Effects of Er:YAG Laser Irradiation and Topical Fluoride Application on Inhibition of Enamel Demineralization

Objective:The aim of this study was to evaluate the effect of the Er:YAG laser and acidulated phosphate fluoride application on enamel solubility around orthodontic brackets via atomic absorption spectrometry.Materials and Methods:Twenty freshly extracted upper premolar teeth were divided into 2 halves. Each half was covered with a nail varnish, excluding 1 mm (width) of space around each side of the bracket base. Orthodontic brackets were bonded in the center of the isolated area. Four groups were generated. The first group was the control group, and no treatment was performed. In group II (F), only fluoride was applied. Groups III and IV were laser and fluoride combination groups. In Group III (LF), fluoride was applied to the laser-irradiated surface, whereas laser irradiation was performed on the fluoridated enamel surface in Group IV (FL group). Afterwards, samples were demineralized in an acidic solution for 96 hours, and calcium assessment was performed using atomic absorption spectrometry. Comparisons of the calcium ion release values of the groups were performed with Kruskal-Wallis and Tukey honestly significant difference post hoc tests. The statistical significance level was set at p < 0.05.Results:The least amount of calcium release was observed in the LF group (median, 112.7 ppm), while the parameter of the control group was the highest (median, 217.9 ppm). The differences between the control and F groups, control and LF groups, and LF and FL groups were statistically significant. No difference was recorded between the control and FL groups.Conclusion:Laser treatment followed by topical application of acidulated phosphate fluoride gel resulted in the lowest calcium dissolution from the enamel surface

Design and Implementation of an Interactive Interface for Demand Response and Home Energy Management Applications

Demand response (DR) implementations have recently found wide application areas in the context of smart grids. The effectiveness of these implementations is primarily based on the willingness of end-users to be involved in such programs. In this paper, an interactive and user-friendly interface is presented in order to facilitate and accordingly to increase the participation of end-users in DR programs. The proposed interface has the capability of providing the targeted information about the DR events to end-users and system operators, as well as allowing end-users to interactively monitor and control the progress of their appliances. In addition to its benefits to system operators and thus to the improved operation of power systems, the proposed interface particularly aims to exploit the potential energy-related cost savings by providing the required information and resources to end-users via mobile phone. A separate interface apart from the mentioned end-user oriented interface has also been developed for the system operator to more effectively check the status of DR applications in detail. The capabilities of the proposed concept are evaluated in a real smart home in terms of various aspects

Evaluation of the effect of bun/albumin ratio on in-hospital mortality in hypertensive COVID-19 patients

OBJECTIVE: The impact of COVID-19 infection still continues all over the world and is an important cause of mortality. The mortality rate due to infection varies between 1-5%. The mortality rate is higher in those with cardiovascular risk factors, especially in cases with hypertension. Some studies have shown that blood urea nitrogen (BUN) and albumin levels are associated with worse prognosis in patients with COVID-19. In our study, we aimed to investigate whether the BUN/albumin (BAR) ratio has an effect on in-hospital mortality in hypertensive COVID-19 patients. PATIENTS AND METHODS: A total of 800 hypertensive COVID-19 patients, (618 of whom were alive and 182 died) were included in our study. Patients with a history of heart failure, malignancy, acute coronary syndrome, and myocarditis were excluded. RESULTS: The median age of the study population was 69 (60-77 IQR) years, and 305 (38%) of these patients were men. There was no statistically significant difference between the patients who died during follow-up and cases that remained alive in terms of comorbidities except chronic obstructive pulmonary disease (COPD) which was significantly lower in surviving group (p=0.014). Multivariable logistic regression analysis revealed that age [OR: 1.04, CI (1.01-1.06); p=0.002], male gender [OR: 1.85, CI (1.13-3.02); p=0.010], lymphocyte count [OR: 0.63, CI (0.40-0.98); p=0.038], SaO2 [OR: 0.82, CI (0.79-0.85); p<0.001] and BAR level [OR: 1.09, CI (1.04-1.16); p=0.001] were independent predictors of in-hospital mortality. ROC analysis yielded that BAR is a better predictor of in-hospital mortality compared to albumin and BUN alone. CONCLUSIONS: BUN, albumin, and BAR levels were found to be reliable predictors of in-hospital mortality in COVID-19 patients, and BAR was also found to be a more reliable predictor than BUN and albumin levels. Hypertension is one of the major risk factors for morbidity and mortality in COVID-19 and, BAR presents additional prognostic data in hypertensive COVID-19 patients that may direct physicians for treatment intensification

Prevalence of atopic disorders in rheumatic diseases

The aim of this study was to assess the point prevalences of hay fever, asthma, and atopic dermatitis in OA, RA, and AS, and to compare with healthy controls

Psychological status is associated with health related quality of life in patients with rheumatoid arthritis

Objective: Rheumatoid arthritis (RA) is a chronic and disabling disease frequently effects physical and psychological well being. The aim of the present study was to determine the impact of psychological status on health related quality of life in patients with RA and also to assess which quality of life (QoL) instrument - disease specific and generic - is more prone to this effect

The effect of idiopathic premature ventricular complexes on left ventricular ejection fraction.

Aim: Current literature lacks a definitive threshold of idiopathic premature ventricular complex (PVC) burden for predicting cardiomyopathy (CMP). The main objective of the present study was to evaluate relationship between the PVC burden and left ventricular ejection fraction (LVEF). Method: This multicenter, cross-sectional study included 341 consecutive patients with more than 1,000 idiopathic PVC in 24 hr of Holter monitoring admitted to the cardiology clinics between January 2019 and May 2019 in the nineteen different centers. The primary outcome was the LVEF measured during the echocardiographic examination. Result: Overall, the median age was 50 (38-60) and 139 (49.4%) were female. Percentage of median PVC burden was 9% (IQR: 4%-17.4%). Median LVEF was found 60% (55-65). We used proportional odds logistic regression method to examine the relationship between continuous LVEF and candidate predictors. Increase in PVC burden (%) (regression coefficient (RE) -0.644 and 95% CI -1.063, -0.225, p < .001), PVC QRS duration (RE-0.191 and 95% CI -0.529, 0.148, p = .049), and age (RE-0.249 and 95% CI -0.442, -0.056, p = .018) were associated with decrease in LVEF. This inverse relationship between the PVC burden and LVEF become more prominent when PVC burden was above 5%. A nomogram developed to estimate the individual risk for decrease in LVEF. Conclusion: Our study showed that increase in PVC burden %, age, and PVC QRS duration were independently associated with decrease in LVEF in patients with idiopathic PVC. Also, inverse relationship between PVC burden and LVEF was observed in lower PVC burden than previously known