生理濃度の糖質コルチコイドは病的なDNA二重鎖切断を引き起こす

付記する学位プログラム名: 充実した健康長寿社会を築く総合医療開発リーダー育成プログラム京都大学新制・課程博士博士(医学)甲第24521号医博第4963号新制||医||1065(附属図書館)京都大学大学院医学研究科医学専攻(主査)教授 斎藤 通紀, 教授 萩原 正敏, 教授 戸井 雅和学位規則第4条第1項該当Doctor of Medical ScienceKyoto UniversityDFA

Organic sack garden ensuring nutrition and improve the food security on small scale households

An experiment was conducted in Gazipur district of Bangladesh in 2009 to study the effect of sack/bag gardening method for the first time in Bangladesh and to observe the suitability and opportunities of the method in context of Bangladesh that one of the most vulnarable country in the world with recent climate change. The peoples who are disadvangatage and living in unfavaourable ecosystems can able to grow and cook their own vegetables and have more diversiy in their diet by growing high nutritional products. The overall objective is to improve peoples ability to be food secure and more specifically are to increase the household food consumption and production also to increase their income through these activities. From the study it was observed that the vegetable production by sack gardenining method was a effective technology and received a attention from the household communities. It was also obsearved that the households consumption pattarn has changed in some extent with practicing the technology

Changes in Consumer Purchasing Behavior Due to COVID- 19 Pandemic

Due to the COVID-19 pandemic, the world is facing historical challenges without prior preparation. Because of the unavoidable economic crisis for the shutdown of numerous trade and industrial activities the COVID-19 pandemic has triggered substantial modifications in the habits of consumers all over the world. The pandemic has led to key changes in consumers purchasing and consumption behavior as the result of lockdown, social distancing, and uncertainty about the future due to its infectious nature. This study investigated the impact of the pandemic outbreak on consumers’ purchasing and consumption behavior in a developing country such as Bangladesh. An online survey was conducted for collecting data about the changes in buying behavior through a structured questionnaire. The research targeted 200 respondents belonging to different age-gender segments, qualifications & occupations, and household monthly income. The 191 completed responses had received and analyzed among 200 distributed structured questionnaires. The Partial Least Squares (PLS-SEM) method was applied, with the Smart PLS software v.3.3.2 for analyzing the proposed theoretical model and to test the developed hypotheses. The outcomes of the research strongly indicate that the health and safety concern, imposed restrictions, financial condition, surrounding environment-people, and other realities caused a remarkable change in consumer buying behavior. The outcomes of this study provide significant guidance to policy interventions, marketing decisions, and strategies for doing business as usual during and after the pandemic and perhaps add to the understanding of this unprecedented and ongoing phenomenon. Keywords: COVID-19 pandemic, consumer behavior, TPB model, panic buying, online shopping, risks perception. DOI: 10.7176/JMCR/77-04 Publication date:March 31st 202

Estimation of maternal serum albumin at term to determine its correlation with birth weight of babies

Background: Serum albumin is a vital laboratory indicator of nutrition status. Fetal weight depends upon the nutritional status of mothers. Indeed, the serum albumin status at term may help to assume the fetal weight. We do have not enough research-based data regarding this issue. The aim of this study was to estimate maternal serum albumin at term and to observe its correlation with the birth weight of babies. Methods: This cross-sectional analytical study was done at department of gynaecology and obstetrics, Sir Salimullah medical college and Mitford hospital, Dhaka, Bangladesh from July 2019 to June 2020. A total of 96 mother-baby pairs were selected using purposive sampling method. Women with single full-term pregnancy based on fundal height on Naegele’s rule irrespective of any mode of delivery was included in this study. Mothers with normal albumin levels (3.6-5.2 gm/dl) were defined as group A and mothers with low albumin levels (<3.6 gm/dl) in group B. Statistical analyses of the results were obtained by using window-based computer software devised with SPSS-22. Results: In analyzing the maternal serum albumin level, we observed that majority of the participants were with normal albumin levels which were 81% and the rest 19% of patients were low albumin levels. In this study, it was observed that more than half (56.4%) of babies were male in group A and 9 (50.0%) in group B. The majority (94.9%) of babies’ birth weights were ≥2.5 kg in group A and 4 (22.0%) in group B. The difference of birth weight was statistically significant (p<0.05) between the two groups. Maternal serum albumin was significantly associated with birth weight of babies in multivariate analysis. But negatively correlated with newborn birth weight which is statistically significant.    Conclusions: Maternal albumin was observed to be directly proportional to the birth weight of babies

The association of serum C-reactive protein albumin ratio with polycystic ovarian syndrome

