Dysfunctional sleep-related cognition and anxiety mediate the relationship between multidimensional perfectionism and insomnia symptoms

Perfectionism is one of several personality traits associated with insomnia. Whilst research has examined the relationships between perfectionism and insomnia, the mediating role of dysfunctional sleep-related cognition (i.e. sleep-related worry and dysfunctional beliefs about the biological attribution of and consequences of poor sleep) has yet to be examined. This study aimed to determine whether aspects of multidimensional perfectionism were related to increased reporting of insomnia symptoms. In addition, the potential mediating role of dysfunctional sleep-related cognition and anxiety symptoms was examined. Members of the general population (N = 624) completed the Dysfunctional Beliefs and Attitudes About Sleep Scale, the Insomnia Severity Index, the Hospital Anxiety and Depression Scale, and the Multidimensional Perfectionism Scale. The results showed that perfectionism dimensions, anxiety symptoms, and dysfunctional sleep-related cognition were significantly associated with insomnia symptoms. Regression-based mediation analyses further showed that both dysfunctional sleep-related cognition and anxiety significantly mediated the associations between insomnia symptoms and three perfectionism dimensions (i.e. doubts about action, parental expectations, and parental criticism). The experience of perfectionistic tendencies, anxiety, and dysfunctional sleep-related cognition may initiate behavioural strategies (e.g. daytime napping) when faced with an acute sleep problem. However, these strategies may serve to transition insomnia from an acute to a chronic condition

GRIDCC: Real-time workflow system

The Grid is a concept which allows the sharing of resources between distributed communities, allowing each to progress towards potentially different goals. As adoption of the Grid increases so are the activities that people wish to conduct through it. The GRIDCC project is a European Union funded project addressing the issues of integrating instruments into the Grid. This increases the requirement of workflows and Quality of Service upon these workflows as many of these instruments have real-time requirements. In this paper we present the workflow management service within the GRIDCC project which is tasked with optimising the workflows and ensuring that they meet the pre-defined QoS requirements specified upon them

From Cavity Electromechanics to Cavity Optomechanics

We present an overview of experimental work to embed high-Q mesoscopic mechanical oscillators in microwave and optical cavities. Based upon recent progress, the prospect for a broad field of "cavity quantum mechanics" is very real. These systems introduce mesoscopic mechanical oscillators as a new quantum resource and also inherently couple their motion to photons throughout the electromagnetic spectrum.Comment: 8 pages, 6 figures, ICAP proceedings submissio

Single-photon optomechanics in the strong coupling regime

We give a theoretical description of a coherently driven opto-mechanical system with a single added photon. The photon source is modeled as a cavity which initially contains one photon and which is irreversibly coupled to the opto-mechanical system. We show that the probability for the additional photon to be emitted by the opto-mechanical cavity will exhibit oscillations under a Lorentzian envelope, when the driven interaction with the mechanical resonator is strong enough. Our scheme provides a feasible route towards quantum state transfer between optical photons and micromechanical resonators.Comment: 14 pages, 6 figure

Functional positional eye and eyelid movements

BACKGROUND: Positional manoeuvres are an important part of the neurological examination, particularly in patients with vertigo where the presence and characteristics of provoked nystagmus can help differentiate central from peripheral neurological disorders. METHODS: Case series of functional positional eye and eyelid movements. RESULTS: We report four patients with functional eye and eyelid movements provoked during positional manoeuvres. The range of abnormalities observed included positional convergence spasm, brief functional saccadic oscillations, and excessive positional blinking mimicking upbeat nystagmus. The functional movements described were present on a background of pre-existing peripheral or central nystagmus, or positional vertigo. CONCLUSION: Functional positional eye and eyelid movements may co-exist with organic nystagmus that renders an accurate interpretation of the manoeuvre more challenging. A thorough understanding of the clinical features that differentiate these two categories of eye/eyelid movements makes the analysis easier, thus preventing misdiagnosis and avoiding unnecessary investigations

A Case of Appendiceal Adenocarcinoma with Clinical Benefit from FOLFOX and Bevacizumab

A 44-year-old woman presented with lower abdominal pain and bilateral ovarian masses on ultrasound. Exploratory laparotomy revealed extensive peritoneal and intra-abdominal disease and an abnormal appendix. Bilateral salpingo-oophorectomy, infracolic omentectomy, ileocolic resection and primary anastomosis were performed. Final pathology revealed a primary appendiceal adenocarcinoma, poorly differentiated, of signet ring cell type. CT scan postoperatively revealed gross residual disease. The patient was treated with FOLFOX chemotherapy combined with bevacizumab. Repeat CT scan showed a decrease in residual disease and the patient clinically improved. After her treatment has been continued for 13 months, she remains clinically well and her CT scan shows sustained disease stability. Disseminated appendiceal carcinoma is generally considered to be refractory to 5-FU-based chemotherapy and, to our knowledge, this is the first reported case of a patient with appendiceal adenocarcinoma demonstrating clinical benefit and sustained stability of disease with combination chemotherapy plus bevacizumab

Identifikasi Miskonsepsi Siswa Kelas XI IPA 1 di SMA Negeri 3 Gorontalo Utara pada Konsep Larutan Penyangga

Penelitian ini merupakan penelitian deskriptif, yang bertujuan untuk mengidentifikasi miskonsepsi siswa terhadap konsep larutan penyangga. Penelitian ini dilakukan pada siswa kelas XI IPA 1 di SMA Negeri 3 Gorontalo Utara menggunakan tes piihan ganda (multiple choice) dengan alasan terbuka. Instrumen ini dapat membedakan antara siswa yang tahu konsep, tidak tahu konsep dan miskonsepsi. Pengamblan sampel dilakukan dengan cara sampling jenuh. Hasil penelitian secara keseluruhan menunjukkan bahwa miskonsepsi siswa kelas XI IPA 1 di SMA Negeri 3 Gorontalo Utara pada konsep larutan penyangga berada pada kategori tinggi yaitu nilai rata-rata sebesar 44,17%, tahu konsep nilai rata-rata 10,8%, tahu konsep tetapi kurang yakin nilai rata-rata 2,13% dan tidak tahu konsep nilai rata-rata sebesar 42,9%

Quantum interference in optical fields and atomic radiation

We discuss the connection between quantum interference effects in optical beams and radiation fields emitted from atomic systems. We illustrate this connection by a study of the first- and second-order correlation functions of optical fields and atomic dipole moments. We explore the role of correlations between the emitting systems and present examples of practical methods to implement two systems with non-orthogonal dipole moments. We also derive general conditions for quantum interference in a two-atom system and for a control of spontaneous emission. The relation between population trapping and dark states is also discussed. Moreover, we present quantum dressed-atom models of cancellation of spontaneous emission, amplification on dark transitions, fluorescence quenching and coherent population trapping.Comment: To be published in Journal of Modern Optics Special Issue on Quantum Interferenc