A Brief Review of RIDH

The Reversible image data hiding (RIDH) is one of the novel approaches in the security field. In the highly sensitive domains like Medical, Military, Research labs, it is important to recover the cover image successfully, Hence, without applying the normal steganography, we can use RIDH to get the better result. Reversible data hiding has a advantage over image data hiding that it can give you double security surely

Design as a tool for reformation in the juvenile justice system through a participatory approach

Reformation and rehabilitation of children below 18 years of age who come in conflict with the law is overseen by the Juvenile Justice System in India. (4) The system reinforces “reformation” over deterrence but has been largely inaccessible and lesser known for long. (3) Through its Children’s Homes, the system aims at reformation but the varying attitudes and lack of sensitization while dealing with children has affected what reformation means. This paper starts with a look at the reformation in the juvenile justice system through a human centred lens throwing light on the pain-points of stakeholders at multiple stages and challenges to reformation. It further expands on research methodology led by design. These methods centred around gamifying research process helped greatly to interact with the children in the sensitive environment to build a conducive atmosphere where real insights could be shared. The ability to empathize with the stakeholders and using the design process to identify their needs, prototype and test new frameworks with them gave us an advantage as designers. Through dialogue, workshops and interactive sessions in the homes; the children presented perspectives which questioned the current view of reformation. The paper concludes with design interventions to make reformation a participatory process led by child as a contributing element of the society and a model critiquing and questioning aspects of the current system

Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer

MMP10, which is upregulated in 86% of primary tongue tumors with lymph node metastases, is negatively regulated by miR-944 and promotes nodal metastasis in an orthotopic tongue cancer mouse model through the AXL signaling pathway

Taurine deficiency as a driver of aging.

Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine decline with aging in mice, monkeys, and humans. A reversal of this decline through taurine supplementation increased the health span (the period of healthy living) and life span in mice and health span in monkeys. Mechanistically, taurine reduced cellular senescence, protected against telomerase deficiency, suppressed mitochondrial dysfunction, decreased DNA damage, and attenuated inflammaging. In humans, lower taurine concentrations correlated with several age-related diseases and taurine concentrations increased after acute endurance exercise. Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans

Taurine deficiency as a driver of aging

: Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine decline with aging in mice, monkeys, and humans. A reversal of this decline through taurine supplementation increased the health span (the period of healthy living) and life span in mice and health span in monkeys. Mechanistically, taurine reduced cellular senescence, protected against telomerase deficiency, suppressed mitochondrial dysfunction, decreased DNA damage, and attenuated inflammaging. In humans, lower taurine concentrations correlated with several age-related diseases and taurine concentrations increased after acute endurance exercise. Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans