Model of demand for labor in the urfo pharmaceutical market

The purpose of the study is to comprehensive assessment of the structure of demand for labor in the pharmaceutical market of the URFO to build empirical functions of the demand for labor resources for pharmaceutical specialists with different qualifications.Цель исследования – комплексная оценка структуры спроса на труд на фармацевтическом рынке УрФО для построения эмпирических функций спроса на трудовые ресурсы для фармацевтических специалистов с разной квалификацией

CP Studies and Non-Standard Higgs Physics

There are many possibilities for new physics beyond the Standard Model that feature non-standard Higgs sectors. These may introduce new sources of CP violation, and there may be mixing between multiple Higgs bosons or other new scalar bosons. Alternatively, the Higgs may be a composite state, or there may even be no Higgs at all. These non-standard Higgs scenarios have important implications for collider physics as well as for cosmology, and understanding their phenomenology is essential for a full comprehension of electroweak symmetry breaking. This report discusses the most relevant theories which go beyond the Standard Model and its minimal, CP-conserving supersymmetric extension: two-Higgs-doublet models and minimal supersymmetric models with CP violation, supersymmetric models with an extra singlet, models with extra gauge groups or Higgs triplets, Little Higgs models, models in extra dimensions, and models with technicolour or other new strong dynamics. For each of these scenarios, this report presents an introduction to the phenomenology, followed by contributions on more detailed theoretical aspects and studies of possible experimental signatures at the LHC and other colliders.Comment: Report of the CPNSH workshop, May 2004 - Dec 2005, 542 pages. The complete report as well as its individual chapters are also available from http://kraml.home.cern.ch/kraml/cpnsh/report.htm

Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury

© Copyright © 2019 Akhmetzyanova, Kletenkov, Mukhamedshina and Rizvanov. Microglial cells, which are highly plastic, immediately respond to any change in the microenvironment by becoming activated and shifting the phenotype toward neurotoxicity or neuroprotection. The polarization of microglia/macrophages after spinal cord injury (SCI) seems to be a dynamic process and can change depending on the microenvironment, stage, course, and severity of the posttraumatic process. Effective methods to modulate microglia toward a neuroprotective phenotype in order to stimulate neuroregeneration are actively sought for. In this context, available approaches that can selectively impact the polarization of microglia/macrophages regulate synthesis of trophic factors and cytokines/chemokines in them, and their phagocytic function and effects on the course and outcome of SCI are discussed in this review

Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury

© Copyright © 2019 Akhmetzyanova, Kletenkov, Mukhamedshina and Rizvanov. Microglial cells, which are highly plastic, immediately respond to any change in the microenvironment by becoming activated and shifting the phenotype toward neurotoxicity or neuroprotection. The polarization of microglia/macrophages after spinal cord injury (SCI) seems to be a dynamic process and can change depending on the microenvironment, stage, course, and severity of the posttraumatic process. Effective methods to modulate microglia toward a neuroprotective phenotype in order to stimulate neuroregeneration are actively sought for. In this context, available approaches that can selectively impact the polarization of microglia/macrophages regulate synthesis of trophic factors and cytokines/chemokines in them, and their phagocytic function and effects on the course and outcome of SCI are discussed in this review

О свойстве неотслеживаемости нескольких схем подписи вслепую на основе уравнения Эль-Гамаля

Blind signature schemes are the essential element of many e-cash and e-voting systems. Anonymity in such systems is ensured through the blindness property of the signature schemes. We discuss the blindness property and analyze several ElGamal-type blind signature schemes regarding this property. We present effective attacks violating blindness on three schemes

EXPERIENCE IN THE EXPLOITATION OF ALUMINUM-CHROMIUM CATALYSTS IN THE PROCESS OF DEHYDROGENATION OF 2-METHYLBUTANE

В статье приводятся результаты исследования изменения характеристик алюмохромового катализатора дегидрирования парафиновых углеводородов ИМ-2201С. На примере промышленного процесса дегидрирования 2-метилбутана показано изменение каталитических свойств за 12 лет эксплуатации катализатора. Приводятся рекомендации по снижению расходных норм сырья.In the article results of research of change of characteristics of an alumina chromium catalyst of dehydrogenation of paraffinic hydrocarbons of mark IM-2201С are resulted. The industrial process of dehydrogenation of 2-methylbutane shows the change in catalytic properties over 12 years of operation of the catalyst. Recommendations are given to reduce the consumption rates of raw materials

FEATURES OF OPERATION OF POLYSTYRENE MEMBRANES IN PETROCHEMICAL INDUSTRY

В статье приводятся результаты исследования ионообменных мембран на основе полистирола. Описан процесс набухания ионообменной мембраны на примере набухания катионита в бутаноле. На примере высокосшитого катионита показан предел набухания исходного катионита (до формования мембраны). Установлена специфика набухания конечной мембраны после армирования.The article presents the research results of ion-exchange membranes based on polystyrene. Describes the process of swelling of ion exchange membrane for example, the swelling of the cation exchange resin in butanol. For example vysokochetkogo of the cation is shown to limit swelling, the source of cation (up to molding of the membrane). Specific features of swelling of the final membrane after reinforcement

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Cytotoxic CD8+ T Lymphocytes (CTL) efficiently control acute virus infections but can become exhausted when a chronic infection develops. Signaling of the inhibitory receptor PD-1 is an important mechanism for the development of virus-specific CD8+ T cell dysfunction. However, it has recently been shown that during the initial phase of infection virus-specific CD8+ T cells express high levels of PD-1, but are fully competent in producing cytokines and killing virus-infected target cells. To better understand the role of the PD-1 signaling pathway in CD8+ T cell cytotoxicity during acute viral infections we analyzed the expression of the ligand on retrovirus-infected cells targeted by CTLs. We observed increased levels of PD-L1 expression after infection of cells with the murine Friend retrovirus (FV) or with HIV. In FV infected mice, virus-specific CTLs efficiently eliminated infected target cells that expressed low levels of PD-L1 or that were deficient for PD-L1 but the population of PD-L1high cells escaped elimination and formed a reservoir for chronic FV replication. Infected cells with high PD-L1 expression mediated a negative feedback on CD8+ T cells and inhibited their expansion and cytotoxic functions. These findings provide evidence for a novel immune escape mechanism during acute retroviral infection based on PD-L1 expression levels on virus infected target cells