Hombre de 31 años con dolor abdominal, diarrea y síndrome constitucional

A 31-year-old male with paroxysmal abdominal pain of 2 months of evolution and diarrhea. The complementary tests revealed the presence of multiple lymphadenopathy, splenomegaly, hypodense focal lesions in the liver and spleen, as well as an intra-ileum mass in the terminal ileum. Finally the diagnosis of Sarcoidosis with mainly digestive affectation is established. There are few cases described in the scientific literature of gastrointestinal Sarcoidosis. A high clinical suspicion is necessary for the diagnosis, and this is established within a clinical-radiological and anatomopathological context, excluding other causes of granulomatosis.Varón de 31 años con dolor abdominal paroxístico de 2 meses de evolución y cuadro diarreico. Las pruebas complementarias realizadas pusieron de manifiesto la presencia de múltiples adenopatías, esplenomegalia, lesiones focales hipodensas en hígado y bazo, así como una masa intraasa en íleon terminal. Finalmente se establece el diagnóstico de sarcoidosis con afectación principalmente digestiva. Existen pocos casos descritos en la literatura científica de sarcoidosis gastrointestinal. Para el diagnóstico es necesario una sospecha clínica alta, y este se establece dentro de un contexto clinicorradiológico y anatomopatológico, excluyendo otras causas de granulomatosis

Clinical Outcomes of Mechanical Thrombectomy in Stroke Tandem Lesions According to Intracranial Occlusion Location

This project was partially funded by the ISCIII project PI14/00971. The ITRIBiS project (Improving Translational Research Potential at the Institute of Biomedicine of Seville) has the registration number REGPOT-2013-1. Cooperative Cerebrovascular Disease Research Network (INVICTUS+) (RD16/0019/0015).Ye

Additional file 1 of Statistical analysis plan for the multicenter, open, randomized controlled clinical trial to assess the efficacy and safety of intravenous tirofiban vs aspirin in acute ischemic stroke due to tandem lesion, undergoing recanalization therapy by endovascular treatment (ATILA trial)

Additional file 1: Supplementary Material 1. Minor Revision. Supplementary Material 2. DSMB. Supplementary Material 3. Full protocol