29,229 research outputs found
Clinical and molecular characterization of both methicillin-resistant andsensitive staphylococcus aureus mastitis
NO ABSTRACT AVAILABLEThis study targeted bovine mastitis as a possible source of livestock-associated methicillin-resistant Staphylococcus aureus (MRSA), to identify clinical signs associated with MRSA- and non-MRSA-associated mastitis. Thirty-eight mastitis cases (68 infected quarters) were investigated. Gram-positive cocci-shaped isolates were selected based on Baird Parker agar growth as well as Gram-stained bacterial smears. Molecular screening for Staphylococcus aureus (S. aureus) yielded 17 isolates, of which five (29.41%) were methicillin resistant. The five isolates were mecA positive, but mecC negative. Multilocus sequence typing (MLST) indicated that sequence type 1 (ST1) was the identified type of all isolates of MRSA. S. aureus-associated cases showed different clinical forms of mastitis, including subclinical, acute, chronic, and gangrenous. Additionally, subclinical mastitis was the only detected condition associated with MRSA, which may represent a potential hidden risk for humans. Phenotypically, isolates of MRSA showed resistance to all of the tested β-lactam antimicrobials, with marked resistance to tetracycline and gentamycin. Based on our knowledge, this is the first report to identify MRSA ST1 in Egypt. Bovine mastitis could be a source for the dissemination of MRSA to humans and other animals. Additionally, while methicillin-resistance may have no effect on the clinical outcome of mastitis, it does affect therapeutic success, particularly when β-lactam antimicrobials are used
Coulomb blockade in silicon based structures at temperatures up to 50 K
Coulomb blockade has been observed in the current-voltage characteristics of structures fabricated in silicon germanium delta-doped material at temperatures up to 50 K. This is consistent with the estimated effective tunnel capacitance of 10 aF which is significantly smaller than the reported capacitances of tunnel junctions made from Al or GaAs/AlGaAs heterostructures
Hard diffraction in hadron--hadron interactions and in photoproduction
Hard single diffractive processes are studied within the framework of the
triple--Pomeron approximation. Using a Pomeron structure function motivated by
Regge--theory we obtain parton distribution functions which do not obey
momentum sum rule. Based on Regge-- factorization cross sections for hard
diffraction are calculated. Furthermore, the model is applied to hard
diffractive particle production in photoproduction and in
interactions.Comment: 13 pages, Latex, 13 uuencoded figure
Delta-Function Potential with a Complex Coupling
We explore the Hamiltonian operator H=-d^2/dx^2 + z \delta(x) where x is
real, \delta(x) is the Dirac delta function, and z is an arbitrary complex
coupling constant. For a purely imaginary z, H has a (real) spectral
singularity at E=-z^2/4. For \Re(z)<0, H has an eigenvalue at E=-z^2/4. For the
case that \Re(z)>0, H has a real, positive, continuous spectrum that is free
from spectral singularities. For this latter case, we construct an associated
biorthonormal system and use it to perform a perturbative calculation of a
positive-definite inner product that renders H self-adjoint. This allows us to
address the intriguing question of the nonlocal aspects of the equivalent
Hermitian Hamiltonian for the system. In particular, we compute the energy
expectation values for various Gaussian wave packets to show that the
non-Hermiticity effect diminishes rapidly outside an effective interaction
region.Comment: Published version, 14 pages, 2 figure
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