in COVID-19 patients (when compared to the controls). The respiratory microbiota from individuals with COVID-19 demonstrated a statistically significant reduction in Shannon diversity and bacterial richness alongside an overall reduction in the prevalence of organisms from a typical healthy respiratory microbiome. Furthermore, the bacterial richness of the stool and sputum samples was significantly lower among COVID-19 patients admitted to ICU. A significantly higher RSI score and salivary pepsin level were detected among those with COVID-19. The data indicates that COVID-19 is associated with a dysregulation of both the gut and lung microbiome with a more marked perturbation in the lung, particularly among COVID-19 patients who had been admitted to the ICU. The presence of increased RSI scores, combined with elevated levels of Pepsin, suggests that increased micro-aspiration may occur, which is consistent with of under-recognized interactions between the GI and lung microbiomes in COVID-19 patients and requires additional study. Such studies would benefit from the insights provided by biological samples which reflect the continuum of the aerodigestive tract

Trapezoidal Scheme for the Numerical Solution of Fractional Initial Value Problems

The purpose of this study is to recall the main concepts and definitions in relation to the fractional calculus. In light of this overview, we will propose a novel fractional version of the so-called Trapezoid method named by the fractional Trapezoid method. Such a method will then be used to numerically solve the analog version of the initial value problems called fractional initial value problem FIVPs. As consequences of the proposed numerical approach, several numerical examples will be illustrated to verify the efficiency of the proposed numerical approach

Techniques for Arbuscular Mycorrhiza Inoculum Reduction

It is well established that arbuscular mycorrhizal (AM) fungi can play a significant role in sustainable crop production and environmental conservation. With the increasing awareness of the ecological significance of mycorrhizas and their diversity, research needs to be directed away from simple records of their occurrence or casual speculation of their function (Smith and Read 1997). Rather, the need is for empirical studies and investigations of the quantitative aspects of the distribution of different types and their contribution to the function of ecosystems. There is no such thing as a fungal effect or a plant effect, but there is an interaction between both symbionts. This results from the AM fungi and plant community size and structure, soil and climatic conditions, and the interplay between all these factors (Kahiluoto et al. 2000). Consequently, it is readily understood that it is the problems associated with methodology that limit our understanding of the functioning and effects of AM fungi within field communities. Given the ubiquous presence of AM fungi, a major constraint to the evaluation of the activity of AM colonisation has been the need to account for the indigenous soil native inoculum. This has to be controlled (i.e. reduced or eliminated) if we are to obtain a true control treatment for analysis of arbuscular mycorrhizas in natural substrates. There are various procedures possible for achieving such an objective, and the purpose of this chapter is to provide details of a number of techniques and present some evaluation of their advantages and disadvantages. Although there have been a large number of experiments to investigated the effectiveness of different sterilization procedures for reducing pathogenic soil fungi, little information is available on their impact on beneficial organisms such as AM fungi. Furthermore, some of the techniques have been shown to affect physical and chemical soil characteristics as well as eliminate soil microorganisms that can interfere with the development of mycorrhizas, and this creates difficulties in the interpretation of results simply in terms of possible mycorrhizal activity. An important subject is the differentiation of methods that involve sterilization from those focussed on indigenous inoculum reduction. Soil sterilization aims to destroy or eliminate microbial cells while maintaining the existing chemical and physical characteristics of the soil (Wolf and Skipper 1994). Consequently, it is often used for experiments focussed on specific AM fungi, or to establish a negative control in some other types of study. In contrast, the purpose of inoculum reduction techniques is to create a perturbation that will interfere with mycorrhizal formation, although not necessarily eliminating any component group within the inoculum. Such an approach allows the establishment of different degrees of mycorrhizal formation between treatments and the study of relative effects. Frequently the basic techniques used to achieve complete sterilization or just an inoculum reduction may be similar but the desired outcome is accomplished by adjustments of the dosage or intensity of the treatment. The ultimate choice of methodology for establishing an adequate non-mycorrhizal control depends on the design of the particular experiments, the facilities available and the amount of soil requiring treatment

Enhanced Efficacy of Some Antibiotics in the Presence of Silver Nanoparticles Against Clinical Isolate of <em>Pseudomonas aeruginosa</em> Recovered from Cystic Fibrosis Patients

\ua9 2024 Al-Momani et al. Introduction: Given the increasing frequency of drug-resistant bacteria and the limited progress in developing new antibiotics, it is necessary to explore new methods of combating microbial infections. Nanoparticles, particularly silver nanoparticles (Ag-NPs), have shown exceptional antibacterial characteristics; however, elevated concentrations of Ag-NPs can produce noticeable levels of toxicity in mammalian cells. Aim: This study examined the potential synergistic effect of combining a low dosage of Ag-NPs and anti-pseudomonas drugs against Pseudomonas aeruginosa (ATCC strain) and eleven clinical isolates from cystic fibrosis patients. Methods: The Ag-NPs were chemically produced by utilizing a seed extract from Peganum Harmala and characterized via ultraviolet-visible spectroscopy and scanning electron microscopy. The broth microdilution technique was utilized to investigate the minimum inhibitory concentration (MIC) of Ag-NPs and eight antibiotics (Piperacillin, Ciprofloxacin, Levofloxacin, Meropenem, Amikacin, Ceftazidime, Gentamicin, Aztreonam). The fractional inhibitory concentration index (FICI) was determined via the checkerboard method to evaluate the synergistic effects of Ag-NPs and various antibiotics. Results: The biosynthesized Ag-NPs were uniformly spherical and measured around 15 nm in size. When combined with antibiotics, Ag-NP produced statistically significant reductions in the amount of antibiotics required to completely prevent P. aeruginosa growth for all strains. The findings revealed that the MIC of Ag-NPs was 15 ug/mL for all strains which decreased substantially when administered with antibiotics at a dose of 1.875–7.5 ug/mL. The majority of Ag-NP and antibiotic combinations exhibited a synergistic or partially synergistic impact. This was particularly noticeable in combinations containing Meropenem, Ciprofloxacin, and Aztreonam (in which the FIC index was less than or equal to 0.5). Conclusion: The findings revealed that combining Ag-NPs with antibiotics was more effective than using Ag-NPs or antibiotics in isolation and that combinations of Ag-NPs and antimicrobial agents displayed synergistic activity against the majority of strains assessed

Proposed Vision for Enhancing Psychological Capital Management as a Gateway to Achieving Competitive Advantage in Arab Universities

This paper develops proposed vision for enhancing psychological capital management as a gateway to achieving competitive advantage in Arab universities. The descriptive approach and prospective analysis approach are used to achieve the research objectives. The questionnaire is used as a research instrument. The research sample consists of (513) faculty members randomly selected and 199 experts selected using the stratified purposeful sampling method. The findings indicate that the overall mean of the reality of availability of psychological capital is (3.49) with a medium degree for all dimensions, as the highest dimension is resilience with (3.56) while the lowest dimension is hope with (3.43). The results also show there is a consensus among experts on the mechanisms for enhancing the management of psychological capital in Arab universities, as all dimensions achieve a high degree, as follows: hope (4.94), self-efficacy (4.87), self-resilience (4.86), and optimism (4.85). Given these results, the research develops a vision to enhance the management of psychological capital in Arab universities as a gateway to achieving competitive advantage including its objectives, starting points, elements, implementation requirements, implementation stages, those responsible for implementing the proposed vision, and obstacles to its implementation and methods to overcome