A Comparative study between Different Treatment Modalities of Floating Knee Jnjury At Aswan University Hospital

Purpose: The study aimed at presenting a comparison between the modalities of treatment different of floating knee injury at Aswan University Hospital.  Materials and Methods:  This study is a prospective study including all of our 20 cases of floating knee injuries who were treated utilizing various treatment modalities at Aswan University Hospital between December 2018 and September 2019 with a follow-up period of 12 months  Results: Based on the data analysis,  nailing is a better modality in floating knee injury (especially with diaphyseal long bone). Moreover, plating is a good choice for distal fractures, the external fixator is considered a choice for limb saving(as in popliteal ischemia, open fractures(OG3), and compartment syndrome).  Conclusion: Management of floating knee injury is critical as floating knee injury is not like other fractures. Floating knee injuries are serious injuries with a high rate of complications. Besides being caused by high-energy trauma with extensive skeletal and soft tissue damage, they are also associated with potentially life-threatening injuries of the head, chest, and abdomen. There are multiple controversies in surgical management starting from choosing suitable fixation for each patient according to variable conditions.  Floating knee injury remains a challenging orthopedic problem in which regaining good knee function outcome is a major concern. Stable osteosynthesis to achieve rigid fixation and early mobilization should always be attempted

SIWA WOMAN PARTICIPATION IN THE DEVELOPMENT OF ENVIRONMENTAL INDUSTRIES IN SIWA OASIS

ABSTRACT   The research aimed to determine the level of participation of  Siwa Woman in the development of environmental industries, And determine the relationship between the independent variables and the degree of the level of participation of  Siwa Woman in the development of environmental industries, Determine the percentage contribution of variables moral relationship level of Siwa woman participation in the development of environmental industries, and to identify the motives of Siwa Woman in the development of environmental industries. This research was conducted in Siwa Oasis, It was selected sample of (256) respondents by 33.6% of the overall size, data were collected by using a questionnaire specially to achieve the research objectives, the statistical tools included percentage  Frequencies,  Pearson's correlation coefficient were used to data analysis.   The study concluded the following key results   The results showed that respondents with low participation in handmade carpets industry is 14.7%, While the respondents with medium participation is 22.3%, while respondents with high participation is 63%. The results indicate that the percentage ofrespondents with low participation in pickling olives are 12.3%, While the percentage of respondents medium participation is 15.9%, while the proportion of respondents with a high participation is 71.8 percent. The results showed that respondents with low participation in the manufacture of animal feed ratio is 17.2%, While the percentage of respondents medium participation is 15.2%, while the proportion of respondents with a high participation is 63.6 percent. Data suggests that respondents with low participation in the garment manufacturing Siwa is 7.3%, While the percentage of respondents participating medium is 9.9%, while the proportion of respondents with a high participation in the garment manufacturing Siwa is 82.8%. Results show that in the category of 7.8% total participation level low in the development of environmental industries, and 16.4% of them fall in the proportion of middle-class participation for the development of environmental industries, And 75.8% of the respondents fall in the category of high participation for the development of environmental industries in Siwa Oasis. Results show that the level of Siwa woman participation in the development of environmental industries was a significant relation at a level of 0.01 in all of: Capacity animal tenure, The degree of belonging to the tribal community, and the degree of adherence to tribal customs and traditions, Degree trend towards environmental industries, and the degree of exposure to sources of information on the environmental industries, As the value of simple correlation coefficient of Pearson: 0.225, 0.241, 0.217, 0.219, and 0.231, respectively, While the relationship was significant at the 0.05 level with age, While respondents 0.149 Pearson simple correlation coefficient values, and there was no significant relation to: the degree of education of the surveyed, the area of agricultural holdings. It turns out that the percentage contribution of these variables in explaining the contrast kidney respondents were significant at the 0.01 level And its contribution was all in the predictive ability and the other is 51.5%, of which 35.2% to the degree of exposure to sources of information on environmental industries, 9.5% to the point of belonging to the tribal community, and 5% to the degree of adherence to tribal customs and traditions, to 1.8% and the degree of the trend toward environmental industries. The results showed that the most important motives of Siwa woman in the development of environmental industries are: Increasing the family income to their participation in the environmental industries (89.5%), Help the family in the bride processing (83.9%), Out of the house to receive an education and to work in the environmental industries (76.7%)

Adipose Tissue-Derived Mesenchymal Stem Cell Modulates the Immune Response of Allergic Rhinitis in a Rat Model

This study was designed to investigate the potential effects and underlying mechanism of adipose tissue-derived mesenchymal stem cells (MSCs) on allergic inflammation compared to Montelukast as an antileukotriene drug in a rat model of allergic rhinitis (AR). The effect of MSCs was evaluated in albino rats that were randomly divided into four (control, AR, AR + Montelukast, and AR + MSCs) groups. Rats of AR group were sensitized by ovalbumin (OVA) and then challenged with daily nasal drops of OVA diluted in sterile physiological saline (50 μL/nostril, 100 mg/mL, 10% OVA) from day 15 to day 21 of treatment with/without Montelukast (1 h before each challenge) or MSCs I/P injection (1 × 106 MCSs; weekly for three constitutive weeks). Both Montelukast and MSCs treatment started from day 15 of the experiment. At the end of the 5th week, blood samples were collected from all rats for immunological assays, histological, and molecular biology examinations. Both oral Montelukast and intraperitoneal injection of MSCs significantly reduced allergic symptoms and OVA-specific immunoglobulin E (IgE), IgG1, IgG2a and histamine as well as increasing prostaglandin E2 (PGE2). Further analysis revealed that induction of nasal innate cytokines, such as interleukin (IL)-4 and TNF-α; and chemokines, such as CCL11 and vascular cell adhesion molecule-1 (VCAM-1), were suppressed; and transforming growth factor-β (TGF-β) was up-regulated in Montelukast and MSCs-treated groups with superior effect to MSCs, which explained their underlying mechanism. In addition, the adipose tissue-derived MSCs-treated group had more restoring effects on nasal mucosa structure demonstrated by electron microscopical examination