A Global Perspective on Public Relations Professionalism: Mapping the Structure of Public Relations Associations’ International Networks

Associations play a powerful role in socializing practitioners. The presence of public relations associations across the world is one more step toward professionalization for the entire profession. This study examines the structure of global public relations professionalization manifested through the networks among international and national public relations professional associations. The findings of a cross-national, multilevel network analysis suggest that despite the overall dominance of international public relations associations, at the regional level, local centers have also emerged. In addition, European public relations associations have developed more relationships with other national, regional, and international associations than American-based professional associations.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Global civil society and a structural analysis of international NGOs's virtual networks

This dissertation sought to examine the virtual structure of global civil society via three theoretical frameworks: World System Theory, World Polity Theory and the current discussion of Network Society. Virtual interactions among 509 INGOs originating from 86 different countries and regions of the world were collected through data mining technology. Findings showed that, respectively, the three theories were significant at macro, meso and micro levels. Furthermore, this study showed that the collective consequence of technology use and the logics of network significantly affected the structure of the virtual networks of global civil society. Findings also revealed a trend of international inequality and Western dominance in the global civil arena. Theoretical and methodological implications were presented in the end

Optogenetic astrocyte activation modulates response selectivity of visual cortex neurons in vivo

Astrocytes play important roles in synaptic transmission and plasticity. Despite in vitro evidence, their causal contribution to cortical network activity and sensory information processing in vivo remains unresolved. Here we report that selective photostimulation of astrocytes with channelrhodopsin-2 in primary visual cortex enhances both excitatory and inhibitory synaptic transmission, through the activation of type 1a metabotropic glutamate receptors. Photostimulation of astrocytes in vivo increases the spontaneous firing of parvalbumin-positive (PV[superscript +]) inhibitory neurons, while excitatory and somatostatin-positive (SOM[superscript +]) neurons show either an increase or decrease in their activity. Moreover, PV[superscript +] neurons show increased baseline visual responses and reduced orientation selectivity to visual stimuli, whereas excitatory and SOM[superscript +] neurons show either increased or decreased baseline visual responses together with complementary changes in orientation selectivity. Therefore, astrocyte activation, through the dual control of excitatory and inhibitory drive, influences neuronal integrative features critical for sensory information processing.National Institutes of Health (U.S.)National Science Foundation (U.S.)Picower Institute for Learning and Memory (Innovation Fund)Simons FoundationMarie Curie International Outgoing Fellowship (FP7-253635)Consolider (CDS2010-00045)Ramon y Cajal Program (RYC-2012-12014

Preparation and Characterization of Mesoporous Zirconia Made by Using a Poly (methyl methacrylate) Template

Superfine powders of poly (methyl methacrylate) (PMMA) have been prepared by means of an emulsion polymerization method. These have been used as templates in the synthesis of tetragonal phase mesoporous zirconia by the sol–gel method, using zirconium oxychloride and oxalic acid as raw materials. The products have been characterized by infrared spectroscopy, X-ray diffraction analysis, transmission electron microscopy, N2adsorption-desorption isotherms, and pore size distribution. The results indicate that the average pore size was found to be 3.7 nm

Political Public Relations in Advocacy: Building Online Influence and Social Capital

This article explores how political public relations activities support advocacy efforts and allow organizations to communicate and partner with other organizations and individuals to affect change. Our study examined the organizational relationships that engaged in political advocacy to defeat the 2012 Stop Online Piracy Act (SOPA). We argue that networked social capital provides a theoretical framework for broadening the study of relationships from a dyadic approach to one that encompasses the multitude of relationships necessary to bring about change. Structural hole theory was used to identify influential organizations based on their network position. Two methods including a hyperlink network analysis of organizational websites involved in the Internet Blackout and a semantic network analysis of the SOPA legislation media coverage revealed three findings: 1) diverse ties enhance political advocacy, 2) political public relations can enhance network positions of organizations, and 3) evidence shows that social media can be used strategically to capitalize on political activism

Dopamine Neuron-Specific Optogenetic Stimulation in Rhesus Macaques.

Optogenetic studies in mice have revealed new relationships between well-defined neurons and brain functions. However, there are currently no means to achieve the same cell-type specificity in monkeys, which possess an expanded behavioral repertoire and closer anatomical homology to humans. Here, we present a resource for cell-type-specific channelrhodopsin expression in Rhesus monkeys and apply this technique to modulate dopamine activity and monkey choice behavior. These data show that two viral vectors label dopamine neurons with greater than 95% specificity. Infected neurons were activated by light pulses, indicating functional expression. The addition of optical stimulation to reward outcomes promoted the learning of reward-predicting stimuli at the neuronal and behavioral level. Together, these results demonstrate the feasibility of effective and selective stimulation of dopamine neurons in non-human primates and a resource that could be applied to other cell types in the monkey brain.This work was supported by the Wellcome Trust (Principal Research Fellowship and Programme Grant 095495), European Research Council (ERC Advanced Grant 293549), and NIH Caltech Conte Center (P50MH094258)

Case report: Novel NUS1 variant in a Chinese patient with tremors and intellectual disability

Introduction:Nuclear undecaprenyl pyrophosphate synthase 1 (NUS1) gene variants are associated with a range of phenotypes, including epilepsy, intellectual disability, cerebellar ataxia, Parkinson’s disease, dystonia, and congenital disorders of glycosylation. Additionally, cases describing genotypes and clinical features are rare.Case Presentation:Herein, we report the case of a 23-year-old Chinese female patient who presented with tremors, intellectual disability, and epilepsy. A history of carbon monoxide exposure, brain trauma, or encephalitis was not present in this case. Trio whole-exome sequencing analysis revealed a de novo pathogenic variant of c.750del in exon 4, leading to p.Leu251* amino acid substitution. Genetic analysis failed to identify the identical mutations in the remaining family members who underwent screening. The patient was diagnosed with a rare congenital disease, “congenital glycosylation disorder, type 1aa, autosomal dominant, type 55, with seizures (MRD-55).”Conclusion:We provide further evidence for the role of variants in NUS1 in the development of tremors, epilepsy, and intellectual disabilities. These findings expand our understanding of the clinical phenotypes of NUS1 variants