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder among women, characterized by various symptoms and long-term risks. Reliable diagnostic methods are needed to predict and diagnose PCOS. This study aimed to assess the serum C reactive protein/albumin ratio as a potential predictor and diagnostic tool for PCOS. Methods: This cross-sectional analytical study was conducted at the department of obstetrics and gynecology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, from September 2018 to August 2019. The study included 80 participants aged 18 to 45 years, with 40 healthy subjects in group I and 40 diagnosed cases of PCOS in group II. Serum C-reactive protein and serum albumin levels were measured, and data were analyzed using descriptive statistics and Unpaired t-tests. Results: The study group had a mean age of 23.98±2.61, while the comparison group had a mean age of 23.85±2.79. Serum CRP levels were significantly higher in newly diagnosed PCOS cases (5.73±3.35) compared to non-PCOS cases (2.89±0.85) (p<0.001). The study group had a significantly higher mean CRP: albumin ratio (0.123±0.07) compared to the comparison group (0.067±0.02) (p<0.001). Conclusions: This study found that serum CRP and the CRP/albumin ratio were increased in PCOS subjects, while serum albumin levels did not differ significantly from non-PCOS subjects. These findings suggest that the serum CRP/albumin ratio could be a potential marker for predicting and diagnosing PCOS

Correlation between single pre delivery symphysis-fundal height beyond 36 weeks of gestation and birth weight of newborn after delivery

Background: Accurate assessment of fetal weight is important for optimal obstetric management of labouring mothers. Among the methods of fetal weight estimation, symphysis-fundal height (SFH) measurement is inexpensive and non-invasive readily available simple and acceptable procedure of fetal weight estimation. On the other hand, high rate of low birth weight is one of the causes of high perinatal mortality in our country. Objective was to assess fetal birth weight by measuring symphysis-fundal height.Methods: This cross-sectional observational study was conducted in the department of obstetrics and gynaecology, Dhaka Medical College Hospital, Dhaka from July 2017 to June 2018. Total 200 consecutive pregnant women of gestational age more than 36 weeks were selected as per inclusion and exclusion criteria. The fetal birth weight was measured before delivery of the foetus by measuring SFH and using the formula and was compared with actual birth weight.Results: Maximum (35.5%) pregnant mother were in age group 21-25 years followed by 29.5% in 26-30 years, 25.5% in 31-35 years and 9.5% in >35 years age group and mean age was 28.27±4.95 years. Mean weight of new born was 2.81±0.61 kg. Mean symphysis-fundal height 32.76±3.73 cm and maximum (48.5%) pregnant mother had SFH in 35-36 cm group, followed by 30.5% had ≤30 cm and 21.0% had 31-34 cm in this study. New born birth weight had significant positive correlation with symphysis-fundal height.Conclusions: Symphysis-fundal height has significant positive correlation with birth weight of new born

Farming Systems for Improved Nutrition: a Formative Study

International literature accords immense importance to agriculture interventions in order to achieve better health and nutrition. It stresses the importance of women’s engagement, diversified production and consumption, and incorporation of other health and nutrition services into the agriculture extension services. Little is understood how communities perceive these dimensions in building their farming systems for better nutrition, particularly in the context of Bangladesh. This paper To understand the perceptions and needs of local farming communities in promoting agriculture for nutrition and how to address their needs, given the existing programmatic framework of a NGO, BRAC in Bangladesh. The research concludes that pilot testing of interventions based on the feedback received from the communities who have been exposed to the principles and experiences of nutrition-sensitive agriculture models is worth considering in defining a feasible model to promote agriculture for better nutrition.DFIDUKAI

Forest-based Tourism in Bangladesh: Status, Problems and Prospects

Bangladesh is a land of diverse forest-based natural attractions throughout the evergreen, semi-evergreen, and mangrove forest ecosystems. The article attempts at exploring various dimensions of ecotourism industry and critically analyzes the relationship among the stakeholders, overall strength-weakness of ecotourism sector and impediments hindering its development. National Parks, Ecoparks, Wildlife Sanctuaries, Game Reserves, and the like have been developed in the natural forest ecosystems to attract tourists from home and abroad. Cheap transportation, lodging and associated costs, unique scenic beauty and wilderness of all sites and socio-cultural diversity of indigenous communities living in the forest together make up the strength of the industry as a whole. The study identifies a number of impediments, including conflict among the stakeholders and forest degradation hindering expansion of ecotourism industry. For sustainable development of forest-based tourism, traditional ‘Top-down’ management approach is suggested to avoid and voice of all stakeholders needs to be considered in decision-making

Forest-based Tourism in Bangladesh: Status, Problems and Prospects

Bangladesh is a land of diverse forest-based natural attractions throughout the evergreen, semi-evergreen, and mangrove forest ecosystems. The article attempts at exploring various dimensions of ecotourism industry and critically analyzes the relationship among the stakeholders, overall strength-weakness of ecotourism sector and impediments hindering its development. National Parks, Ecoparks, Wildlife Sanctuaries, Game Reserves, and the like have been developed in the natural forest ecosystems to attract tourists from home and abroad. Cheap transportation, lodging and associated costs, unique scenic beauty and wilderness of all sites and socio-cultural diversity of indigenous communities living in the forest together make up the strength of the industry as a whole. The study identifies a number of impediments, including conflict among the stakeholders and forest degradation hindering expansion of ecotourism industry. For sustainable development of forest-based tourism, traditional ‘Top-down’ management approach is suggested to avoid and voice of all stakeholders needs to be considered in decision-making